scholarly journals Simulation Program for Predicting the Concentration of Metabolites (A→B→C · · · ·) Formed Gradually within the Body Based on Physiological Pharmacokinetics

2001 ◽  
Vol 1 (4) ◽  
pp. 124-135
Author(s):  
Shunichi Fukano
2011 ◽  
Vol 145 ◽  
pp. 384-389
Author(s):  
Seong Hyun Kim ◽  
Dong Wook Kim

With modern society entering an aging society, revitalizing elderly people's social activities and thus increasing their fall injuries leading to the fracture of various parts of the body, this study sought to examine shock amount generated when elderly people fall in diverse directions and hit the ground in a bid to develop a system aimed at minimizing shocks and preventing bone fractures. Existing studies dealt with young subjects sustaining fall injuries because a more number of elderly people suffer them, compared with young people, making it hard to obtain fall injuries data of elderly people. Thus, in this study, a system enabling a rapid movement and fall induction was used so as to simulate forced falls, and various joint movements during falls were measured using a 3-D human body movement analysis system. Young subjects participated in actual forced fall experiments, due to their safety, and their body movement data were input onto the human body movement simulation program so as to simulate falls, and resulting shock amounts were measured. Dynamic elements occurring during falls in various parts of the body, such as displacement, speed and acceleration, were input into the various parts of the body of elderly people models which were incorporated into the simulation program, and falls were simulated so as to calculate shock amounts generated when elderly people fall and hit the ground. Also, herein proposed was a system designed to reduce fall shock amounts with the aim of preventing bone fractures, using carbon dioxide gas, solenoid valves, air bag systems. This shock reduction system is believed to be used in the bone fracture prevention system that we are keeping researching on.


Author(s):  
Mong Hien Thi Nguyen

The paper presents research to establish a simulation program on the Fuzzy logic for the Vietnamese women from 6-18 years old in Ho Chi Minh City. The author used across statistical method, component analysis method, factor analysis method, ANOVA by the SPSS software to overall test the difference between groups, and using the simulation by the Matlab software in this research. This research classified body shapes by a combination of 3 height groups, such as low, medium, and high. They combined with the FFIT and BMI standards to produce the final result of having all 27 women shapes. The results of the groups used to put into the Fuzzy logic simulation program by the Matlab software with the MISO model. It had five variables for inputs, and the output was the result of the shape which needed to know. This is scientific research, so it applies to teach subjects in the field of costume design. Besides, it supports businesses, and fashion designers will have a basis for advice on choosing costumes that fit the body shape, as well as the object of measurement, will have an objective awareness of body shapes to give training directions, adjust the physique appropriately.


Author(s):  
Marek Jaśkiewicz ◽  
Damian Frej ◽  
Miloš Poliak

The article presents a model designed dummy for crash test in ADAMS. The simulated model dummy has dimensions, shapes and mass corresponding to a 50-percentile man. The simulation program allows modification of the dummy parameters. It allows to study the dynamics of motion, distribution of forces and loads of individual parts of the body of the simulated model. The article describes the design process and how to select the appropriate stiffness and damping joints for the simulated dummy. The article contains the results of simulation crash tests performed in the ADAMS program, which were compared to results of the Hybryd III dummy physical crash test. The simulation is designed to reflect the greatest compliance of the movements of individual parts of the human body during the low speed collision.


2018 ◽  
Vol 178 ◽  
pp. 06003
Author(s):  
Camil Crăciun ◽  
Cătălin Cruceanu

Longitudinal dynamics of trains is a subject that generates discussions and views on the parameters that interfere and influence both the size of the forces and their distribution in the train body. The paper is a study to determine the influence of resistances to motion on the longitudinal dynamic forces that develop in the body of the train in the braking process. For this, a train study model of ten identical vehicles, to which the locomotive may or may not be attached, is adopted. Initially, the simulation program for the non-locomotive model is run in two variants: with and without introducing additional resistances to motion, followed by the same simulations but with the locomotive introduced and a wagon removed, thus the number of vehicles remains the same for all the cases presented.


2020 ◽  
Vol 43 ◽  
Author(s):  
David Spurrett

Abstract Comprehensive accounts of resource-rational attempts to maximise utility shouldn't ignore the demands of constructing utility representations. This can be onerous when, as in humans, there are many rewarding modalities. Another thing best not ignored is the processing demands of making functional activity out of the many degrees of freedom of a body. The target article is almost silent on both.


Author(s):  
Wiktor Djaczenko ◽  
Carmen Calenda Cimmino

The simplicity of the developing nervous system of oligochaetes makes of it an excellent model for the study of the relationships between glia and neurons. In the present communication we describe the relationships between glia and neurons in the early periods of post-embryonic development in some species of oligochaetes.Tubifex tubifex (Mull. ) and Octolasium complanatum (Dugès) specimens starting from 0. 3 mm of body length were collected from laboratory cultures divided into three groups each group fixed separately by one of the following methods: (a) 4% glutaraldehyde and 1% acrolein fixation followed by osmium tetroxide, (b) TAPO technique, (c) ruthenium red method.Our observations concern the early period of the postembryonic development of the nervous system in oligochaetes. During this period neurons occupy fixed positions in the body the only observable change being the increase in volume of their perikaryons. Perikaryons of glial cells were located at some distance from neurons. Long cytoplasmic processes of glial cells tended to approach the neurons. The superimposed contours of glial cell processes designed from electron micrographs, taken at the same magnification, typical for five successive growth stages of the nervous system of Octolasium complanatum are shown in Fig. 1. Neuron is designed symbolically to facilitate the understanding of the kinetics of the growth process.


Author(s):  
J. J. Paulin

Movement in epimastigote and trypomastigote stages of trypanosomes is accomplished by planar sinusoidal beating of the anteriorly directed flagellum and associated undulating membrane. The flagellum emerges from a bottle-shaped depression, the flagellar pocket, opening on the lateral surface of the cell. The limiting cell membrane envelopes not only the body of the trypanosome but is continuous with and insheathes the flagellar axoneme forming the undulating membrane. In some species a paraxial rod parallels the axoneme from its point of emergence at the flagellar pocket and is an integral component of the undulating membrane. A portion of the flagellum may extend beyond the anterior apex of the cell as a free flagellum; the length is variable in different species of trypanosomes.


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