Investigating the structural chemistry of organotin(IV) compounds: recent advances

AbstractOrganotin(IV) compounds have been considered for their outstanding industrial, medical and specific applications in the synthesis of various types of chemical compounds. In this review, we have focused on the structural chemistry of organotin(IV) compounds, including coordination chemistry, the effect of structure on reactions, bond formations from the perspective of structure and investigation of the structure of organotin(IV) compounds in different phases. The structural chemistry of organotin(IV) compounds is subject to interest due to their major impact on predicting the properties and drumming up support for pushing back the frontiers of synthesis of organotin(IV) compounds with advanced properties.

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Recent Advances in Structural Chemistry of Organic Germanium, Tin and Lead Compounds

The Chemistry of Organic Germanium, Tin and Lead Compounds - The Chemistry of Functional Groups ◽

10.1002/0470857188.ch4 ◽

2003 ◽

pp. 283-357 ◽

Cited By ~ 16

Author(s):

Karl W. Klinkhammer

Keyword(s):

Structural Chemistry ◽

Lead Compounds ◽

Recent Advances ◽

Germanium Tin

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Recent Advances in Cell Penetrating Peptide-Based Anticancer Therapies

Molecules ◽

10.3390/molecules24050927 ◽

2019 ◽

Vol 24 (5) ◽

pp. 927 ◽

Cited By ~ 61

Author(s):

Justine Habault ◽

Jean-Luc Poyet

Keyword(s):

Tissue Specificity ◽

Chemical Compounds ◽

Drug Carriers ◽

Cell Penetrating Peptides ◽

Amino Acid Sequences ◽

Recent Advances ◽

Cell Penetrating ◽

A Cell ◽

Low Toxicity ◽

Applied Biology

Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their ability to cross cellular membranes. They can transport various bioactive cargos inside cells including nucleic acids, large proteins, and other chemical compounds. Since 1988, natural and synthetic CPPs have been developed for applications ranging from fundamental to applied biology (cell imaging, gene editing, therapeutics delivery). In recent years, a great number of studies reported the potential of CPPs as carriers for the treatment of various diseases. Apart from a good efficacy due to a rapid and potent delivery, a crucial advantage of CPP-based therapies is the peptides low toxicity compared to most drug carriers. On the other hand, they are quite unstable and lack specificity. Higher specificity can be obtained using a cell-specific CPP to transport the therapeutic agent or using a non-specific CPP to transport a cargo with a targeted activity. CPP-cargo complexes can also be conjugated to another moiety that brings cell- or tissue-specificity. Studies based on all these approaches are showing promising results. Here, we focus on recent advances in the potential usage of CPPs in the context of cancer therapy, with a particular interest in CPP-mediated delivery of anti-tumoral proteins.

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Most Recent Advances in Diesel Engine Catalytic Soot Abatement: Structured Catalysts and Alternative Approaches

Catalysts ◽

10.3390/catal10070745 ◽

2020 ◽

Vol 10 (7) ◽

pp. 745 ◽

Cited By ~ 1

Author(s):

Eugenio Meloni ◽

Vincenzo Palma

Keyword(s):

Diesel Engine ◽

Solid Phase ◽

Chemical Compounds ◽

Active Species ◽

Wire Mesh ◽

Engine Emissions ◽

Structured Catalysts ◽

Geometric Configurations ◽

Recent Advances ◽

Alternative Approaches

Diesel engine emissions are typically composed of several hundred chemical compounds, partly present in the gas phase and partly in solid phase as particles, the so-called particulate matter or soot. The morphology of the catalyst is an important characteristic of soot particles’ abatement, since a good contact between catalyst and soot is mandatory. For practical purposes, the active species should be supported as a film on the structured carrier, in order to allow simultaneous soot filtration and combustion. This review focuses on the most recent advances in the development of structured catalysts for diesel engine catalytic soot combustion, characterized by different active species and supports, as well as by different geometric configurations (monoliths, foams, ceramic papers, or wire mesh); the most important peculiar properties are highlighted and summarized. Moreover, a critical review of the most recent advances in modeling studies is also presented in this paper. In addition, some highlights on some of the most recent alternative approaches proposed for limiting the soot emissions from diesel engines have been given, delineating feasible alternatives to the classical strategies nowadays used.

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