Pancreatic cancer: gene therapy approaches and gene delivery systems

2009 ◽  
Vol 10 (1) ◽  
pp. 73-88 ◽  
Author(s):  
Jin Xu ◽  
Chen Jin ◽  
Sijie Hao ◽  
Guopei Luo ◽  
Deliang Fu
Keyword(s):  
Pancreatic Cancer ◽  
Gene Therapy ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Delivery Systems ◽  
Cancer Gene

scholarly journals Pancreatic Cancer Gene Therapy: From Molecular Targets to Delivery Systems

Cancers ◽  
2011 ◽  
Vol 3 (1) ◽  
pp. 368-395 ◽  
Author(s):  
Cristina Fillat ◽  
Anabel Jose ◽  
Xavier Bofill-De Ros ◽  
Ana Mato-Berciano ◽  
Maria Victoria Maliandi ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Gene Therapy ◽  
Molecular Targets ◽  
Cancer Gene Therapy ◽  
Delivery Systems ◽  
Cancer Gene

scholarly journals Light-induced adenovirus gene transfer, an efficient and specific gene delivery technology for cancer gene therapy

2002 ◽  
Vol 9 (4) ◽  
pp. 365-371 ◽  
Author(s):  
Anders Høgset ◽  
Birgit Øvstebø Engesæter ◽  
Lina Prasmickaite ◽  
Kristian Berg ◽  
Øystein Fodstad ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Transfer ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Specific Gene ◽  
Cancer Gene ◽  
Delivery Technology

scholarly journals Delivery systems of CRISPR/Cas9-based cancer gene therapy

2018 ◽  
Vol 12 (1) ◽  
Author(s):  
Alessio Biagioni ◽  
Anna Laurenzana ◽  
Francesca Margheri ◽  
Anastasia Chillà ◽  
Gabriella Fibbi ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Cancer Gene Therapy ◽  
Delivery Systems ◽  
Cancer Gene

scholarly journals Publisher Correction to: delivery systems of CRISPR/Cas9-based cancer gene therapy

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Alessio Biagioni ◽  
Anna Laurenzana ◽  
Francesca Margheri ◽  
Anastasia Chillà ◽  
Gabriella Fibbi ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Cancer Gene Therapy ◽  
Delivery Systems ◽  
Cancer Gene

scholarly journals Heat-induced transcription of diphtheria toxin A or its variants, CRM176 and CRM197: implications for pancreatic cancer gene therapy

2009 ◽  
Vol 17 (1) ◽  
pp. 58-68 ◽  
Author(s):  
P Fogar ◽  
F Navaglia ◽  
D Basso ◽  
C-F Zambon ◽  
L Moserle ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Gene Therapy ◽  
Diphtheria Toxin ◽  
Cancer Gene Therapy ◽  
Cancer Gene ◽  
Toxin A ◽  
Diphtheria Toxin A

scholarly journals Transcriptional Targeting in Cancer Gene Therapy

2003 ◽  
Vol 2003 (2) ◽  
pp. 110-137 ◽  
Author(s):  
Tracy Robson ◽  
David G. Hirst
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Cancer Gene ◽  
Cancer Treatments ◽  
Transcriptional Targeting ◽  
Exogenous Agents ◽  
Therapeutic Research ◽  
Systemic Gene Delivery ◽  
Near Future

Cancer gene therapy has been one of the most exciting areas of therapeutic research in the past decade. In this review, we discuss strategies to restrict transcription of transgenes to tumour cells. A range of promoters which are tissue-specific, tumour-specific, or inducible by exogenous agents are presented. Transcriptional targeting should prevent normal tissue toxicities associated with other cancer treatments, such as radiation and chemotherapy. In addition, the specificity of these strategies should provide improved targeting of metastatic tumours following systemic gene delivery. Rapid progress in the ability to specifically control transgenes will allow systemic gene delivery for cancer therapy to become a real possibility in the near future.

scholarly journals Recent Advances in the Development of Bio-Reducible Polymers for Efficient Cancer Gene Delivery Systems

2019 ◽  
Vol 2 (1) ◽  
pp. 6-13 ◽  
Author(s):  
Kiel Sung Yong ◽  
◽  
Wan Kim Sung ◽  
◽  
◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Ribonucleic Acid ◽  
Viral Vectors ◽  
Delivery Systems ◽  
Host Cells ◽  
Viral Gene ◽  
Cancer Gene ◽  
Inherited Disorders ◽  
Messenger Ribonucleic Acid

Gene therapy is the unique method for the use of genetic materials such as Messenger ribonucleic acid (mRNA), plasmid deoxyribonucleic acid (pDNA), and small interfering ribonucleic acid (siRNA) into specific host-cells for the treatment of inherited disorders in any diseases. The successful way to utilize the gene therapy is to develop the efficient cancer gene delivery systems. In this paper, the successful and efficient gene delivery systems are briefly reviewed on the basis of bio-reducible polymeric systems for cancer therapy. The viral gene delivery systems such as RNA-based viral and DNA-based viral vectors are also discussed. The development of bio-reducible polymer for gene delivery system has briefly discussed for the efficient cancer gene delivery of viral vectors and non-viral vectors.

Sign in / Sign up

Export Citation Format

Share Document