Dysgerminoma Presenting as a Calcified Abdominal Mass With Hypercalcemia

PEDIATRICS ◽  
1978 ◽  
Vol 61 (5) ◽  
pp. 791-793
Author(s):  
Robert P. Nelken ◽  
Phillip I. Nieburg ◽  
William H. Bergstrom ◽  
Robert A. Richman

Ovarian neoplasms account for less than 2% of all pediatric malignant tumors. About one third of these tumors are pure dysgerminomas, which rarely present with abdominal calcification or hypercalcemia. This communication reports the unusual occurrence of both a calcified dysgerminoma and hypercalcemia in a 101/2-year-old girl. CASE REPORT A 101/2-year-old white girl was hospitalized for evaluation of anorexia of six months' duration, an 11-kg weight loss, polyuria, and polydipsia. On admission, she appeared weak and cachectic. Blood pressure was 110/80 mm Hg; pulse rate, 120 beats per minute; respirations, 28/mm; temperatare, 38.2 C; height, 130 cm; and weight, 25 kg. A left-lower-quadrant abdominal mass extended across the midline.

2016 ◽  
Author(s):  
Varkha Chandra ◽  
Sandhya Jain ◽  
Neerja Goel ◽  
Bindia Gupta ◽  
Shalini Rajaram

Introduction: Granulosa cell tumors comprise approximately 5% of all ovarian malignancy and account for 70% of malignant sex cord stromal tumors. Granulosa cell tumors have been diagnosed from infancy, the peak incidence being perimenopausal age. The potential of malignancy of these tumors is low, recurrences are often late and found in 10-33% of cases. Case Report: A 32-year-old P1L1 presented with large abdominal mass for which she underwent staging laparotomy with debulking surgery. She was a known case of granulosa cell tumor in the past and had undergone three laparotomies, along with chemotherapy. At the age of 13 yrs, she was diagnosed with a stage IA granulosa cell tumor (GCT) of the ovary first time. She underwent surgical staging and removal of left sided adnexal mass, after which she was asymptomatic for 7 years. In 2003 she again presented with lump abdomen for which she underwent resection of adnexal mass, histopathology was consistent with recurrent GCT. After second surgery she also received two cycles of chemotherapy. Despite adjuvant chemotherapy, patient presented again after three years in 2006 with adnexal mass and was found to have a third recurrence. At that time, she received 6 cycles of chemotherapy and the mass regressed. Meanwhile she got married and had one child. After four year in 2010 she again presented with lump abdomen and she underwent surgical staging, total abdominal hysterectomy with right salphingo ophorectomy along with removal of mass. After five year in 2015 she again presented with lump abdomen; there was a large pelvic mass which was removed and patient referred for chemotherapy. Discussion: GCTS which a rare malignant tumors of ovary tend to be associated with late recurrences. Although most recurrences occurs within 10 years after initial diagnosis, there are occasional reports of recurrences after10 years. We experienced the rare case of a patient who relapsed multiple times over 20 years, despite surgical and targeted treatment. Conclusion: The long history of granulosa cell tumor highlights the importance of extended follow up of the patient.


Medicina ◽  
2020 ◽  
Vol 56 (8) ◽  
pp. 394
Author(s):  
Ann Hee You ◽  
Jeong Eun Kim ◽  
Taewan Kwon ◽  
Tae Jun Hwang ◽  
Jeong-Hyun Choi

Background: It is recommended that a skin test be performed 4–6 weeks after anaphylaxis. However, there is little evidence about the timing of the skin test when there is a need to identify the cause within 4–6 weeks. Case report: A 57-year-old woman was scheduled to undergo surgery via a sphenoidal approach to remove a pituitary macroadenoma. Immediately after the administration of rocuronium, pulse rate increased to 120 beats/min and blood pressure dropped to 77/36 mmHg. At the same time, generalized urticaria and tongue edema were observed. Epinephrine was administered and the surgery was postponed. Reoperation was planned two weeks after the event. Four days after the anaphylactic episode, rocuronium was confirmed to be the cause by the skin prick test. Cisatracurium, which showed a negative reaction, was selected as an alternative agent for future procedures. Two weeks later, the patient underwent reoperation without any adverse events. Conclusions: The early skin test can be performed if there is a need even earlier than 4–6 weeks after anaphylaxis.


PEDIATRICS ◽  
1973 ◽  
Vol 51 (2) ◽  
pp. 289-291
Author(s):  
Manouchehr Karjoo ◽  
Harry C. Bishop ◽  
Patricia Borns ◽  
Philip G. Holtzapple

Choledochal cyst, or congenital cystic dilatation of the common bile duct, is a rare anomaly usually presenting in the first decade with pain, jaundice, and an abdominal mass. The following is a report of a child with recurrent abdominal pain who showed clinical and biochemical evidence of recurrent pancreatitis. Investigation revealed a congenital choledochal cyst. The abdominal pain and biochemical abnormalities abated after choledochocystojejunostomy. Case Report J.J., a 4-year-old white girl, was admitted to the Children's Hospital of Philadelphia because of recurrent abdominal pain. This pain, located in the epigastrium, first started at the age of 1.5 years and was associated with fever, nausea, and vomiting.


2016 ◽  
Author(s):  
Varkha Chandra ◽  
Sandhya Jain ◽  
Neerja Goel ◽  
Bindia Gupta ◽  
Shalini Rajaram

Introduction: Granulosa cell tumors comprise approximately 5% of all ovarian malignancy and account for 70% of malignant sex cord stromal tumors. Granulosa cell tumors have been diagnosed from infancy, the peak incidence being perimenopausal age. The potential of malignancy of these tumors is low, recurrences are often late and found in 10-33% of cases. Case Report: A 32-year-old P1L1 presented with large abdominal mass for which she underwent staging laparotomy with debulking surgery. She was a known case of granulosa cell tumor in the past and had undergone three laparotomies, along with chemotherapy. At the age of 13 years, she was diagnosed with a stage IA granulosa cell tumor (GCT) of the ovary first time. She underwent surgical staging and removal of left sided adnexal mass, after which she was asymptomatic for 7 years. In 2003 she again presented with lump abdomen for which she underwent resection of adnexal mass, histopathology was consistent with recurrent GCT. After second surgery she also received two cycles of chemotherapy. Despite adjuvant chemotherapy, patient presented again after three years in 2006 with adnexal mass and was found to have a third recurrence. At that time, she received 6 cycles of chemotherapy and the mass regressed. Meanwhile she got married and had one child. After four year in 2010 she again presented with lump abdomen and she underwent surgical staging, total abdominal hysterectomy with right salphingo ophorectomy along with removal of mass. After five year in 2015 she again presented with lump abdomen; there was a large pelvic mass which was removed and patient referred for chemotherapy. Discussion: GCTS which a rare malignant tumors of ovary tend to be associated with late recurrences. Although most recurrences occurs within 10 years after initial diagnosis, there are occasional reports of recurrences after10 years. We experienced the rare case of a patient who relapsed multiple times over 20 years, despite surgical and targeted treatment. In conclusion the long history of granulosa cell tumor highlights the importance of extended follow up of the patient.


Author(s):  
Sanket V. Madavi ◽  
Samruddhi Gujar ◽  
Ranjana Sharma ◽  
Ruchira Ankar ◽  
Savita Pohekar ◽  
...  

Introduction: A germ cell is a type of Tumor that arises from germ cell (GCT). Germ cell tumors are both cancerous and benign. The gonads contains majority of germ cell (ovary and testis). GCT that arise outside the gonads could be the result of embryo devlopment errors. Clinical Findings: Abdominal mass without pain, backache, and weight loss. Diagnostic Evaluation: HCG and alphafetoprotein level in the blood identifying women with malignant ovarian germ cell tumor is beneficial. Serum alphafetoprotein and HCG is elevated as condition progress. Therapeutic Intervention: Patient treated with inj. Bleomycin, inj. Cisplatin, inj.Etoposide, tab Pan 40 miligram and inj. Emset. Conclusion: A 3year old female was admitted in AVBRH Sawangi Meghe wardha with the major complaint of right abdominal swelling for 6 month, both when they observed abdominal mass without pain and swelling was small in size and backache and weight loss.


2016 ◽  
Vol 2016 ◽  
pp. 1-2 ◽  
Author(s):  
Chandra Punch ◽  
Nupur Garg ◽  
Penelope Harris

Solid pseudopapillary tumor of the pancreas (SPTP) is a rare disease of young females that does not usually recur after resection. Here we report a case of an elderly female with history of SPTP ten years ago who presented with anorexia and a palpable left lower quadrant abdominal mass. Imaging revealed metastatic disease and US-guided biopsy of the liver confirmed the diagnosis of SPTP. Due to her advanced age and comorbidities, she elected to undergo hospice care. The objective of this case report is to increase awareness of this tumor and its possibility of recurrence, necessitating further guidelines for follow-up.


2018 ◽  
Vol 5 (1) ◽  
pp. 41-50 ◽  
Author(s):  
Maria Yu. Yanitskaya ◽  
Ivan A. Turabov ◽  
Тatiana V. Turobova

Background. Treatment tactics for the intussusception (IS) in children is mainly defined the formation cause. Non operative IS treatment is most preferable. The surgery is often unreasonably performed in children over three years as the cause for IS occurrence can be a malignant tumor. Objective. Our aim was to define the features of clinical picture and diagnostics for IS associated with malignant tumors in children. Methods. We conducted the retrospective comparative assessment of reasons, registered clinical manifestations, and applied diagnostic methods in IS cases (n=373) at Arkhangelsk children's clinical hospital in 1981–2016. Two groups were analyzed: the first group (n=7) enrolled patients with IS caused by malignant tumor, the second one (n=366) — patients with IS caused by other reasons (idiopathic, mesenteric nodes hyperplasia, diverticulum, postoperative). Results. The typical combination was detected in the first group: symptoms of gastrointestinal tract (GIT) diseases and significant (8–12%) weight loss. In the first group, IS associated with tumor was observed in a few cases (1.9%), proceeded chronically (1–3 months), relapses did not occur, acute intestinal obstructions (р<0.001) were not registered; all the patients over five years were diagnosed with non-Hodgkin lymphomas if compare with the second group. The most informative diagnostic method was ultrasound imaging including hydrocolonic sonography which allowed IS diagnosing and tumor identification. In the second group, the clinical picture changed eventually: «triad» of symptoms typical for IS (abdominal colic pain, blood from rectum, abdominal mass) was registered in 1/3 of cases, significantly more often (p=0.001) the disease was demonstrated by «dyad» of symptoms (vomiting and abdominal colic pain) but always progressed to the acute form. Conclusion. The IS clinical course in children following its usual pattern significantly differs from the clinical picture associated with the tumor (though it occurs rarely, commonly in children over five years): the disease proceeds chronically with symptoms of GIT diseases and significant weight loss, relapses did not occur, no symptoms of acute intestinal obstruction are registered.


2021 ◽  
pp. 25-25
Author(s):  
Katarina Eric ◽  
Marko Miladinov ◽  
Zoran Krivokapic

INTRODUCTION: Lipomas are slow growing, benign tumors of mesenchymal origin. In most cases, they are incidental findings during endoscopic examinations. Lipomas in the gastrointestinal tract are rare entities with the lowest rate of occurrence in the rectum. They are mostly asymptomatic, but if they are larger than 4 cm can cause pain, intussusception, bleeding, volvulus, prolapse and weight loss. The aim of presented case report is to demonstrate that abundant rectorrhagia can be caused by a rare entity such as rectal lipoma. CASE REPORT: We present the case of a fifty-year-old male patient with a soft-structure prolapse through the anus accompanied by extensive bleeding. After repositioning, the structure was endoscopically removed. Histopathological analysis confirmed the presence of a lipoma. CONCLUSION: Rectorrhagia can be a clinical manifestation of this rare condition - incarcerated rectal lipoma and should be considered in practice as a differential diagnosis in cases where existence of more common conditions like hemorrhoidal disease and malignant tumors is excluded.


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