Prevalence of Obesity-Related Gastrointestinal Inflammation Prior To Sleeve Gastrectomy In Adolescents

2021 ◽  
Author(s):  
Ying Z. Weatherall ◽  
Cary Cavender ◽  
Tim Jancelewicz ◽  
Emily Gray ◽  
Webb Smith ◽  
...  
Keyword(s):  
Sleeve Gastrectomy ◽  
Prevalence Of Obesity ◽  
Gastrointestinal Inflammation

Effects of Obesity Surgery on GERD and Esophageal Motility

2022 ◽  
pp. 263451612110691
Author(s):  
Anh D. Nguyen
Keyword(s):  
Bariatric Surgery ◽  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Gastric Banding ◽  
Laparoscopic Adjustable Gastric Banding ◽  
Esophageal Motility ◽  
Adjustable Gastric Banding ◽  
Esophageal Dysmotility ◽  
Obese Population ◽  
Prevalence Of Obesity

With the rising prevalence of obesity, bariatric surgery has become an increasingly popular treatment option. However, bariatric surgery can contribute to esophageal dysmotility and lead to worsening or development of GERD, two conditions that are already frequently seen in the obese population. We review the effects of the various types of bariatric surgeries on the esophagus, specifically focusing on sleeve gastrectomy, Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding.

An alternative method of surgical treatment of refractory GERD following laparoscopic sleeve gastrectomy

2019 ◽  
Vol 98 (5) ◽  
pp. 214-218
Keyword(s):  
Bariatric Surgery ◽  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Postoperative Period ◽  
Close Association ◽  
Treatment Options ◽  
Alternative Method ◽  
Refractory Gerd ◽  
Prevalence Of Obesity ◽  
The Relationship

Obesity has become a global problem with increasing prevalence. Undoubtedly, bariatric surgery is the most effective way to treat morbid obesity. Laparoscopic sleeve gastrectomy (LSG) is currently the most commonly performed bariatric procedure worldwide. The prevalence of gastroesopha- geal reflux disease (GERD) is also increasing, a close association with increasing prevalence of obesity being regarded as the main cause of this trend. The relationship between LSG and GERD is still unclear, at least controversial. If GERD occurs in the postoperative period, the first therapeutic intervention is initiation of proton pump inhibitors (PPI) treatment, which is effective in the vast majority of patients. In patients resistant to this treatment, conversion to laparoscopic Roux en Y gastric bypass (LRYGB) is usually necessary. The authors present the case report of a patient who developed GERD in the longer postoperative period and conversion to LRYGB was not appropriate due to previous complications and surgical procedures. Therefore, this patient was managed operatively by an alternative method – hiatoplasty with partial posterior fundoplication. The success of the treatment was confirmed clinically by disappearance of GERD symptomatology postoperatively even after PPI discontinuation. LRYGB is the method of choice for GERD after restrictive bariatric procedures. However, some patients are not suitable for conversion to LRYGB, and alternative treatment options are therefore needed.

scholarly journals ANALYSIS OF FOOD TOLERANCE IN PATIENTS SUBMITTED TO BARIATRIC SURGERY USING THE QUESTIONNAIRE QUALITY OF ALIMENTATION

2015 ◽  
Vol 28 (suppl 1) ◽  
pp. 79-83 ◽  
Author(s):  
Matheo Augusto Morandi STUMPF ◽  
Marcos Ricardo da Silva RODRIGUES ◽  
Ana Claudia Garabeli Cavalli KLUTHCOVSKY ◽  
Fabiana TRAVALINI ◽  
Fábio Quirillo MILLÉO
Keyword(s):  
Bariatric Surgery ◽  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Gastric Banding ◽  
Biliopancreatic Diversion ◽  
Duodenal Switch ◽  
Small Sample ◽  
Food Tolerance ◽  
Prevalence Of Obesity

Background : Due to the increased prevalence of obesity in many countries, the number of bariatric surgeries is increasing. They are considered the most effective treatment for obesity. In the postoperative there may be difficulties with the quality of alimentation, tolerance to various types of food, as well as vomiting and regurgitation. Few surveys are available to assess these difficulties in the postoperative. Aim : To perform a systematic literature review about food tolerance in patients undergoing bariatric surgery using the questionnaire "Quality of Alimentation", and compare the results between different techniques. Method : A descriptive-exploratory study where the portals Medline and Scielo were used. The following headings were used in english, spanish and portuguese: quality of alimentation, bariatric surgery and food tolerance. A total of 88 references were found, 14 used the questionnaire "Quality of Alimentation" and were selected. Results : In total, 2745 patients were interviewed of which 371 underwent to gastric banding, 1006 to sleeve gastrectomy, 1113 to Roux-en-Y gastric bypass, 14 to biliopancreatic diversion associated with duodenal switch, 83 were non-operated obese, and 158 non-obese patients. The questionnaire showed good acceptability. The biliopancreatic diversion with duodenal switch had the best food tolerance in the postoperative when compared to other techniques, but it was evaluated in a single article with a small sample. The longer the time after the operation, the better is the food tolerance. Comparing the sleeve gastrectomy and the Roux-en-Y gastric bypass, there are still controversial results in the literature. The gastric banding had the worst score of food tolerance among all the techniques evaluated. Conclusion: The questionnaire is easy and fast to assess the food tolerance in patients after bariatric surgery. Biliopancreatic diversion with duodenal switch had the best food tolerance in the postoperative when compared to sleeve gastrectomy and the Roux-en-Y gastric bypass. Gastric banding still remains in controversy, due it presented the worst score.

scholarly journals Management of Post-operative Leakage after Sleeve Gastrectomy (A Systematic Review)

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A I Khalil ◽  
M A Lasheen ◽  
I M Elzayyat ◽  
O R K Hammad
Keyword(s):  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Treatment Options ◽  
World Health ◽  
Gastric Leak ◽  
Multiple Treatment ◽  
Obesity And Overweight ◽  
Pubmed Database ◽  
Prevalence Of Obesity ◽  
Health Organization

Abstract Background the prevalence of obesity and overweight have reached epidemic proportions in the last decades, with estimates by the World Health Organization (WHO) pointing that about 2 billion people are at least overweight worldwide. Aim of the Work to establish, through the available literature, what is the current management of leakage after sleeve gastrectomy in relation to each patient’s condition through the range of interventions available and their effectiveness. Materials and Methods the search is carried out using the electronic national library of medicine’s PubMed database plus manual reference checks of articles published on laparoscopic sleeve gastrectomy for morbid obesity and its complications focusing on post-operative leakage. Electronic results were screened by title to exclude duplicate studies. Articles were identified by keywords: “laparoscopic sleeve gastrectomy” “leakage after sleeve” “gastric leak” and “management of leakage” and will be limited to research papers of all designed on human patients in English languish. Articles with no focus on leakage after sleeve gastrectomy were excluded from eligibility in this review. Results through this study, it is found that: 1- Early detection and management are very important to control the leak. 2- The early unstable patient should be operated for lavage and drainage and re-suturing of leak site if the tissue still healthy. 3- Management of the leakage after LSG still non-standardized and there are multiple treatment options, so it is important to carefully choose the best treatment options for each patient. Conclusion early diagnosis and deciding the best treatment option is important to reach a complete resolution of the leak. From this study, we concluded that treatment of gastric leak after LSG mainly depend on three factors; time of the leak, clinical presentation of the patient and site of the leak.

Adipokines as key players in β cell function and failure

2019 ◽  
Vol 133 (22) ◽  
pp. 2317-2327 ◽  
Author(s):  
Nicolás Gómez-Banoy ◽  
James C. Lo
Keyword(s):  
Metabolic Diseases ◽  
Cell Function ◽  
Whole Body ◽  
Pancreatic Β Cell ◽  
Β Cell ◽  
Cell Axis ◽  
Β Cell Function ◽  
Prevalence Of Obesity ◽  
Specific Factors ◽  
Whole Body Metabolism

Abstract The growing prevalence of obesity and its related metabolic diseases, mainly Type 2 diabetes (T2D), has increased the interest in adipose tissue (AT) and its role as a principal metabolic orchestrator. Two decades of research have now shown that ATs act as an endocrine organ, secreting soluble factors termed adipocytokines or adipokines. These adipokines play crucial roles in whole-body metabolism with different mechanisms of action largely dependent on the tissue or cell type they are acting on. The pancreatic β cell, a key regulator of glucose metabolism due to its ability to produce and secrete insulin, has been identified as a target for several adipokines. This review will focus on how adipokines affect pancreatic β cell function and their impact on pancreatic β cell survival in disease contexts such as diabetes. Initially, the “classic” adipokines will be discussed, followed by novel secreted adipocyte-specific factors that show therapeutic promise in regulating the adipose–pancreatic β cell axis.

The dual nature of obesity in metabolic programming: quantity versus quality of adipose tissue

2020 ◽  
Vol 134 (18) ◽  
pp. 2447-2451
Author(s):  
Anissa Viveiros ◽  
Gavin Y. Oudit
Keyword(s):  
Adipose Tissue ◽  
Environmental Factors ◽  
Maternal Obesity ◽  
Metabolic Programming ◽  
Dual Nature ◽  
Prevalence Of Obesity ◽  
Adipose Tissue Volume ◽  
Males And Females ◽  
Metabolically Healthy

Abstract The global prevalence of obesity has been rising at an alarming rate, accompanied by an increase in both childhood and maternal obesity. The concept of metabolic programming is highly topical, and in this context, describes a predisposition of offspring of obese mothers to the development of obesity independent of environmental factors. Research published in this issue of Clinical Science conducted by Litzenburger and colleagues (Clin. Sci. (Lond.) (2020) 134, 921–939) have identified sex-dependent differences in metabolic programming and identify putative signaling pathways involved in the differential phenotype of adipose tissue between males and females. Delineating the distinction between metabolically healthy and unhealthy obesity is a topic of emerging interest, and the precise nature of adipocytes are key to pathogenesis, independent of adipose tissue volume.

Wirkmechanismen der bariatrischen und metabolen Chirurgie

2019 ◽  
Vol 76 (3) ◽  
pp. 123-127
Author(s):  
Hanna Hosa ◽  
Marco Bueter
Keyword(s):  
Gastric Bypass ◽  
Sleeve Gastrectomy

Zusammenfassung. Zusammenfassung: Bei steigender Prävalenz der Adipositas und der damit assoziierten Komorbiditäten rückt die bariatrische und metabole Chirurgie immer mehr in den Vordergrund, wobei weltweit der Roux-Y-Magenbypass (= Roux-en-Y ­Gastric- Bypass, RYGB) und der Schlauchmagen (= Sleeve gastrectomy, SG) die häufigsten Eingriffe darstellen. Der erzielte Gewichtsverlust und das veränderte Essverhalten scheinen dabei nicht wie initial vermutet ausschliesslich auf einer ­mechanischen Restriktion der Nahrungspassage und / oder einer kalorischen Malabsorption der aufgenommenen Nahrung zu beruhen, sondern vielmehr auf ein komplexes Zusammenspiel verschiedenster physiologischer Wirkmechanismen zurückführbar zu sein. Ziel des vorliegenden Artikels ist es deshalb, vor dem Hintergrund des aktuellen Wissenstandes einen kurzen Überblick über die wichtigsten Wirkmechanismen der bariatrischen und metabolen Chirurgie zu liefern.

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