Gender specific paediatric reference data for muscle function parameters assessed using jumping mechanography

2019 ◽  
Author(s):  
Sonal Palande ◽  
Veena Ekbote ◽  
Shashi Chiplonkar ◽  
Raja Padidela ◽  
Zulf Mughal ◽  
...  
Keyword(s):  
Muscle Function ◽  
Reference Data ◽  
Jumping Mechanography ◽  
Gender Specific

Production of gender-specific morning salivary cortisol reference intervals using internationally accepted procedures

2004 ◽  
Vol 42 (12) ◽  
Author(s):  
Rajan S. Patel ◽  
Steve R. Shaw ◽  
Halena MacIntyre ◽  
Gerald W. McGarry ◽  
A. Michael Wallace
Keyword(s):  
Salivary Cortisol ◽  
Reference Data ◽  
Clinical Chemistry ◽  
Reference Intervals ◽  
International Federation ◽  
Adrenal Function ◽  
Biologically Active ◽  
Males And Females ◽  
Gender Specific ◽  
Free Plasma

AbstractBackground: Salivary cortisol concentrations correlate well with biologically active unbound free plasma cortisol concentrations. Despite its practical and analytical advantages, salivary cortisol measurement has been used mainly as a research tool rather than for the routine evaluation of adrenal function. This may be partly explained by the lack of robust reference data in the literature.Methods: Using the recommended procedures for the production of reference intervals published by the International Federation of Clinical Chemistry, we aimed to produce morning salivary cortisol reference intervals for males and females. Salivary cortisol was measured in 496 specimens collected from 248 reference individuals (128 males, median age 41years, range 16–86; and 120 females, median age 44years, range 16–98) attending an otorhinolaryngology clinic. Reference individuals mailed saliva specimens sampled on two consecutive mornings to our laboratory, where cortisol concentrations were measured.Results: Statistical analysis showed no significant correlation with age or body mass index. The following 95% gender-partitioned reference intervals were produced: males 10.9–40.3nmol/l; and females 9.3–40.3nmol/l.Conclusion: Knowledge of these salivary cortisol reference intervals helps us monitor the adrenal function of outpatients using topical intranasal glucocorticoids for rhinosinusitis.

scholarly journals The Impact of Low Muscle Mass Definition on the Prevalence of Sarcopenia in Older Australians

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Solomon Yu ◽  
Sarah Appleton ◽  
Robert Adams ◽  
Ian Chapman ◽  
Gary Wittert ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Older People ◽  
Muscle Mass ◽  
Muscle Function ◽  
Reference Population ◽  
Skeletal Mass ◽  
The Impact ◽  
Gender Specific ◽  
Linear Regressions ◽  
Mass Definition

Background.Sarcopenia is the presence of low muscle mass and low muscle function. The aim of this study was to establish cutoffs for low muscle mass using three published methods and to compare the prevalence of sarcopenia in older Australians.Methods.Gender specific cutoffs levels were identified for low muscle mass using three different methods. Low grip strength was determined using established cutoffs of <30 kg for men and <20 kg for women to estimate the prevalence of sarcopenia.Results.Gender specific cutoffs levels for low muscle mass identified were (a) <6.89 kg/m2for men and <4.32 kg/m2for women, <2 standard deviation (SD) of a young reference population; (b) <7.36 kg/m2for men and <5.81 kg/m2for women from the lowest 20% percentile of the older group; and (c) <−2.15 for men and <−1.42 for women from the lowest 20% of the residuals of linear regressions of appendicular skeletal mass, adjusted for fat mass and height. Prevalence of sarcopenia in older (65 years and older) people by these three methods for men was 2.5%, 6.2%, and 6.4% and for women 0.3%, 9.3%, and 8.5%, respectively.Conclusions.Sarcopenia is common but consensus on the best method to confirm low muscle mass is required.

Reproducibility of jumping mechanography and traditional measures of physical and muscle function in older adults

2014 ◽  
Vol 26 (2) ◽  
pp. 819-825 ◽  
Author(s):  
B. Buehring ◽  
D. Krueger ◽  
E. Fidler ◽  
R. Gangnon ◽  
B. Heiderscheit ◽  
...  
Keyword(s):  
Older Adults ◽  
Muscle Function ◽  
Jumping Mechanography

scholarly journals Association of Jumping Mechanography-Derived Indices of Muscle Function with Tibial Cortical Bone Geometry

2015 ◽  
Vol 98 (5) ◽  
pp. 446-455 ◽  
Author(s):  
Charlotte Verroken ◽  
Hans-Georg Zmierczak ◽  
Stefan Goemaere ◽  
Jean-Marc Kaufman ◽  
Bruno Lapauw
Keyword(s):  
Cortical Bone ◽  
Muscle Function ◽  
Bone Geometry ◽  
Cortical Bone Geometry ◽  
Jumping Mechanography ◽  
Tibial Cortical Bone

Jumping Mechanography and Classic Muscle Function Tests: Effects of Age and Gender

2012 ◽  
Vol 15 (4) ◽  
pp. 482-483
Author(s):  
Ellen Fidler ◽  
Bjoern Buehring ◽  
Jessie Libber ◽  
Mary Checovich ◽  
Diane Krueger ◽  
...  
Keyword(s):  
Muscle Function ◽  
Age And Gender ◽  
Function Tests ◽  
And Gender ◽  
Jumping Mechanography

scholarly journals Influence of aging and long-term unloading on the structure and function of human skeletal muscleThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

2009 ◽  
Vol 34 (3) ◽  
pp. 459-464 ◽  
Author(s):  
Todd Trappe
Keyword(s):  
Skeletal Muscle ◽  
Muscle Function ◽  
Peer Review Process ◽  
Qualitative Change ◽  
Skeletal Muscle Function ◽  
Aging Men ◽  
And Gender ◽  
And Function ◽  
Gender Specific ◽  
Qualitative Changes

Understanding the quantitative and qualitative changes in skeletal muscle that control changes in function is crucial in the development of countermeasures to the loss of skeletal muscle function observed with real and simulated microgravity exposure (i.e., unloading) and with aging in humans. Qualitative changes that could influence the force and power producing properties of skeletal muscle are changes in the distribution of the 3 isoforms of the main motor protein myosin heavy chain (MHC), as well as the abundance of MHC, actin (the other main contractile protein), and the force distributing the connective tissue network. Numerous studies have examined quantitative and qualitative changes in skeletal muscle, from the whole muscle to the single myofiber from individuals undergoing real and simulated space flight for a few weeks to several months, as well as from aging men and women. When considering the relative content of the main functional and structural elements (i.e., myosin, actin, collagen), it appears that human muscle appropriately scales changes in size of 10%–40% induced over a relatively short time period (1–3 months) and over the lifespan (in humans 20 to 90+ years old). The main qualitative change with unloading and aging is a redistribution of the 3 MHC isoforms, which have vastly different contractile characteristics. It is now known that the response of skeletal muscle to unloading is muscle and gender specific. In summary, changes in muscle mass (quantity) combined with the alterations in MHC distribution (quality) are the primary determinants of changes in muscle function with unloading and aging. These parameters are the key components of muscle that should be targeted with countermeasures for conditions related to muscle loss, along with considerations for muscle- and gender-specific responses.

scholarly journals Gender‐Specific Pulmonary Hypertension and Altered Skeletal Muscle Function in Lung‐Specific TNFα Overexpressing Mice

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Kechun Tang ◽  
Yusu Gu ◽  
Nancy Dalton ◽  
Kirk Peterson ◽  
Peter D. Wagner ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Pulmonary Hypertension ◽  
Muscle Function ◽  
Skeletal Muscle Function ◽  
Gender Specific

Clausal Density Between Ages 4 and 9 Years for the Edmonton Narrative Norms Instrument: Reference Data and Psychometric Properties

2020 ◽  
pp. 1-15
Author(s):  
Ling-Yu Guo ◽  
Phyllis Schneider ◽  
William Harrison
Keyword(s):  
Diagnostic Accuracy ◽  
Psychometric Properties ◽  
Language Impairment ◽  
Reference Data ◽  
Reliability And Validity ◽  
Correlation Coefficients ◽  
Criterion Validity ◽  
Likelihood Ratios ◽  
Generation Task ◽  
Sensitivity Specificity

Purpose This study provided reference data and examined psychometric properties for clausal density (CD; i.e., number of clauses per utterance) in children between ages 4 and 9 years from the database of the Edmonton Narrative Norms Instrument (ENNI). Method Participants in the ENNI database included 300 children with typical language (TL) and 77 children with language impairment (LI) between the ages of 4;0 (years;months) and 9;11. Narrative samples were collected using a story generation task, in which children were asked to tell stories based on six picture sequences. CD was computed from the narrative samples. The split-half reliability, concurrent criterion validity, and diagnostic accuracy were evaluated for CD by age. Results CD scores increased significantly between ages 4 and 9 years in children with TL and those with LI. Children with TL produced higher CD scores than those with LI at each age level. In addition, the correlation coefficients for the split-half reliability and concurrent criterion validity of CD scores were all significant at each age level, with the magnitude ranging from small to large. The diagnostic accuracy of CD scores, as revealed by sensitivity, specificity, and likelihood ratios, was poor. Conclusions The finding on diagnostic accuracy did not support the use of CD for identifying children with LI between ages 4 and 9 years. However, given the attested reliability and validity for CD, reference data of CD from the ENNI database can be used for evaluating children's difficulties with complex syntax and monitoring their change over time. Supplemental Material https://doi.org/10.23641/asha.13172129

Sign in / Sign up

Export Citation Format

Share Document