scholarly journals Developement and application of simulation program for prediction of tissue distributions based on physiological pharmacokinetics (PPP). : Toxicokinetics of 2-chlorodibenzofuran in human body

1998 ◽  
Vol 40 (Special) ◽  
pp. 529
Author(s):  
S. Fukano
2011 ◽  
Vol 145 ◽  
pp. 384-389
Author(s):  
Seong Hyun Kim ◽  
Dong Wook Kim

With modern society entering an aging society, revitalizing elderly people's social activities and thus increasing their fall injuries leading to the fracture of various parts of the body, this study sought to examine shock amount generated when elderly people fall in diverse directions and hit the ground in a bid to develop a system aimed at minimizing shocks and preventing bone fractures. Existing studies dealt with young subjects sustaining fall injuries because a more number of elderly people suffer them, compared with young people, making it hard to obtain fall injuries data of elderly people. Thus, in this study, a system enabling a rapid movement and fall induction was used so as to simulate forced falls, and various joint movements during falls were measured using a 3-D human body movement analysis system. Young subjects participated in actual forced fall experiments, due to their safety, and their body movement data were input onto the human body movement simulation program so as to simulate falls, and resulting shock amounts were measured. Dynamic elements occurring during falls in various parts of the body, such as displacement, speed and acceleration, were input into the various parts of the body of elderly people models which were incorporated into the simulation program, and falls were simulated so as to calculate shock amounts generated when elderly people fall and hit the ground. Also, herein proposed was a system designed to reduce fall shock amounts with the aim of preventing bone fractures, using carbon dioxide gas, solenoid valves, air bag systems. This shock reduction system is believed to be used in the bone fracture prevention system that we are keeping researching on.


Author(s):  
Marek Jaśkiewicz ◽  
Damian Frej ◽  
Miloš Poliak

The article presents a model designed dummy for crash test in ADAMS. The simulated model dummy has dimensions, shapes and mass corresponding to a 50-percentile man. The simulation program allows modification of the dummy parameters. It allows to study the dynamics of motion, distribution of forces and loads of individual parts of the body of the simulated model. The article describes the design process and how to select the appropriate stiffness and damping joints for the simulated dummy. The article contains the results of simulation crash tests performed in the ADAMS program, which were compared to results of the Hybryd III dummy physical crash test. The simulation is designed to reflect the greatest compliance of the movements of individual parts of the human body during the low speed collision.


Author(s):  
Shulin Wen ◽  
Jingwei Feng ◽  
A. Krajewski ◽  
A. Ravaglioli

Hydroxyapatite bioceramics has attracted many material scientists as it is the main constituent of the bone and the teeth in human body. The synthesis of the bioceramics has been performed for years. Nowadays, the synthetic work is not only focused on the hydroapatite but also on the fluorapatite and chlorapatite bioceramics since later materials have also biological compatibility with human tissues; and they may also be very promising for clinic purpose. However, in comparison of the synthetic bioceramics with natural one on microstructure, a great differences were observed according to our previous results. We have investigated these differences further in this work since they are very important to appraise the synthetic bioceramics for their clinic application.The synthetic hydroxyapatite and chlorapatite were prepared according to A. Krajewski and A. Ravaglioli and their recent work. The briquettes from different hydroxyapatite or chlorapatite powders were fired in a laboratory furnace at the temperature of 900-1300°C. The samples of human enamel selected for the comparison with synthetic bioceramics were from Chinese adult teeth.


Author(s):  
Tong Wensheng ◽  
Lu Lianhuang ◽  
Zhang Zhijun

This is a combined study of two diffirent branches, photogrammetry and morphology of blood cells. The three dimensional quantitative analysis of erythrocytes using SEMP technique, electron computation technique and photogrammetry theory has made it possible to push the study of mophology of blood cells from LM, TEM, SEM to a higher stage, that of SEM P. A new path has been broken for deeply study of morphology of blood cells.In medical view, the abnormality of the quality and quantity of erythrocytes is one of the important changes of blood disease. It shows the abnormal blood—making function of the human body. Therefore, the study of the change of shape on erythrocytes is the indispensable and important basis of reference in the clinical diagnosis and research of blood disease.The erythrocytes of one normal person, three PNH Patients and one AA patient were used in this experiment. This research determines the following items: Height;Length of two axes (long and short), ratio; Crevice in depth and width of cell membrane; Circumference of erythrocytes; Isoline map of erythrocytes; Section map of erythrocytes.


1998 ◽  
Vol 23 (4) ◽  
pp. 382-387 ◽  
Author(s):  
James O. Ochanda ◽  
Eva A. C. Oduor ◽  
Rachel Galun ◽  
Mabel O. Imbuga ◽  
Kosta Y. Mumcuoglu

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