STUDIES OF NON-HEMOLYTIC HYPERBILIRUBINEMIA IN PREMATURE INFANTS

PEDIATRICS ◽  
1965 ◽  
Vol 36 (2) ◽  
pp. 162-172 ◽  
Author(s):  
Lester Wishingrad ◽  
Marvin Cornblath ◽  
Toshio Takakuwa ◽  
Irving M. Rozenfeld ◽  
Lawrence D. Elegant ◽  
...  

1. A prospective clinical study of nonhemolytic hyperbilirubinemia in premature infants included 187 infants, of whom 100 had hyperbilirubinemia above 18 mg/100 ml and 87 had bilirubin levels never in excess of 15 mg/100 ml. In a random fashion, the infants with hyperbilirubinemia were divided evenly and either received replacement transfusions or did not. 2. Of the 50 infants in the exchange transfusion group, bilirubin levels were adequately controlled in 48 infants. There was no mortality associated with the exchange transfusion procedure. After 1 year, there does not appear to be any definite evidence of kernicterus in this group. 3. In the no-exchange group, 10 of the 50 infants had levels of bilirubin over 24 mg/ 100 ml for more than 48 hours. Of these, 1 developed fatal kernicterus. Eight of the other 9 infants, whose bilirubin values exceeded 24 mg/100 ml, and 32 of the original 40, whose bilirubin levels were over 18 but below 24 mg/100 ml, were examined neurologically after 1 year. No evidence of kernicterus was found. 4. Seventy-five of the 87 control infants were also examined neurologically after 1 year and none had evidence of kernicterus. 5. The evidence to date suggests that exchange transfusions in the management of non-hemolytic hyperbilirubinemia of the premature not associated with clinical factors which may enhance the development of kernicterus such as asphyxia, hypoproteinemia, sepsis, etc., need not be performed for unconjugated bilirubin values under 24 mg/100 ml. We believe that infants who will develop bilirubin levels in excess of 24 mg/100 ml may be anticipated if their plasma values exceed 20 mg/100 ml between 73 to 96 hours of age or 22 mg/100 ml between 96 and 120 hours. 6. The validity of these conclusions is dependent upon the long-term follow-up of these infants.

Author(s):  
Lotem Goldberg ◽  
Yael Borovitz ◽  
Nir Sokolover ◽  
Asaf Lebel ◽  
Miriam Davidovits

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Rocco Borrello ◽  
Elia Bettio ◽  
Christian Bacci ◽  
Marialuisa Valente ◽  
Stefano Sivolella ◽  
...  

Peripheral Ameloblastoma (PA) is the rarest variant of ameloblastoma. It differs from the other subtypes of ameloblastoma in its localization: it arises in the soft tissues of the oral cavity coating the tooth bearing bones. Generally, it manifests nonaggressive behavior and it can be treated with complete removal by local conservative excision. In this study we report a case of PA of the maxilla in a 78-year-old female patient and we describe the four different histopathological patterns revealed by histological examination. After local excision and diagnosis, we planned a long term follow-up: in one year no recurrence had been reported. The choice of treatment is illustrated in Discussion.


1986 ◽  
Vol 65 (3) ◽  
pp. 296-302 ◽  
Author(s):  
Yoshishige Nagaseki ◽  
Tohru Shibazaki ◽  
Tatsuo Hirai ◽  
Yasuhiro Kawashima ◽  
Masafumi Hirato ◽  
...  

✓ The authors report the results of a long-term follow-up study of the effects of the physiologically defined selective VIM (nucleus ventralis intermedius)-thalamotomy on tremor of Parkinson's disease in 27 patients and essential tremor in 16 patients. The follow-up period ranged from 3.25 to 10 years (mean 6.58 years). In 43 patients a total of 50 operations (including four bilateral operations and three reoperations) were carried out. The early (2 to 4 weeks after surgery) and late effects on the tremors were determined clinically and electromyographically. Fourteen parkinsonian cases were treated with minimal lesions (about 40 cu mm). Their late results were very similar to the early results: in 10, the tremors were completely abolished, three had a slight residual tremor, and one underwent reoperation 3 months after the first surgery. Eleven essential tremor cases were treated with minimal lesions. Six of these tremors were completely abolished, four patients had slight residual tremors, and one patient with a recurrence underwent reoperation 2 years after the initial surgery. In these 23 successful operations with minimal lesions (excluding two cases with reoperation), the tremor was abolished without discernible long-lasting side effects. The other 23 operations on 16 patients with Parkinson's disease (including one reoperation) and on seven with essential tremor (one of whom also had a minimal lesion on the other side) involved relatively large lesions. In this group, the surgery was successful in almost every case. It was concluded that radiographically and physiologically monitored selective VIM-thalamotomy for parkinsonian and essential tremor is effective even when lesioning is minimal. Moreover, the beneficial effect is maintained over a long period of time.


Author(s):  
Q. Al Hinai ◽  
D. Tampieri ◽  
L. Souhami ◽  
A. Sadikot ◽  
D. Sinclair ◽  
...  

ABSTRACT:Background:Stereotactically-focused radiosurgery (SRS) for the treatment of arteriovenous malformations (AVM) has been in widespread use for over two decades. Over this timeframe the indications for treatment, standardization of radiation dosage, and the results expected from treatment have been elaborated. Less well known are the long-term complications associated with SRS. We report three patients who had SRS for the treatment of AVM who developed a cyst at the site of treatment as a late complication.Methods:From 201 patients treated by SRS for an AVM, three developed a cyst at the treatment site. Their clinical presentation, the characteristics of the AVMs and the treatment were reviewed, as well as similar cases gleaned from the literature.Results:Three women, aged 28-43 years, had an AVM treated by: craniotomy and clipping of arterial feeders followed by SRS, by craniotomy for resection followed by SRS or by endo vascular embolization and SRS. The patients did well following treatment but two of them developed a symptomatic and the other an asymptomatic cyst at the treatment site 3-19 years later. The symptomatic patients underwent marsupialization of the cyst and the other is under observation.Conclusion:Stereotactic radiosurgery is an established and safe treatment for patients with AVMs. Delayed cyst formation can occur many years after treatment and long term follow-up is indicated in patients whose AVM has been treated with SRS.


Author(s):  
Shabeer Ahmad Paul ◽  
◽  
Chandrakanta Patra ◽  
Gouranga Prasad Mondal ◽  
Ramesh Bhattacharyya ◽  
...  

Pure autonomic failure is considered to be a degenerative condition of the autonomic nervous resulting from accumulation of alpha-synuclein in autonomic ganglia [1,2]. Lack of CNS involvement distinguishes this disorder from other synucleopathies with CNS involvement like MSA, DLB and PD. However, long term follow-up of PAF patients has shown that some of these cases convert to one of these disorders most commonly MSA [3]. Also, recent data, albeit limited in nature has shown the association of REM sleep disorder in PAF patients challenging the previous notion that PAF is a disease restricted to autonomic nervous system. This data has led to the discovery of a clinical syndrome with a position in the middle of the spectrum of these disorders with PAF at one end of the spectrum and MSA, DLB and PD at the other end. We hereby present a case report of one such patient with PAF associated with RBD but without any other CNS manifestations.


2013 ◽  
Vol 9 (1-2) ◽  
pp. 51-57
Author(s):  
MS Islam ◽  
RR Kairy ◽  
M Islam ◽  
RM Manzur ◽  
NF Islam

This was a prospective clinical trial carried out at NITOR, Dhaka from July 2004 to June 2006 involving 18 patients with recurrent anterior dislocation of the shoulder. All the cases were managed by Putti-Platt operative procedure. The aim of this study was to evaluate the effectiveness of the Putti-Platt procedure in the management of recurrent anterior dislocation of the shoulder. In this study, purposing sampling methods were followed irrespective of sex. Most common age group in this series was 21-30 years. This prospective clinical study comprised with 18 patients, 16 cases (88.88%) showed excellent and good results and 2 cases (11.11%) showed fair results. Therefore, Putti-Platt procedure can be considered as an effective procedure in the treatment of recurrent anterior dislocation of shoulder. Less tissue handling, close postoperative follow-up and active muscle exercise is essential for producing good result. The long-term result is beyond the scope of this study. Long-term follow up is needed to evaluate the final out come of these patients. DOI: http://dx.doi.org/10.3329/jsf.v9i1-2.14647 J. Sci. Foundation, 9(1&2): 51-57, June-December 2011


PEDIATRICS ◽  
1962 ◽  
Vol 30 (4) ◽  
pp. 608-612
Author(s):  
Melvin Krugly ◽  
Benjamin Emanuel ◽  
William Smallberg ◽  
Secundino Veiga

A second case of a retroperitoneal xanthogranuloma in a child is presented. The tumor is very rare, and its retroperitoneal location is characteristic. The importance of this tumor is its possible relation to the other known histiocytoses, such as eosinophilic granuloma, Hand-Schüller-Christian disease, and Letterer-Siwe disease. Long-term follow-up is needed before a patient can be considered cured by surgery and x-ray therapy.


2010 ◽  
Vol 19 (9) ◽  
pp. 1459-1467 ◽  
Author(s):  
Katarina Silverplats ◽  
B. Lind ◽  
B. Zoëga ◽  
K. Halldin ◽  
M. Gellerstedt ◽  
...  

1975 ◽  
Vol 84 (6) ◽  
pp. 734-739 ◽  
Author(s):  
Roy B. Sessions ◽  
David T. Roark ◽  
Bobby R. Alford

The symptoms of Frey's syndrome are occasionally of sufficient magnitude to warrant curative treatment. In four patients, a fascia lata graft was placed under the involved skin in an attempt to offer permanent relief from the cutaneous discomfort suffered during eating. Two of these patients have excellent long-term results. The other two patients were lost to long-term follow-up but were asymptomatic several months following grafting.


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