In-vitro anthelmintic activity of three Bangladeshi plants against Paramphistomum cervi and Haemonchus contortus

2015 ◽  
Vol 12 (2) ◽  
Author(s):  
Md. Khirul Islam ◽  
Md. Afjalus Siraj ◽  
Asit Baron Sarker ◽  
Sanjib Saha ◽  
Imran Mahmud ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Haemonchus Contortus ◽  
Leaf Extract ◽  
Anthelmintic Activity ◽  
Therapeutic Tool ◽  
Lead Compounds ◽  
Continuous Evaluation ◽  
The World ◽  
Paramphistomum Cervi

Abstract: Conventional plant-based therapies act as an important therapeutic tool for the treatment of worm infections all over the world and continuous evaluation of medicinal plants to find new potential lead compounds should be carried out.:: Among all three concentrations (25, 50, and 100 mg/mL), the hydroalcoholic leaf extract of:

In vitro anthelmintic activity of crude extracts of selected medicinal plants against Haemonchus contortus from sheep

2012 ◽  
Vol 87 (2) ◽  
pp. 174-179 ◽  
Author(s):  
M. Ahmed ◽  
M.D. Laing ◽  
I.V. Nsahlai
Keyword(s):  
Medicinal Plants ◽  
Haemonchus Contortus ◽  
Allium Sativum ◽  
Anthelmintic Activity ◽  
Ananas Comosus ◽  
Lespedeza Cuneata ◽  
Aloe Ferox ◽  
Ethanol Extracts

AbstractEthanol extracts of 25 plant species were screened for anthelmintic effects against Haemonchus contortus. Ethanol extracts of each plant were used at various concentrations (10, 20 and 30%) to treat 10-day faecal cultures, incubated at 27°C with control cultures which were treated with ethanol for 48 h. Five plants with high efficacies (Ananas comosus, Aloe ferox, Allium sativum, Lespedeza cuneata and Warburgia salutaris) were selected from the first screening for further investigation using ethanol, dichloromethane and water extracts at four concentrations (2.5, 5, 10 and 20%). Ethanol was the most effective solvent. Larval counts decreased with increasing extract concentrations, of which 10 and 20% had similar effects. Lespedeza cuneata caused more than 70% mortality at all concentrations. However, there remains a need to assess in vivo efficacy of these plants.

scholarly journals In vitro anthelmintic activity of aqueous leaf extract of Annona muricata L. (Annonaceae) against Haemonchus contortus from sheep

2013 ◽  
Vol 134 (3) ◽  
pp. 327-332 ◽  
Author(s):  
L.E. Ferreira ◽  
P.M.N. Castro ◽  
A.C.S. Chagas ◽  
S.C. França ◽  
R.O. Beleboni
Keyword(s):  
Haemonchus Contortus ◽  
Leaf Extract ◽  
Anthelmintic Activity ◽  
Annona Muricata ◽  
Aqueous Leaf Extract

Natural products from the traditional Moroccan pharmacopoeia: A potential lead for the prevention and treatment of COVID-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1278-1285
Author(s):  
Mohamed Yafout ◽  
Amine Ousaid ◽  
Ibrahim Sbai El Otmani ◽  
Youssef Khayati ◽  
Amal Ait Haj Said
Keyword(s):  
Medicinal Plants ◽  
Plant Extracts ◽  
Molecular Mechanisms ◽  
Scientific Literature ◽  
Treatment Protocol ◽  
World Health ◽  
The World ◽  
Health Organization ◽  
Promising Source

The new SARS-CoV-2 belonging to the coronaviruses family has caused a pandemic affecting millions of people around the world. This pandemic has been declared by the World Health Organization as an international public health emergency. Although several clinical trials involving a large number of drugs are currently underway, no treatment protocol for COVID-19 has been officially approved so far. Here we demonstrate through a search in the scientific literature that the traditional Moroccan pharmacopoeia, which includes more than 500 medicinal plants, is a fascinating and promising source for the research of natural molecules active against SARS-CoV-2. Multiple in-silico and in-vitro studies showed that some of the medicinal plants used by Moroccans for centuries possess inhibitory activity against SARS-CoV or SARS-CoV-2. These inhibitory activities are achieved through the different molecular mechanisms of virus penetration and replication, or indirectly through stimulation of immunity. Thus, the potential of plants, plant extracts and molecules derived from plants that are traditionally used in Morocco and have activity against SARS-CoV-2, could be explored in the search for a preventive or curative treatment against COVID-19. Furthermore, safe plants or plant extracts that are proven to stimulate immunity could be officially recommended by governments as nutritional supplements.

Chemical characterization and in vitro anthelmintic activity of Citrus bergamia Risso and Citrus X paradisii Macfad essential oil against Haemonchus contortus Kirby isolate

Acta Tropica ◽  
2021 ◽  
Vol 217 ◽  
pp. 105869
Author(s):  
Vivien Patricia Garbin ◽  
Beatriz Munguía ◽  
Jenny Carolina Saldaña ◽  
Cícero Deschamps ◽  
Roger Raupp Cipriano ◽  
...  
Keyword(s):  
Essential Oil ◽  
Haemonchus Contortus ◽  
Chemical Characterization ◽  
Anthelmintic Activity ◽  
Citrus Bergamia

In vitro anthelmintic activity of Dennettia tripetala G. Baker (Annonaceae) Fruits against Haemonchus contortus

2021 ◽  
Author(s):  
Rachel A. Nwosu ◽  
Mohammed M. Suleiman ◽  
Hussaina J. Makun ◽  
Matthew P. Ameh ◽  
Manji A. Shetshak ◽  
...  
Keyword(s):  
Haemonchus Contortus ◽  
Anthelmintic Activity ◽  
Dennettia Tripetala

In Vitro Nematocidal Effect and Anthelmintic Activity of Artemisia cina Against Haemonchus contortus in Gerbils and Relative Expression of Hc29 Gene in Transitional Larvae (L3–L4)

2021 ◽  
Author(s):  
Rosa Isabel Higuera-Piedrahita ◽  
Mariana Dolores-Hernández ◽  
Luis Gerardo Jiménez-Pérez ◽  
Brígida C. Camacho-Enríquez ◽  
Alejandro Zamilpa ◽  
...  
Keyword(s):  
Haemonchus Contortus ◽  
Anthelmintic Activity ◽  
Relative Expression

Anthelmintic activity in vitro of Citrus sinensis and Melaleuca quinquenervia essential oil from Cuba on Haemonchus contortus

2015 ◽  
Vol 76 ◽  
pp. 647-652 ◽  
Author(s):  
Yousmel Aleman Gaínza ◽  
Luciana Ferreira Domingues ◽  
Oriela Pino Perez ◽  
Márcio Dias Rabelo ◽  
Eugenio Roque López ◽  
...  
Keyword(s):  
Essential Oil ◽  
Haemonchus Contortus ◽  
Citrus Sinensis ◽  
Anthelmintic Activity ◽  
Melaleuca Quinquenervia

scholarly journals The effects of flubendazole and its metabolites on the larval development of Haemonchus contortus (Nematoda: Trichostrongylidae): an in vitro study

2010 ◽  
Vol 47 (4) ◽  
pp. 269-272 ◽  
Author(s):  
H. Bártíková ◽  
L. Skálová ◽  
J. Lamka ◽  
B. Szotáková ◽  
M. Várady
Keyword(s):  
Larval Development ◽  
Haemonchus Contortus ◽  
Anthelmintic Activity ◽  
In Vitro Study ◽  
Lethal Concentration ◽  
Resistant Isolate ◽  
Susceptible Isolate ◽  
Marked Resistance ◽  
Larval Development Test

AbstractThe anthelmintic effects of flubendazole (FLU), its two main metabolites reduced flubendazole (FLU-R) and hydrolyzed flubendazole (FLU-H), and thiabendazole (TBZ) were compared using an in vitro larval development test in two isolates of Haemonchus contortus, a fully susceptible isolate (HCS) and a multi-resistant isolate (HCR). Results were quantified as 50 % lethal concentration (LC50), 99 % lethal concentration (LC99), efficacy factor (EF), and resistance factor (RF). For HCS, both LC50 and LC99 of FLU were lower than those of the reference TBZ. The anthelmintic activity of FLU-R in HCS and HCR was 13 and 6 times lower than the activity of FLU, respectively. The anthelmintic activity of FLU-H was negligible (approximately 363–853 times lower) compared to that of FLU. Although a marked resistance of the HCR isolate to TBZ was confirmed, only a low tolerance to FLU-R and slightly higher tolerance to FLU were found.

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