Strength training is capable of stimulating transcription factors Runx2 and osterix and ensure better bone quality in wistar rats during aging

2014 ◽  
Author(s):  
Camila Tami Stringhetta-Garcia ◽  
Edilson Ervolino ◽  
Ana Claudia Rossi ◽  
Mario Jefferson Quirino Louzada ◽  
Mello Wagner Garcez de ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Strength Training ◽  
Bone Quality ◽  
Wistar Rats

scholarly journals Association between Visceral and Bone Marrow Adipose Tissue and Bone Quality in Sedentary and Physically Active Ovariectomized Wistar Rats

Life ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 478
Author(s):  
Hélder Fonseca ◽  
Andrea Bezerra ◽  
Ana Coelho ◽  
José Alberto Duarte
Keyword(s):  
Physical Activity ◽  
Bone Marrow ◽  
Adipose Tissue ◽  
Bone Mass ◽  
Bone Quality ◽  
Wistar Rats ◽  
Biomechanical Properties ◽  
Physically Active ◽  
Bone Formation Rate ◽  
Marrow Adiposity

Background: Obesity is considered protective for bone mass, but this view has been progressively challenged. Menopause is characterized by low bone mass and increased adiposity. Our aim was to determine how visceral and bone marrow adiposity change following ovariectomy (OVX), how they correlate with bone quality and if they are influenced by physical activity. Methods: Five-month-old Wistar rats were OVX or sham-operated and maintained in sedentary or physically active conditions for 9 months. Visceral and bone marrow adiposity as well as bone turnover, femur bone quality and biomechanical properties were assessed. Results: OVX resulted in higher weight, visceral and bone marrow adiposity. Visceral adiposity correlated inversely with femur Ct.Th (r = −0.63, p < 0.001), BV/TV (r = −0.67, p < 0.001), Tb.N (r = −0.69, p < 0.001) and positively with Tb.Sp (r = 0.58, p < 0.001). Bone marrow adiposity also correlated with bone resorption (r = 0.47, p < 0.01), bone formation rate (r = −0.63, p < 0.01), BV/TV (r = −0.85, p < 0.001), Ct.Th (r = −0.51, p < 0.0.01), and with higher empty osteocyte lacunae (r = 0.39, p < 0.05), higher percentage of osteocytes with oxidative stress (r = 0.64, p < 0.0.01) and lower femur maximal stress (r = −0.58, p < 0.001). Physical activity correlated inversely with both visceral (r = −0.74, p < 0.01) and bone marrow adiposity (r = −0.92, p < 0.001). Conclusions: OVX increases visceral and bone marrow adiposity which are associated with inferior bone quality and biomechanical properties. Physical activity could contribute to reduce adipose tissue and thereby improve bone quality.

scholarly journals Use of the anabolic steroid nandrolone decanoate associated to strength training in Wistar rats

2013 ◽  
Vol 35 (2) ◽  
pp. 283-291 ◽  
Author(s):  
Leonardo Vidal Andreato ◽  
João Victor Del Conti Esteves ◽  
Felipe Natali Almeida ◽  
Tatiane Aparecida da Silva Ribeiro ◽  
Helenton Cristhian Barrena ◽  
...  
Keyword(s):  
Strength Training ◽  
Anabolic Steroid ◽  
Wistar Rats ◽  
Nandrolone Decanoate

scholarly journals Influence of clenbuterol on bone metabolism in exercised or sedentary rats

2002 ◽  
Vol 93 (6) ◽  
pp. 2034-2037 ◽  
Author(s):  
H. Cavalié ◽  
G. Lac ◽  
P. Lebecque ◽  
B. Chanteranne ◽  
M.-J. Davicco ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Strength Training ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Fat Mass ◽  
Lean Mass ◽  
Wistar Rats ◽  
Exercise Program ◽  
Mineral Density ◽  
Training Exercise

This paper reports that the selective β2-adrenergic receptor agonist clenbuterol affects bone metabolism in growing 3-mo-old male Wistar rats treated over 8 wk. Thirty-two 3-mo-old growing Wistar rats weighing 234 ± 2 g were assigned to a progressive isometric force, strength-training exercise program plus oral clenbuterol (2 mg · kg body wt−1 · day−1) for 5 days each week, exercise program without clenbuterol 5 days each week, no exercise program plus oral clenbuterol (2 mg · kg−1 · day−1) for 5 days each week, or no exercise without clenbuterol 5 days each week. At the end of 8 wk, lean mass, fat mass, and right total femoral, distal metaphyseal femoral, and diaphyseal femoral bone mineral density were measured by Hologic QDR 4500 dual X-ray absorptiometry (DEXA) technique. Left femoral bones were harvested after death on day 58, and femoral resistance was determined by three-point bending testing. We found that fat mass was decreased in rats given strength training exercise and decreased further in rats treated with clenbuterol. Lean mass was increased in clenbuterol-treated animals. Strength-training exercise appeared to have no effect on bone mineral density, serum osteocalcin, or urinary deoxypyridinoline. However, clenbuterol treatment decreased femoral length, diameter, bone mineral density, and mechanical resistance. Clenbuterol had no effect on osteocalcin but increased urinary deoxypyridinoline. We concluded that clenbuterol treatment decreased bone mineral density and increased bone resorption independent of the level of exercise rats were given.

Strength training reduces lipid accumulation in liver of obese Wistar rats

Life Sciences ◽  
2019 ◽  
Vol 235 ◽  
pp. 116834 ◽  
Author(s):  
Giulia Fonseca dos Santos ◽  
Allice Santos Cruz Veras ◽  
Marcelo Conrado de Freitas ◽  
James McCabe ◽  
Patrícia Monteiro Seraphim ◽  
...  
Keyword(s):  
Strength Training ◽  
Lipid Accumulation ◽  
Wistar Rats

scholarly journals Muscle Strength Training is Better than the Use of Growth Hormone (GH) in Bone Health of Wistar Rats

2019 ◽  
Vol 37 (1) ◽  
pp. 104-110
Author(s):  
Heliard Rodrigues dos Santos Caetano ◽  
Robson Chacon Castoldi ◽  
Éverton Alex Carvalho Zanuto ◽  
Guilherme Akio Tamura Ozaki ◽  
Thiago Alves Garcia ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Muscle Strength ◽  
Strength Training ◽  
Bone Health ◽  
Wistar Rats ◽  
Better Than

scholarly journals Effects of strength training and raloxifene on femoral neck metabolism and microarchitecture of aging female Wistar rats

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Camila Tami Stringhetta-Garcia ◽  
Samuel Rodrigues Lourenço Morais ◽  
Fernanda Fernandes ◽  
Melise Jacon Perez-Ueno ◽  
Ricardo de Paula Almeida ◽  
...  
Keyword(s):  
Femoral Neck ◽  
Strength Training ◽  
Wistar Rats ◽  
Female Wistar Rats

scholarly journals Chronic isometric strength training reduces anxiety‐like behavior in Wistar rats (684.15)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Rodrigo Conceicao ◽  
Roberto Laureano‐Melo ◽  
Claudio Almeida ◽  
Guilherme Pinto ◽  
Wellington Cortes
Keyword(s):  
Strength Training ◽  
Wistar Rats ◽  
Isometric Strength

Bone quality is associated with perinatal nutritional manipulation in adult Wistar rats offspring

2020 ◽  
Author(s):  
Areti Augoulea ◽  
Nikolaos Syggelos ◽  
Eleni Armeni ◽  
George Kaparos ◽  
Homeira Vafaei ◽  
...  
Keyword(s):  
Bone Quality ◽  
Wistar Rats

Strength training and growth hormone: effects on bone of Wistar rats

2021 ◽  
Author(s):  
Robson Chacon Castoldi ◽  
Ines Cristina Giometti ◽  
Guilherme Akio Tamura Ozaki ◽  
Thiago Alves Garcia ◽  
Melise Jacon Peres Ueno ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Strength Training ◽  
Wistar Rats ◽  
Hormone Effects
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