Synthesis of a novel conformational restricted amino acid for potential use in peptide chemistry

2009 ◽  
Vol 15 (6) ◽  
Author(s):  
Wei-wei WANG ◽  
Ting YU ◽  
Chao WANG
Keyword(s):  
Amino Acid ◽  
Peptide Chemistry ◽  
Potential Use

scholarly journals Morphology and molecular characterization of newly isolated microalgae strain Chlorella volutis LIPI13-WKT066 from Wakatobi Islands and its potential use

2019 ◽  
Vol 23 (1) ◽  
pp. 13
Author(s):  
Delicia Yunita Rahman ◽  
Swastika Praharyawan ◽  
Sapto Raharjo ◽  
Farizul Fadiyah ◽  
Dwi Susilaningsih
Keyword(s):  
Amino Acid ◽  
Molecular Characterization ◽  
Acid Content ◽  
National Park ◽  
Amino Acid Content ◽  
Morphological Observation ◽  
Future Application ◽  
Health Application ◽  
Potential Use

Morphology and molecular characterization of microalgae isolated from Wakatobi Marine National Park was conducted. An understanding of the characteristics of morphology, molecular, as well as metabolites profile of the microalgae species is potentially useful for its future application. The primary aim of this study was to isolate, identify and characterize the microalgae strain isolated from Wakatobi Marine National Park labeled as LIPI13-WKT066 with the emphasis on the evaluation of amino acid content as a basis for its health application. Morphological observation under the microscope and molecular identification suggested that the microalgae strain of LIPI13-WKT066 belong to the strain under species of Chlorella volutis. Metabolite characterization of the microalgae strain showed that the content of protein (11.9%), lipid (12.4%) and carbohydrate (4.7%) was in the regular range. Further analysis of its amino acid content revealed the potency of the microalgae strain to be used as antihypertensive agent.

Nutritional Aspects of CAPD and the Potential Use of Amino Acid Containing Dialysis Solutions

1983 ◽  
Vol 3 (1_suppl) ◽  
pp. 10-12 ◽  
Author(s):  
Oimitrios G. Oreopoulos ◽  
Errol Marliss G. Harvey ◽  
Anderson Arie Oren ◽  
Nicholas Oombros Paul ◽  
Williams Ramesh Khanna ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Plasma Amino Acid ◽  
Plasma Amino Acids ◽  
Effective Solution ◽  
Nutrient Losses ◽  
Protein Meal ◽  
Dialysis Solution ◽  
Dialysis Solutions ◽  
Potential Use

As a result of a combination of a decreased appetite with increased nutrient losses in the dialysate, a number of CAPO patients may develop malnutrition. A decrease in appetite is also observed in normal animals undergoing CAPO which suggests that some factors related to CAPO influence appetite so that these animals eat less. In addition to protein losses, CAPO patients are losing approximately two grams of amino acids a day, and they have plasma amino acid abnormalities similar to those produced by malnutrition and uremia. An amino acid-containing dialysis solution (2%) is an effective solution with respect to ultrafiltration and solute removal. Amino acids can be absorbed by the peritoneal route and produce an increase in plasma amino acids to levels similar to those observed after a protein meal. These observations indicate that administration of amino acids via the peritoneal route may prevent or correct malnutrition developed in patients on CAPO.

scholarly journals The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy

2014 ◽  
Vol 9 (6) ◽  
pp. 293-303 ◽  
Author(s):  
Yangzom D. Bhutia ◽  
Ellappan Babu ◽  
Puttur D. Prasad ◽  
Vadivel Ganapathy
Keyword(s):  
Amino Acid ◽  
Amino Acid Transporter ◽  
Acid Transporter ◽  
Potential Use

Synthesis of 1,2-Dithiolane Analogues of Leucine for Potential Use in Peptide Chemistry

2002 ◽  
Vol 4 (7) ◽  
pp. 1139-1142 ◽  
Author(s):  
Enrico Morera ◽  
Francesco Pinnen ◽  
Gino Lucente
Keyword(s):  
Peptide Chemistry ◽  
Potential Use

scholarly journals Iron-Binding and Anti-Fenton Properties of Novel Amino Acid-Derived Cyclic Imide Dioximes

Antioxidants ◽  
2019 ◽  
Vol 8 (10) ◽  
pp. 473 ◽  
Author(s):  
Janez Mravljak ◽  
Žiga Jakopin
Keyword(s):  
Molecular Structure ◽  
Amino Acid ◽  
Antioxidant Properties ◽  
Binding Motif ◽  
Iron Binding ◽  
Iron Cycling ◽  
Cyclic Imide ◽  
Structural Requirements ◽  
Chelating Ability ◽  
Potential Use

We present a novel route for the preparation of amino acid-derived cyclic imide dioxime derivatives. Readily accessible amino acids were conveniently converted to their corresponding cyclic imide dioximes in simple synthetic steps. The aim of this work was to describe and compare the iron-chelating and antioxidant properties of synthesized compounds in relation to their molecular structure, and in particular, which of those features are essential for iron(II)-chelating ability. The glutarimide dioxime moiety has been established as an iron(II)-binding motif and imparts potent anti-Fenton properties to the compounds. Compound 3 was shown to strongly suppress hydroxyl radical formation by preventing iron cycling via Fe-complexation. These findings provide insights into the structural requirements for achieving anti-Fenton activity and highlight the potential use of glutarimide dioximes as antioxidants.

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