scholarly journals Role of receptors for epidermal growth factor and insulin-like growth factors I and II in the differentiation of rat mammary glands from lactogenesis I to lactogenesis II

Reproduction ◽  
1996 ◽  
Vol 107 (2) ◽  
pp. 307-314 ◽  
Author(s):  
L. E. Bussmann ◽  
I. M. Bussmann ◽  
E. H. Charreau
Keyword(s):  
Growth Factors ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Mammary Glands ◽  
Epidermal Growth ◽  
Insulin Like Growth Factors

Effect of pregestational sialoadenectomy of nursing mothers on eyelid opening of pups

1985 ◽  
Vol 249 (3) ◽  
pp. R285-R289
Author(s):  
S. Okamoto ◽  
T. Oka
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Submandibular Gland ◽  
Mammary Glands ◽  
Submandibular Glands ◽  
Nursing Mothers ◽  
Pregnant Mice ◽  
Epidermal Growth

The eyelid opening of pups born to and nursed by normal mice occurred by the 15th day of birth, whereas pregestational sialoadenectomy (removal of submandibular glands) of nursing mice delayed eyelid opening of their pups by as much as 5 days. Parotidectomy, however, had no effect on eyelid opening. Cross-foster nursing experiments indicated that the cause for delayed eyelid opening of pups was to be found in sialoadenectomized mothers, not their pups. Sialoadenectomized mothers had underdeveloped mammary glands that produced approximately 50% less milk than controls, and the amount of epidermal growth factor in their milk was similarly reduced. When epidermal growth factor, a polypeptide produced by the submandibular gland, was injected daily at a dose of 5 micrograms into sialoadenectomized pregnant mice, the eyelid opening of the pups nursed by their mothers occurred normally. These results are discussed with regard to the possible role of the submandibular gland and epidermal growth factor in neonatal eyelid opening.

Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor

Nature ◽  
1984 ◽  
Vol 310 (5980) ◽  
pp. 781-784 ◽  
Author(s):  
Jane E. Brissenden ◽  
Axel Ullrich ◽  
Uta Francke
Keyword(s):  
Growth Factors ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Chromosomal Mapping ◽  
Epidermal Growth ◽  
Insulin Like Growth Factors

scholarly journals Growth Factors in Human Pancreatic Cancer: Update on the Role of the Epidermal Growth Factor Receptor

1994 ◽  
Vol 11 (3-6) ◽  
pp. 147-149 ◽  
Author(s):  
Murray Korc ◽  
Helmut Friess ◽  
Michael S. Kobrin ◽  
Matthias Ebert ◽  
Markus W. Büchler
Keyword(s):  
Pancreatic Cancer ◽  
Epidermal Growth Factor Receptor ◽  
Growth Factors ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Growth Factor Receptor ◽  
Human Pancreatic Cancer ◽  
Epidermal Growth
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