Assessment of fetal Doppler parameters in pregnant women with COVID-19 infection: a prospective case-control study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Sule Goncu Ayhan ◽  
Atakan Tanacan ◽  
Aysegul Atalay ◽  
Selcan Sinaci ◽  
Eda Ozden Tokalioglu ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Ductus Venosus ◽  
Control Group ◽  
City Hospital ◽  
Fetal Doppler ◽  
Control Study ◽  
Prospective Case Control Study ◽  
Demographic Features

Abstract Objectives To investigate the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on fetal Doppler parameters. Methods This was a prospective case-control study conducted in Ankara City Hospital with confirmed SARS-CoV-2 infected pregnants between August 1, 2020 and October 1, 2020. There were 54 COVID-19 confirmed pregnant women and 97 age-matched pregnant women as a control group between 28 and 39 weeks. Infection was confirmed based on positive real-time polymerase-chain reaction results. Demographic features, uterine artery (right, left), umblical artery, middle cerebral artery, ductus venosus, cerebro-placental ratio, and cerebral-placental-uterine ratio Doppler parameters were investigated in both groups. Results Two groups were similar in terms of demographic features and no difference was found for fetal Doppler parameters. Conclusions COVID-19 seems to have no adverse effect on fetoplacental circulation in mild and moderate patients during the acute phase of the infection.

scholarly journals The impact of COVID-19 infection on the cytokine profile of pregnant women: A prospective case-control study

Cytokine ◽  
2021 ◽  
Vol 140 ◽  
pp. 155431
Author(s):  
Atakan Tanacan ◽  
Nuray Yazihan ◽  
Seyit Ahmet Erol ◽  
Ali Taner Anuk ◽  
Fatma Didem Yucel Yetiskin ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Cytokine Profile ◽  
The Impact ◽  
Control Study ◽  
Prospective Case Control Study

Pregnancy outcomes in adolescents: a case-control study in the West of Iran

2021 ◽  
Vol 17 ◽  
Author(s):  
Salman Khazaei ◽  
Saeid Bashirian ◽  
Akram Bathaei ◽  
Mohadese Sadri ◽  
Fateme Shirani ◽  
...  
Keyword(s):  
Prenatal Care ◽  
Pregnant Women ◽  
Adolescent Pregnancy ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Adult Women ◽  
The West ◽  
Adolescent Women ◽  
Control Study

Background: Adolescent pregnancy, pregnancy in women aged between 13-19 years, is considered a major health problem. Objective: This study was performed to determine the maternal, perinatal, and neonatal outcomes of adolescent pregnancies. Materials and Methods: The present hospital-based case-control study was performed on pregnant women who were referred to Fatemieh Hospital in Hamadan City for delivery. The case group was pregnant women whose gestational age was less than 19 years (adolescent pregnancy) and the control group included pregnant women whose gestational age was at 19-35 years (adult women pregnancy). Data were analyzed using Stata software version 14. The significant level was considered less than 0.05. Results: The unwanted pregnancy was significantly higher in adolescent women (45% vs. 28.5%, P=0.002). 18% of adolescent women had the experience of spouse violence compared to 4.25% in the control group (P<0.001). Accessing prenatal care and supplements were significantly higher in adult women (P<0.05). The adult mothers had significantly higher cesarean section delivery compared adolescent group (54.91% vs. 33%, P<0.001). Also, there was a significant association between postpartum hemorrhages and the study group (22% in cases compared to 13.75% in the control group, P=0.04). The Apgar score 1 minute was significantly higher in adult mothers (8.05±2.08 vs. 7.39±2.05, P<0.001). Conclusion: In conclusion, adolescent mothers in the west of Iran had a higher risk of inadequate prenatal care, low Apgar score and postpartum hemorrhage. Therefore, society should focus on public health policies that can improve the adequacy of prenatal care among adolescents.

scholarly journals Mode of Delivery in Drug-Dependent Pregnant Women: A Case Control Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ana Raquel Neves ◽  
Fabiane Neves ◽  
Isabel Santos Silva ◽  
Maria do Céu Almeida ◽  
Pitorra Monteiro
Keyword(s):  
Pregnant Women ◽  
Vaginal Delivery ◽  
Case Control Study ◽  
Mode Of Delivery ◽  
Case Control ◽  
Control Group ◽  
Maternal Characteristics ◽  
Drug Dependent ◽  
Route Of Delivery ◽  
Control Study

Objective. To determine the contribution of drug use during pregnancy to the route of delivery.Methods. A case-control study was conducted at a hospital in Coimbra, Portugal, between 2001 and 2014. Drug-dependent pregnant women (n=236) were compared with a control group of low risk women (n=228) in terms of maternal characteristics, obstetric history, pregnancy complications, and labor details. Factors that influenced the mode of delivery were determined. Statistical analysis was performed with SPSS v. 23.0 (IBM Corp.).pvalues < 0.05 were considered statistically significant.Results. Drug-dependent women presented a lower rate of cesarean delivery (18.2 versus 28.9%,p=0.006). After adjusting for the factors that were significantly related to the mode of delivery, drug dependency influenced the rate of cesarean section (β=0.567; 95% CI = 0.328–0.980). Within the drug-dependent group, the mode of delivery was significantly related to previous cesarean or vaginal delivery (p=0.008andp<0.001, resp.) and fetal presentation (p<0.001), but not with the type of drug, route of administration, or substitution maintenance therapy.Conclusions. The drug-dependent group presented a significantly higher rate of vaginal delivery. However, this was not associated with the behavioral factors analyzed. We hypothesize that other social and psychological factors might explain this difference.

scholarly journals Cytomegalovirus Viremia and Risk Factors in Renal Transplant Recipients in Iran: a Prospective Case-control Study

2021 ◽  
Author(s):  
Najmeh Parhizgari ◽  
Farhad Rezaei ◽  
Mohamad-Reza Khatami ◽  
Sayed Mahdi Marashi ◽  
Mohammad Farahmand ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Kidney Transplant ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Transplant Recipients ◽  
Transplant Patients ◽  
Kidney Transplant Patients ◽  
Control Study ◽  
Prospective Case Control Study

Abstract Background: In spite of effective anti-viral drugs and risk-balanced prophylaxis regimen, cytomegalovirus (CMV) remains a major reason of morbidity in kidney transplant patients. The aim of present study was to evaluate CMV viral load and laboratory findings correlation with CMV viremia graft origin and investigation on late or early onset CMV infection in kidney transplant recipients with CMV viremia. Methods: This research designed as a prospective case-control study based on CMV PCR test and exclusion of other viral infection among renal transplant patients in Iran.Results: From 192 examined patients, 153 participants were qualified to enter the study: 43 in case (with CMV viremia) and 110 in control group (CMV negative test). Statistical analysis performed to identify the risk factors raising this viral viremia among kidney transplant patients. Conclusion: Receiving a renal graft from a deceased donor significantly raise the chance of viremia in renal transplant patients. The median month of CMV viremia occurrence was month 4 after transplantation in both groups. Serum laboratory testing showed creatinine and platelets significantly raised and reduced, retrospectively in the case compare to control group. Our results indicating the viremia has not affected the survival of the allograft or patient.

scholarly journals Safety and Efficacy of Ferric Carboxymaltose in Anemic Pregnant Women: A Retrospective Case Control Study

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Anouk Pels ◽  
Wessel Ganzevoort
Keyword(s):  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Case Control Study ◽  
Case Control ◽  
Ferric Carboxymaltose ◽  
Control Group ◽  
Efficient Treatment ◽  
Safety And Efficacy ◽  
Anemia During Pregnancy ◽  
Control Study

Background. Anemia during pregnancy is commonly caused by iron deficiency and can have severe consequences for both the mother and the developing fetus. The aim of this retrospective study was to assess the safety and efficacy of intravenous ferric carboxymaltose (FCM) in pregnant women.Methods. All women treated with FCM for anemia during pregnancy between 2010 and 2012 at our institution were included. A matched control group was selected, including women who either were nonanemic or had anemia but were not considered for intravenous iron. Main outcome measures were maternal safety and pregnancy outcomes.Results. The study included 128 patients (FCM: 64; control: 64). Median FCM dose was 1000 mg and median gestational age at the time of first treatment was 34 weeks and 6 days. Median Hb increased from 8.4 g/dL (interquartile range 7.7; 8.9 g/dL) at the first FCM administration to 10.7 g/dL (9.8; 11.5 g/dL;n=46with available Hb at delivery) at the time of delivery, achieving levels similar to those in the control group (10.8 g/dL [9.8; 11.8 g/dL;n=48]). No treatment-related adverse events were reported and no statistically significant differences in pregnancy outcomes were observed between groups.Conclusions. Within the limitations of this case control study, FCM was a safe and efficient treatment of anemia during pregnancy.

scholarly journals Testicular shear wave elastography in oligo-astheno-teratozoospermic individuals: a prospective case–control study

2021 ◽  
Author(s):  
Ester Illiano ◽  
Francesco Trama ◽  
Antonio Ruffo ◽  
Giuseppe Romeo ◽  
Filippo Riccardo ◽  
...  
Keyword(s):  
Shear Wave ◽  
Case Control Study ◽  
Shear Wave Elastography ◽  
Case Control ◽  
Semen Parameters ◽  
Control Group ◽  
Group A ◽  
Group B ◽  
Control Study ◽  
Prospective Case Control Study

Abstract Purpose The primary objective of this study was to evaluate the testicular stiffness by ultrasound shear wave elastography (SWE) both in men with oligo-astheno-teratozospermia (OAT) and in control group. The secondary objective was to identify a possible correlation between semen quality with testicular stiffness. Methods This was a prospective case-control study. We divided the sample in two groups; Group A (case group) included men with OAT, and Group B (control group) men with normal sperm parameters. All participants had at last two semen analysis in the past 180 days (at last 90 days apart), using performed ultrasound and SWE elastography. Results We analyzed 100 participants, 50 patients in Group A and 50 controls in Group B. There were statistically significant differences in term of testicular volume and testicular stiffness between two groups. Men with OAT had the testicular stiffness value higher than the controls in both sides (left testicular stiffness 21.4 ± 5.4 kPa vs 9.9 ± 1.6 kPa, p < 0.0001; right testicular stiffness 22.9 ± 4.8 kPa vs 9.5 ± 2.4 kPa, p < 0.0001). Men with abnormal semen parameters showed an inverse correlation between the mean value of testicular stiffness and total sperm count (22.15 ± 3.38 kPa, r = − 0.387, p = 0.005), sperm concentration (22.15 ± 3.38 kPa, r = − 0.244, p = 0.04), and progressive motility (22.15 ± 3.38 kPa, r = − 0.336, p = 0.01), while the correlation was not evident in controls group. Conclusion SWE is able to differentiate between testicles with spermatogenic changes from a healthy testicle. For this reason, it could be used to evaluate, in a non-invasive way, the tissue alterations of the organ.

scholarly journals Impact of SARS-CoV-2 Infection During Pregnancy on Infant Neurobehavioral Development: A Case-Control Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Yao Cheng ◽  
Haoyue Teng ◽  
Yue Xiao ◽  
Mengxin Yao ◽  
Jieyun Yin ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Case Control Study ◽  
Statistical Significance ◽  
Case Control ◽  
Control Group ◽  
Neurobehavioral Development ◽  
Ages And Stages Questionnaires ◽  
Group 5 ◽  
Larger Sample ◽  
Control Study

Background: Previous studies on the pneumonia outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have focused on the general population and pregnant women, while little is known about the effects of SARS-CoV-2 on retardation during and after pregnancy. The purpose of this study was to evaluate the potential influence of SARS-CoV-2 on infant neurobehavioral development.Methods: A case-control study was conducted in Wuhan Maternal and Child Health Hospital, China. Nine pregnant women with SARS-CoV-2 infection and 9 controls matched by maternal age, parity, and status of chronic disease were included. Infantile neurobehavioral development was assessed through the Ages and Stages Questionnaires Edition 3 (ASQ-3).Results: The majority of pregnant women with SARS-CoV-2 experienced cesarean section (7 of 9), which was higher than the control group (5 of 9). The throat swabs of all newborn were negative. We found that compared with the control group, neonates of mothers with SARS-CoV-2 infection during pregnancy had lower scores in communication, gross movement, fine movement, problem solving, and personal-social domains; but only fine movement domain yielded statistical significance (P = 0.031).Conclusion: Infection with SARS-CoV-2 during pregnancy may have a certain impact on infant neurobehavioral development. Further studies with larger sample size are warranted for validation.

scholarly journals Sexual function in patients with endometriosis: a prospective case–control study in China

2021 ◽  
Vol 49 (4) ◽  
pp. 030006052110043
Author(s):  
Xiaochun Yang ◽  
Xinfen Xu ◽  
Lili Lin ◽  
Kaihong Xu ◽  
Min Xu ◽  
...  
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Function ◽  
Sexual Arousal ◽  
Case Control Study ◽  
Case Control ◽  
Sexual Life ◽  
Control Group ◽  
Sexual Pain ◽  
Control Study ◽  
Prospective Case Control Study

Objective Endometriosis is a common disease in women of childbearing age, leading to sexual dysfunction or loss of libido. We aimed to evaluated the effect of endometriosis on women’s sexual function. Methods We performed a prospective case–control study to determine the effect of endometriosis on women’s sexual function using a self-administered questionnaire from September 2017 to August 2018. The simplified Chinese version of the Female Sexual Function Index (FSFI) was used to assess sexual function. Results We found that sexual function of women in the endometriosis group (n=77) in all dimensions was significantly lower compared with that in the control group (n=63). The total FSFI score in patients was 25.5, which tended to be lower than that in the control group (26.7). Sexual arousal, sexual pain, and satisfaction were significantly different between the two groups. Sexual arousal and sexual pain scores were significantly lower in the endometriosis group than in the control group at the ages of 31 to 40 years. Conclusion Women with endometriosis suffer from sexual dysfunction, especially those aged 31 to 40 years. Our findings suggest that the quality of sexual life in this subpopulation needs to be improved.

scholarly journals Clinical Investigations: Lash Ptosis As A Characteristic Sign Of Floppy Eyelid Syndrome

Folia Medica ◽  
2014 ◽  
Vol 56 (3) ◽  
pp. 170-174 ◽  
Author(s):  
Milena I. Sredkova
Keyword(s):  
Clinical Sign ◽  
Case Control Study ◽  
Strong Association ◽  
Case Control ◽  
Control Group ◽  
Clinical Investigations ◽  
Eye Examination ◽  
Two Stages ◽  
Control Study ◽  
Prospective Case Control Study

ABSTRACT AIM: To find a correlation between the floppy eyelid syndrome and the clinical sign of lash ptosis and loss of eyelash parallelism and develop an algorithm for early diagnosis. MATERIALS AND METHODS: This is a prospective case-control study including 97 consecutive patients diagnosed with floppy eyelid and 81 healthy sex- and age-matched controls. The study was conducted in Professor Pashev Eye Hospital, Sofia between January 2011 and December 2012. The clinical sign of lash ptosis and loss of eyelash parallelism was investigated in two stages. The condition was graded using a specially designed algorithm. RESULTS: Lash ptosis and loss of eyelash parallelism was documented in all 97 (100%) patients with floppy eyelid and only in 8 patients (9%) in the control group. Statistical analysis of the results showed a very strong association between this sign and the floppy eyelid syndrome (p < 0.0001), and a correlation between the degree of lash ptosis and stage of the disease (p < 0.001). CONCLUSION: The clinical sign of lash ptosis and loss of eyelash parallelism is characteristic for the syndrome. Recognizing this sign during a routine eye examination can facilitate a timely diagnosis of the frequently overlooked and improperly treated disorder of floppy eyelid.

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