Nasopharyngeal carcinoma: Current treatment options and future directions

2014 ◽  
Author(s):  
Saad Shumaila ◽  
◽  
Wang Tony J. C ◽  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Treatment Options ◽  
Current Treatment ◽  
Future Directions

scholarly journals Current Treatment Options for Local Residual Nasopharyngeal Carcinoma

2013 ◽  
Vol 14 (4) ◽  
pp. 475-491 ◽  
Author(s):  
S. D. Stoker ◽  
J. N. A. van Diessen ◽  
J. P. de Boer ◽  
B. Karakullukcu ◽  
C. R. Leemans ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Treatment Options ◽  
Current Treatment

scholarly journals The next decade of clinical trials in locoregionally advanced nasopharyngeal carcinoma

2019 ◽  
Vol 92 (1102) ◽  
pp. 20181031 ◽  
Author(s):  
Liang Peng ◽  
Jin-Qi Liu ◽  
Yu-Pei Chen ◽  
Jun Ma
Keyword(s):  
Clinical Trials ◽  
Nasopharyngeal Carcinoma ◽  
Concurrent Chemoradiotherapy ◽  
Current Treatment ◽  
Treatment Modalities ◽  
Future Research ◽  
Future Directions ◽  
Barr Virus ◽  
The Past ◽  
Epstein Barr

Clinical trials are powerful weapons in the battle against nasopharyngeal carcinoma (NPC). Based on clinical trials conducted in the past two decades, concurrent chemoradiotherapy combined with adjuvant chemotherapy or induction chemotherapy has been recommended as the standard treatment for locoregionally advanced NPC in various guidelines. However, there remain shortcomings concerning current treatment modalities that should be refined in future research. In this article, we review the achievements of published clinical trials for locoregionally advanced NPC and propose future directions for subsequent clinical trials. We believe that refinement of current regimens of chemotherapy, de-intensification of treatment for specific groups of patients, developing personalized treatment based on predictors ( e.g. applying plasma Epstein–Barr virus DNA) and investigating novel therapies, such as targeted therapy and immunotherapy, should be applied with the highest priority when designing clinical trials for locoregionally advanced NPC in the next decade.

Osteoarthritis of the knee: current treatment options and future directions

2004 ◽  
Vol 18 (4) ◽  
pp. 311-320 ◽  
Author(s):  
K.G.Auw Yang ◽  
D.B.F. Saris ◽  
W.J.A. Dhert ◽  
A.J. Verbout
Keyword(s):  
Treatment Options ◽  
Current Treatment ◽  
Osteoarthritis Of The Knee ◽  
Future Directions

Meningioma: Current treatment options and future directions

2004 ◽  
Vol 5 (6) ◽  
pp. 499-509 ◽  
Author(s):  
Kevin P. McMullen ◽  
Volker W. Stieber
Keyword(s):  
Treatment Options ◽  
Current Treatment ◽  
Future Directions

An Overview of Dementias

2012 ◽  
Vol 21 (3) ◽  
pp. 75-84
Author(s):  
Venkata Vijaya K. Dalai ◽  
Jason E. Childress ◽  
Paul E Schulz
Keyword(s):  
Clinical Presentation ◽  
Treatment Options ◽  
Current Treatment ◽  
Great Variability ◽  
Health Concern ◽  
Public Health Concern ◽  
Life Threatening ◽  
The Common ◽  
Neurodegenerative Dementias ◽  
Made In

Dementia is a major public health concern that afflicts an estimated 24.3 million people worldwide. Great strides are being made in order to better diagnose, prevent, and treat these disorders. Dementia is associated with multiple complications, some of which can be life-threatening, such as dysphagia. There is great variability between dementias in terms of when dysphagia and other swallowing disorders occur. In order to prepare the reader for the other articles in this publication discussing swallowing issues in depth, the authors of this article will provide a brief overview of the prevalence, risk factors, pathogenesis, clinical presentation, diagnosis, current treatment options, and implications for eating for the common forms of neurodegenerative dementias.

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