Are hypertensive patients with history of coronary artery disease at risk for silent lower extremity artery disease?

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Eka Prasetya Budi Mulia ◽  
Kevin Yuwono ◽  
Raden Mohammad Budiarto
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Lower Extremity ◽  
Pearson Correlation ◽  
Ankle Brachial Index ◽  
Chi Square ◽  
Hypertensive Patients ◽  
History Of ◽  
Artery Disease ◽  
Lower Extremity Artery Disease

Abstract Objectives We aimed to investigate the association between hypertension and asymptomatic lower extremity artery disease (LEAD) in outpatients with known history of coronary artery disease (CAD). Methods Patients with known history of CAD who have been undergone coronary angiography and have significant coronary artery stenosis (more than 60%) were included. LEAD was defined as ankle-brachial index (ABI) < 0.9 in either leg. The risk of LEAD in hypertensive group was analyzed using chi-square test, and correlation between blood pressure (BP) and ABI was analyzed using Pearson correlation test in SPSS v.25. Results One hundred and four patients were included. 82.7% of patients were male. Mean age was 57.05 ± 7.97. The prevalence of hypertension was 35.6%, and the prevalence of LEAD was 16.3%. A higher proportion of LEAD was found in hypertensive (18.9%) compared to non-hypertensive (14.9%), although not statistically significant (OR: 1.33; 95% CI: 0.46 to 3.85; p=0.598). There was an association between ABI and systolic BP (p=0.016), but not with diastolic BP (p=0.102). Conclusions Our study showed that the prevalence of LEAD in hypertension, especially in the CAD population, is relatively high. There was no association between hypertension and LEAD, but a higher prevalence of LEAD was found in hypertensive patients. Nevertheless, LEAD screening is still recommended in hypertensive patients, especially in the CAD population, given the fact that outcomes of health and mortality are worse for those with concomitants of these diseases.

scholarly journals Ankle-brachial Index and associated factors in individuals with coronary artery disease

2020 ◽  
Vol 66 (4) ◽  
pp. 407-413
Author(s):  
Saulo Henrique Salgueiro de Aquino ◽  
Isabelle Tenório Melo ◽  
Carlos Dornels Freire de Souza ◽  
Francisco de Assis Costa
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Family History ◽  
Ankle Brachial Index ◽  
Chi Square ◽  
Significant Difference ◽  
History Of ◽  
Artery Disease

SUMMARY OBJECTIVE Analyzing the association between ABI and the main risk factors for coronary artery disease in coronary patients. METHODS Were selected 156 adult patients from a hospital in Maceió, Alagoas. Were evaluated with risk factors age, obesity, hypertension, diabetes mellitus, smoking, and dyslipidemia. PAOD screening was performed by the ankle-brachial index (ABI). The Mann-Whitney, chi-square, and Fisher’s exact tests were used. Confidence Interval of 95% and a significance of 5%. RESULTS 67.3% (n=105) males, 52.6% (n=82) elderly, 23.1% (n = 34) obese, 72.4% 6% (n=113) hypertensive, 34.6% (n=54) diabetics, 53.2% (n=83) smokers, 34.6% (n=54) dyslipidemic and 70.5% (n=110) with a family history of CAD. 16.7% (n=26) of the individuals presented PAOD. Three factors were associated with PAOD: age group ≥ 60 years (OR:3.656; p=0.005), diabetes mellitus (OR:2.625; p=0.024) and hypertension (OR:5.528; p=0.008). No significant difference was observed in the variables smoking, dyslipidemia, family history of CAD, and obesity. CONCLUSION The independent risk factors for PAOD were age, diabetes mellitus, and systemic arterial hypertension.

scholarly journals RETRACTED ARTICLE: Association of severity of coronary artery disease by SYNTAX score (SS) and lower extremity arterial disease by duplex ultrasound (DUS) study—an Indian perspective

2020 ◽  
Vol 72 (1) ◽  
Author(s):  
Saumen Nandi ◽  
Anindya Mukherjee ◽  
Dibbendhu Khanra ◽  
Kaushik Biswas
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Lower Extremity ◽  
Indian Subcontinent ◽  
Ankle Brachial Index ◽  
Duplex Ultrasound ◽  
Arterial Disease ◽  
Smoking History ◽  
Syntax Score ◽  
Artery Disease

Abstract Background Coronary artery disease (CAD) and lower extremity artery disease (LEAD) often coexist. Ankle brachial index (ABI) has been shown to be an independent predictor of CAD. Studies have reported correlation of CAD and LEAD on the basis of ABI and also invasive angiography. But rigorous searching did not reveal any similar research where severity of LEAD was assessed by duplex ultrasound (DUS). In this study, we assessed the association of severity and localisation of LEAD by DUS with SYNTAX score (SS). Results A total of 637 subjects above 45 years of age with coronary angiographic confirmation of CAD were studied in this single centre cross-sectional, descriptive and analytical research. High SS was significantly more common in subjects with LEAD (p = 0.04). In the femoro-popliteal segment, total occlusion of arteries was found in significantly more proportion of subjects with high SS. A progressive increase in mean SS was noted across the grades of arterial disease in the femoro-popliteal segment (p = 0.007). 85.2% of the LEAD was in the femoro-popliteal segment, while below-knee arterial disease was present in 98.5% of subjects with LEAD. Hypertension, smoking, history of CVE and presentation with ACS independently increased the risk of LEAD. Conclusion High prevalence of asymptomatic LEAD and association of high SS with LEAD as a whole as well as femoro-popliteal involvement suggests the need for a point of care DUS study (POCUS) since treatment varies with location and extent of disease which cannot be fathomed by ABI alone. Being the largest study on association of CAD and LEAD from Indian subcontinent till date and also the first study to use non-invasive tool as DUS for LEAD assessment while studying its association with CAD makes this a landmark experience.

scholarly journals Lower Extremity Artery Disease as a Predictor of Coronary Artery Disease

2021 ◽  
Vol 26 (1) ◽  
pp. 21-24
Author(s):  
Cornel Ioan Bitea ◽  
Ioan Maniţiu ◽  
Georgiana Bălțat
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Lower Extremity ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Arterial Lumen ◽  
Arterial Lesions ◽  
Artery Disease ◽  
Lower Extremity Artery Disease

Abstract Coronary artery disease (CAD) is an important determinant of long-term outcome in patients with lower extremity artery disease (LEAD). In this study we evaluated the CAD prevalence among LEAD patients and the association of LEAD lesions location with the CAD presence and severity. 203 patients with LEAD, referred for peripheral and simultaneous coronary angiography, were evaluated. LEAD and CAD were considered angiographically significant for stenosis higher than 50% of arterial lumen. More than two-thirds of LEAD patients had significant CAD, half of them having multi-vessel CAD and a quarter single CAD. Infrapoplitheal arterial lesions seemed to be the strongest predictor of CAD being associated with significant and multi-vessel CAD and also with the presence of left main (LM) lesions. Femoral artery lesions were highly associated with multi-vessel CAD, but there was no association with significant CAD and LM lesions. No association was found between iliac artery lesions and CAD.

scholarly journals The relapse of coronary artery disease in patients with diabetes mellitus at Dr. Ramelan Navy Hospital, Surabaya, Indonesia

2019 ◽  
Author(s):  
Priyo Mukti Pribadi Winoto ◽  
Ahsan Ahsan ◽  
Tina Handayani Nasution
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Sampling Technique ◽  
P Value ◽  
Chi Square ◽  
History Of ◽  
Artery Disease ◽  
Chi Square Analysis

The patients with coronary artery disease are susceptible to experience the relapse so that the control towards the risk factors of coronary artery disease is needed such as a history of hypertension, dyslipidemia, suffering from diabetes mellitus, medication adherence, and history of obesity. This study aimed at knowing the relationship between the risk factor of diabetes mellitus and the relapse of coronary artery disease. This study was an analytical observation by using retrospective cohort. The total respondent was 189 people taken by using purposive sampling technique. The finding showed that nearly all patients (82.5%) did not suffer from diabetes mellitus, and most of them (72.5%) experienced the relapse of CAD. The result of the chi-square analysis showed that the p-value of 0.009 < α = 0.05, indicating a significant relationship between Diabetes Mellitus and the relapse of coronary artery disease. The patient with diabetes mellitus has a higher risk of experiencing the relapse of CAD. The nurse should concern and control the risk factors of coronary artery disease that affects the relapse.

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