scholarly journals Three-dimensional femtosecond laser processing for lab-on-a-chip applications

Nanophotonics ◽  
2018 ◽  
Vol 7 (3) ◽  
pp. 613-634 ◽  
Author(s):  
Felix Sima ◽  
Koji Sugioka ◽  
Rebeca Martínez Vázquez ◽  
Roberto Osellame ◽  
Lóránd Kelemen ◽  
...  

AbstractThe extremely high peak intensity associated with ultrashort pulse width of femtosecond laser allows us to induce nonlinear interaction such as multiphoton absorption and tunneling ionization with materials that are transparent to the laser wavelength. More importantly, focusing the femtosecond laser beam inside the transparent materials confines the nonlinear interaction only within the focal volume, enabling three-dimensional (3D) micro- and nanofabrication. This 3D capability offers three different schemes, which involve undeformative, subtractive, and additive processing. The undeformative processing preforms internal refractive index modification to construct optical microcomponents including optical waveguides. Subtractive processing can realize the direct fabrication of 3D microfluidics, micromechanics, microelectronics, and photonic microcomponents in glass. Additive processing represented by two-photon polymerization enables the fabrication of 3D polymer micro- and nanostructures for photonic and microfluidic devices. These different schemes can be integrated to realize more functional microdevices including lab-on-a-chip devices, which are miniaturized laboratories that can perform reaction, detection, analysis, separation, and synthesis of biochemical materials with high efficiency, high speed, high sensitivity, low reagent consumption, and low waste production. This review paper describes the principles and applications of femtosecond laser 3D micro- and nanofabrication for lab-on-a-chip applications. A hybrid technique that promises to enhance functionality of lab-on-a-chip devices is also introduced.

2020 ◽  
Vol 8 (3) ◽  
pp. 257 ◽  
Author(s):  
Jinman Lv ◽  
Binbin Hong ◽  
Yang Tan ◽  
Feng Chen ◽  
Javier Rodríguez Vázquez de Aldana ◽  
...  

2020 ◽  
Vol 8 (6) ◽  
pp. 819 ◽  
Author(s):  
Zhoujie Wu ◽  
Wenbo Guo ◽  
Yueyang Li ◽  
Yihang Liu ◽  
Qican Zhang

2019 ◽  
Vol 1 (9) ◽  
pp. 3474-3484 ◽  
Author(s):  
Zhi Yu ◽  
Yuhao Lei ◽  
Weili Yu ◽  
Jinluo Cheng ◽  
Jun Xing ◽  
...  

A nanoporous array structure detection chip with strong spectral resolution, fabricated by femtosecond laser direct writing and anodized aluminum oxide.


2018 ◽  
Vol 232 ◽  
pp. 03051
Author(s):  
Mingxing Deng ◽  
Jian Mao ◽  
Xingwen Gan

With the rapid development of the logistics industry, high-speed, high-efficiency and accurate delivery have become the new pursuit goals of the logistics industry, and intelligent logistics has been favored by enterprises. Aiming at the current situation that the offline products must be manually moved, sorted and discharged, the scheme of fully automated three-dimensional warehouse is proposed. Through the design of the whole three-dimensional warehouse, the whole process of the offline products can be realized by AGV, AGV management system, warehouse management system and roller. Lines, palletizers, etc. are completed. As the core part of the whole solution, the warehouse management system plays a vital role in achieving point-to-point tracking of offline products, and can perform regular statistical analysis on the inbound and outbound products to achieve digital management, improve the competitiveness of enterprises and bring considerable economic benefits.


2020 ◽  
Vol 50 (1) ◽  
Author(s):  
Hyunung Yu

Abstract Scanning acoustic microscopy (SAM) or Acoustic Micro Imaging (AMI) is a powerful, non-destructive technique that can detect hidden defects in elastic and biological samples as well as non-transparent hard materials. By monitoring the internal features of a sample in three-dimensional integration, this technique can efficiently find physical defects such as cracks, voids, and delamination with high sensitivity. In recent years, advanced techniques such as ultrasound impedance microscopy, ultrasound speed microscopy, and scanning acoustic gigahertz microscopy have been developed for applications in industries and in the medical field to provide additional information on the internal stress, viscoelastic, and anisotropic, or nonlinear properties. X-ray, magnetic resonance, and infrared techniques are the other competitive and widely used methods. However, they have their own advantages and limitations owing to their inherent properties such as different light sources and sensors. This paper provides an overview of the principle of SAM and presents a few results to demonstrate the applications of modern acoustic imaging technology. A variety of inspection modes, such as vertical, horizontal, and diagonal cross-sections have been presented by employing the focus pathway and image reconstruction algorithm. Images have been reconstructed from the reflected echoes resulting from the change in the acoustic impedance at the interface of the material layers or defects. The results described in this paper indicate that the novel acoustic technology can expand the scope of SAM as a versatile diagnostic tool requiring less time and having a high efficiency.


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