A Study on Clinical Presentations of Oral Cancer at Tertiary Care Hospital, Bellary, Karnataka

Introduction: This study was conducted to evaluate the clinical presentations and management of various Orbito-ocular malignancies in Nepal. Materials and methods: This is a prospective study of ocular malignant cases conducted at a tertiary care eye hospital in Kathmandu, Nepal. One hundred and seventeen newly diagnosed eyes with ocular malignancy of 106 patients presenting to the clinic in a year from September 2018 to August 2019 were included for analysis. Patients’ demography, clinical features, various types of malignancies seen in eyes and their management were evaluated. Results: The mean age of patients was 30.35 years with a range from 1 month to 84 years and standard deviation of 26.63. 56% of the total were male. Red eyes and visible mass were the most common symptoms in 23% with intraocular contents in 48% being the most common site involved. Different types of ocular malignancies were detected, among which retinoblastoma was the most common in 38% of patients. Diagnosis in most patients was clinical and/or radiological; incision biopsy was required in 1.7% patients only. Surgical excision of the tumor was the most common treatment done in 29% followed by enucleation in 27% of eyes. Bilateral involvement of the eyes was seen in 10% of the patients. Conclusion: Malignant orbito-ocular tumors can be seen in any age group. Retinoblastoma is the commonest malignancy seen. With the help of imaging, diagnosis is near accurate; hence biopsy is not required in most cases before commencing treatment.

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Risk Factors and Costs of Oral Cancer in a Tertiary Care Hospital in Delhi

Asian Pacific Journal of Cancer Prevention ◽

10.7314/apjcp.2014.15.4.1659 ◽

2014 ◽

Vol 15 (4) ◽

pp. 1659-1665 ◽

Cited By ~ 11

Author(s):

Sandeep Goyal ◽

Vijay Kumar Tiwari ◽

Kesavan Sreekantan Nair ◽

Sherin Raj

Keyword(s):

Risk Factors ◽

Oral Cancer ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital

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Clinical manifestations of nocardiosis: Study of risk factors and outcomes in a tertiary care hospital

Journal of Laboratory Physicians ◽

10.4103/jlp.jlp_111_16 ◽

2017 ◽

Vol 9 (04) ◽

pp. 288-295 ◽

Cited By ~ 1

Author(s):

Teena Wadhwa ◽

Usha Baveja ◽

Navin Kumar ◽

Deepak Govil ◽

Sharmila Sengupta

Keyword(s):

Risk Factors ◽

Retrospective Analysis ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Clinical Manifestations ◽

Immunosuppressive Drugs ◽

Care Hospital ◽

Immunocompromised Patients ◽

Radiological Findings ◽

Clinical Presentations

Abstract PURPOSE: The aim of this study is to evaluate the predisposing risk factors, clinical presentations, laboratory parameters, and treatments taken and outcomes in patients of nocardiosis in the span of 5 years in a tertiary care hospital. MATERIALS AND METHODS: The patients whose specimens showed Nocardia like organism in Gram-staining, Kinyoun staining and characteristic colonies in culture were included in the retrospective analysis study. Retrospective analysis of associated risk factors, clinical presentations, and radiological findings was performed. RESULTS: Of the thirteen patients, 11 (76.9%) had immunosuppressive pathologies including solid organ transplantation, autoimmune disease, use of steroids, and immunosuppressive drugs as important risk factors. Four types of clinical manifestations were observed, pulmonary (46.1%), cutaneous (23.07%), cerebral (15.3%), and bacteremia (15.3%). The most common presentation was pulmonary with steroid therapy as a significant risk factor. Consolidation and pleural effusion were the common radiological findings in these cases. In eight of the nine patients anti-nocrdial drugs were given. Cotrimoxazole as monotherapy was given in four cases (44.44%), cotrimoxazole in combination with meropenem in two cases (22.22%); minocycline and linezolid were given in one case each. The overall mortality was 36.36% and was seen in patients with pulmonary nocardiosis. CONCLUSIONS: The study indicates that Nocardial infections are re-emerging on account of an increase in numbers of immunocompromised patients due to increased organ transplants, autoimmune diseases, malignancies, and use of immunosuppressive drugs and steroids. The diagnosis is often missed/not suspected and delayed because of the clinical resemblance to many other infections. Nocardial infection should be suspected and assessed particularly in immunocompromised patients not responding to treatment/improving clinically.

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Factors Associated with Perforated Appendicitis in Elderly Patients in a Tertiary Care Hospital

Surgery Research and Practice ◽

10.1155/2015/847681 ◽

2015 ◽

Vol 2015 ◽

pp. 1-6 ◽

Cited By ~ 4

Author(s):

Siripong Sirikurnpiboon ◽

Suparat Amornpornchareon

Keyword(s):

Acute Appendicitis ◽

Elderly Patients ◽

Medical Records ◽

Tertiary Care Hospital ◽

Demographic Data ◽

Tertiary Care ◽

Perforated Appendicitis ◽

Care Hospital ◽

Clinical Presentations ◽

Perforation Group

Background. The incidence of perforated appendicitis in elderly patients is high and carries increased morbidity and mortality rates. The aim of this study was to identify risk factors of perforation in elderly patients who presented with clinical of acute appendicitis.Methods. This was a retrospective study, reviewing medical records of patients over the age of 60 years who had a confirmed diagnosis of acute appendicitis. Patients were classified into two groups: those with perforated appendicitis and those with nonperforated appendicitis. Demographic data, clinical presentations, and laboratory analysis were compared.Results. Of the 206 acute appendicitis patients over the age of 60 years, perforated appendicitis was found in 106 (50%) patients. The four factors which predicted appendiceal rupture were as follows: male; duration of pain in preadmission period; fever (>38°C); and anorexia. The overall complication rate was 34% in the perforation group and 12.6% in the nonperforation group.Conclusions. The incidence of perforated appendicitis in elderly patients was higher in males and those who had certain clinical features such as fever and anorexia. Duration of pain in the preadmission period was also an important factor in appendiceal rupture. Early diagnosis may decrease the incidence of perforated appendicitis in elderly patients.

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