Assessment of Clinical Symptomatology and Diagnostic Features of Intestinal Intussusception associated with Malignant Tumor in Children: Results of the Retrospective Non-randomized Controlled Study

2018 ◽  
Vol 5 (1) ◽  
pp. 41-50 ◽  
Author(s):  
Maria Yu. Yanitskaya ◽  
Ivan A. Turabov ◽  
Тatiana V. Turobova
Keyword(s):  
Weight Loss ◽  
Malignant Tumor ◽  
Clinical Picture ◽  
Malignant Tumors ◽  
Abdominal Mass ◽  
Clinical Manifestations ◽  
Diagnostic Methods ◽  
Controlled Study ◽  
Tumor Identification ◽  
Abdominal Colic

Background. Treatment tactics for the intussusception (IS) in children is mainly defined the formation cause. Non operative IS treatment is most preferable. The surgery is often unreasonably performed in children over three years as the cause for IS occurrence can be a malignant tumor. Objective. Our aim was to define the features of clinical picture and diagnostics for IS associated with malignant tumors in children. Methods. We conducted the retrospective comparative assessment of reasons, registered clinical manifestations, and applied diagnostic methods in IS cases (n=373) at Arkhangelsk children's clinical hospital in 1981–2016. Two groups were analyzed: the first group (n=7) enrolled patients with IS caused by malignant tumor, the second one (n=366) — patients with IS caused by other reasons (idiopathic, mesenteric nodes hyperplasia, diverticulum, postoperative). Results. The typical combination was detected in the first group: symptoms of gastrointestinal tract (GIT) diseases and significant (8–12%) weight loss. In the first group, IS associated with tumor was observed in a few cases (1.9%), proceeded chronically (1–3 months), relapses did not occur, acute intestinal obstructions (р<0.001) were not registered; all the patients over five years were diagnosed with non-Hodgkin lymphomas if compare with the second group. The most informative diagnostic method was ultrasound imaging including hydrocolonic sonography which allowed IS diagnosing and tumor identification. In the second group, the clinical picture changed eventually: «triad» of symptoms typical for IS (abdominal colic pain, blood from rectum, abdominal mass) was registered in 1/3 of cases, significantly more often (p=0.001) the disease was demonstrated by «dyad» of symptoms (vomiting and abdominal colic pain) but always progressed to the acute form. Conclusion. The IS clinical course in children following its usual pattern significantly differs from the clinical picture associated with the tumor (though it occurs rarely, commonly in children over five years): the disease proceeds chronically with symptoms of GIT diseases and significant weight loss, relapses did not occur, no symptoms of acute intestinal obstruction are registered.

scholarly journals Clinical study on 7 cases of polypoid endometriosis. PEM: a mimic of malignancy, the symptoms of adenomyosis, endometrial polyps and infertility can assist in diagnosis

2021 ◽  
Author(s):  
Xiaohua Zheng ◽  
Ying Xu ◽  
xianjing chen ◽  
Qibing Zheng ◽  
Rong Zhao ◽  
...  
Keyword(s):  
Age Of Onset ◽  
Malignant Tumors ◽  
Clinical Manifestations ◽  
Pelvic Mass ◽  
Abnormal Uterine Bleeding ◽  
Diagnostic Methods ◽  
Pathological Examination ◽  
Rare Type ◽  
Endometrial Polyps ◽  
Polypoid Endometriosis

Abstract Objective: polypoid endometriosis (PEM) is a rare type of endometriosis (EMs), which is easy to be misdiagnosed. The purpose of this paper is to investigate the clinical features and diagnostic methods of PEM. Methods:The clinical data of 7 patients with PEM who were treated at Fujian Provincial Maternity and Children’s Hospital in China within July 2017 to December 2020 period were retrospectively analyzed, and their clinical characteristics, diagnosis, treatment and prognosis were summarized. Results: The age of onset was 31-41 (38.00 ± 1.72) years. There were 5 cases with adenomyosis, 4 cases with endometrial polyps and infertility. The clinical manifestations were diverse. Most of them were pelvic mass, compression symptoms and signs, dysmenorrhea and abnormal uterine bleeding, and three of them were similar to malignant tumors. The gross pathological features were cysts, endogenous or exogenous polypoid masses, which were all composed of endometrioid glands and stromal components, but more diverse than ordinary em. All the 7 patients were confirmed by operation and pathology. Conclusion: PEM is often complicated with adenomyosis, endometrial polyps and infertility. Pathological examination is the gold standard for diagnosis. Imaging examination is easy to be misdiagnosed. Abnormal increase of CA125 can assist in diagnosis.

scholarly journals Retroperitoneal Leiomyosarcoma with Left Hip Pain as its Clinical Manifestation: A Case Report and Literature Review

2021 ◽  
Author(s):  
Yunfu Shi ◽  
Bing Zhang ◽  
Mingxia Zhang ◽  
Wenjuan Yang ◽  
Yiming Qi ◽  
...  
Keyword(s):  
Clinical Manifestation ◽  
Malignant Tumor ◽  
Abdominal Mass ◽  
Abdominal Cavity ◽  
Clinical Manifestations ◽  
Treatment Method ◽  
Lower Limbs ◽  
Rare Type ◽  
Smooth Muscle Tissue ◽  
Psoas Major Muscle

Abstract Background: Leiomyosarcoma is a malignant tumor that originates from smooth muscle tissue, and can occur in multiple organs and tissues of the abdominal cavity, and most often in the retroperitoneum. It can occur at any age, usually 40 to 70 years old, and it is more common in women. The main clinical manifestations were abdominal discomfort, abdominal mass, abdominal pain, weight loss, nausea, vomiting or edema of the lower limbs. It is easy to invasion, recurrence and metastasis, and its prognosis is poor. Surgical resection is the preferred treatment method. Case presentation: A 55-year-old woman had pain in the left hip more than 6 years. Abdominal enhanced CT and MR showed that the tumor was located on the left side of psoas major muscle. She underwent surgical treatment, and the postoperative pathology was leiomyosarcoma. No other treatment was performed after the operation. The patient has been followed up for 78 months and no tumor recurrence. Conclusions: Retroperitoneal leiomyosarcoma is a rare type of malignant tumor with no specific clinical manifestation. Because of its atypical clinical manifestations, particular attention should be paid to avoid misdiagnosis and missed diagnosis.

Dysgerminoma Presenting as a Calcified Abdominal Mass With Hypercalcemia

PEDIATRICS ◽  
1978 ◽  
Vol 61 (5) ◽  
pp. 791-793
Author(s):  
Robert P. Nelken ◽  
Phillip I. Nieburg ◽  
William H. Bergstrom ◽  
Robert A. Richman
Keyword(s):  
Blood Pressure ◽  
Weight Loss ◽  
Case Report ◽  
Pulse Rate ◽  
Ovarian Neoplasms ◽  
Malignant Tumors ◽  
Abdominal Mass ◽  
Lower Quadrant ◽  
White Girl ◽  
Unusual Occurrence

Ovarian neoplasms account for less than 2% of all pediatric malignant tumors. About one third of these tumors are pure dysgerminomas, which rarely present with abdominal calcification or hypercalcemia. This communication reports the unusual occurrence of both a calcified dysgerminoma and hypercalcemia in a 101/2-year-old girl. CASE REPORT A 101/2-year-old white girl was hospitalized for evaluation of anorexia of six months' duration, an 11-kg weight loss, polyuria, and polydipsia. On admission, she appeared weak and cachectic. Blood pressure was 110/80 mm Hg; pulse rate, 120 beats per minute; respirations, 28/mm; temperatare, 38.2 C; height, 130 cm; and weight, 25 kg. A left-lower-quadrant abdominal mass extended across the midline.

scholarly journals Study on TCM Syndrome Differentiation of Primary Liver Cancer Based on the Analysis of Latent Structural Model

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Zhan Gu ◽  
Xiuzhong Qi ◽  
Xiaofeng Zhai ◽  
Qingbo Lang ◽  
Jianying Lu ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Structural Model ◽  
Malignant Tumors ◽  
Primary Liver Cancer ◽  
Clinical Manifestations ◽  
Active Role ◽  
Diagnostic Methods ◽  
Syndrome Differentiation ◽  
Statistical Validation ◽  
Tcm Syndrome

Primary liver cancer (PLC) is one of the most common malignant tumors because of its high incidence and high mortality. Traditional Chinese medicine (TCM) plays an active role in the treatment of PLC. As the most important part in the TCM system, syndrome differentiation based on the clinical manifestations from traditional four diagnostic methods has met great challenges and questions with the lack of statistical validation support. In this study, we provided evidences for TCM syndrome differentiation of PLC using the method of analysis of latent structural model from clinic data, thus providing basis for establishing TCM syndrome criteria. And also we obtain the common syndromes of PLC as well as their typical clinical manifestations, respectively.

scholarly journals Clinicopathological profile of ovarian tumors in the age group 10-20 years

2017 ◽  
Vol 6 (3) ◽  
pp. 877
Author(s):  
Priya V.
Keyword(s):  
Malignant Tumors ◽  
Polycystic Ovary ◽  
Abdominal Mass ◽  
Ovarian Tumors ◽  
Diagnostic Methods ◽  
Benign Tumors ◽  
Age Group ◽  
Follicular Cyst ◽  
Clinicopathological Profile ◽  
Group 10

Background: Adolescence is the period of transition from childhood to adulthood. 1% neoplasm occurs in this age group below 17 years, of this, 3% are ovarian neoplasms. Aim was to study retrospectively the clinicopathological profile and outcome of ovarian tumors in the age group 10-20 years in Government Medical College, Kottayam, Kerala, India from January 2008 for six years.Methods: Fifty Patients who have undergone laparotomy in this institution during the period were taken for study. Data regarding age, mode of presentation, diagnostic methods, treatment and histopathology were recorded. Follow-up was also taken into consideration. Patients with polycystic ovary, corpus luteal cyst, follicular cyst and endometriotic cyst are excluded.Results: Majority of the patients fall between the age group 15-20 years. Major clinical presentation was pain (40%), followed by abdominal mass. Laparotomy was done for all cases except three where laparoscopy was done. Imprint cytology taken for 3 cases. Histopathology showed malignant tumors in 6 cases and benign tumors in 44 cases. Epithelial tumors outnumbered germ cell tumors.Conclusions: This study shows the predominance of epithelial neoplasms in the age group 10-20 years. Proportion of malignancy is 12%.

scholarly journals Congenital Nasal Chondromesenchymal Hamartoma

2009 ◽  
Vol 24 (2) ◽  
pp. 23-26
Author(s):  
Ruth S. Estimar ◽  
Mario Adrian M. Zafra ◽  
Ramon Antonio B. Lopa
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Malignant Tumor ◽  
Clinical Picture ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Histopathologic Diagnosis ◽  
Design Case ◽  
One Year ◽  
Nasal Chondromesenchymal Hamartoma

Objectives: To report the case of a congenital nasal chondromesenchymal hamartoma in a one-year-old female and review the literature, identifying problems encountered in confirming the diagnosis and in treatment of this patient. Methods: Design: Case Report  Setting: Tertiary Public General Hospital Patient: One Results: A one-year-old female with an intranasal mass noted at birth and with subsequent unilateral maxillary enlargement is described. Computed tomography showed calcifications and erosion of adjacent bony structures. Histopathology and immunohistochemistry of an intranasal biopsy were interpreted as chordoma, a malignant tumor. Following surgical excision, the final histopathologic diagnosis was chondroid hamartoma. Conclusion: Only 20 cases of nasal chondromesenchymal hamartoma have been reported in the literature worldwide. These tumors may present clinically, histopathologicaly and radiologically as malignant tumors and may mislead even the experts. The whole clinical picture should be taken together to avoid misdiagnosis as a malignancy and to facilitate appropriate management.  Keywords: nasal chondromesenchymal hamartoma, nasal masses in infancy, nasal chondroid lesions

scholarly journals A Clinical Case of Stomach Perforation Concealed by a Foreign Body

2020 ◽  
Vol 10 (3) ◽  
pp. 228-232
Author(s):  
M. R. Garaev ◽  
M. Yu. Vorotnikov ◽  
Z. R. Garayeva ◽  
M. A. Nartaylakov
Keyword(s):  
Foreign Body ◽  
Clinical Picture ◽  
Clinical Case ◽  
Foreign Bodies ◽  
Abdominal Cavity ◽  
Clinical Manifestations ◽  
Diagnostic Methods ◽  
Satisfactory Condition ◽  
Therapy Choice ◽  
Ct Data

Introduction. Stomach perforations caused by ingested foreign bodies are extremely rare injuries in adults, accounting for less than 1% of all gastrointestinal perforations. The clinical picture is diverse and often presents a diagnostic problem. There are few publications reporting such cases in literature.Materials and methods. Using the example of a clinical case, this paper describes the clinical picture, diagnostic role of X-ray instruments and surgical tactics of diagnosing and treating a stomach perforation concealed by a foreign object, which occurred one week prior to admission. The patient V., 52 yo, was admitted to hospital on an emergency basis in the condition of moderate severity, complaining of abdominal pain for two days. The onset of the disease had no apparent reason. Similar pains had bothered the patient a week earlier the incident but were relieved without treatment.Results and discussion. On the basis of clinical and laboratory-instrumental data, acute pancreatitis was pre-diagnosed. Conservative drug therapy with positive dynamics was started. Two days later, computed tomography of the abdominal organs with intravenous bolus contrast was performed. According to the CT data, a foreign body in the abdominal cavity was identified, which rested on the liver at the level of the gallbladder, perforating the wall of the pyloric department of the stomach. Localized inflammatory effusion in the abdominal fat was observed. The patient was operated and discharged in satisfactory condition.Conclusion. Stomach perforations caused by small-sized foreign bodies are characterized by non-specific clinical manifestations. The use of radiation diagnostic methods facilitates the timely diagnosis and therapy choice in patients with stomach perforations caused by small-sized foreign bodies. 

scholarly journals Primary umbilical endometriosis

2018 ◽  
Vol 45 (3) ◽  
Author(s):  
PAULO VICENTE DOS SANTOS FILHO ◽  
MARCELO PROTÁSIO DOS SANTOS ◽  
SAMANTA CASTRO ◽  
VALDINALDO ARAGÃO DE MELO
Keyword(s):  
Differential Diagnosis ◽  
Clinical Picture ◽  
Clinical Manifestations ◽  
Descriptive Study ◽  
Diagnostic Methods ◽  
Menstrual Period ◽  
Histopathological Analysis ◽  
Clinical Variables ◽  
Uncommon Disease ◽  
Umbilical Endometriosis

ABSTRACT Objective: to report the characteristics, evolution and outcome of patients with primary umbilical endometriosis. Methods: an observational and descriptive study of patients with primary umbilical endometriosis diagnosed between 2014 and 2017. The clinical variables evaluated were age, clinical picture, lesion characteristics, diagnostic methods, treatment and recurrence. Results: six patients diagnosed with primary umbilical endometriosis aged 28 to 45 years were operated on during the study period. They had lesions ranging from one to 2.5cm in diameter, violet in five patients and erythematous-violaceous in one. The duration of the symptoms until diagnosis ranged from one to three years and in all the cases studied the diagnosis was made through the clinical manifestations and confirmed by histopathological analysis. No case was associated with neoplastic alterations. All patients evaluated had pain and umbilical bleeding in the menstrual period. Conclusion: umbilical endometriosis is an uncommon disease and should be included in the differential diagnosis of women as umbilical nodules. The treatment of choice is the total exeresis of the lesion.

scholarly journals Survey of the incidence, diagnosis, clinical manifestations and treatment of Spirocerca lupi in South Africa : research communication

2000 ◽  
Vol 71 (1) ◽  
Author(s):  
R.G. Lobetti
Keyword(s):  
South Africa ◽  
Weight Loss ◽  
Treatment Group ◽  
Clinical Manifestations ◽  
Clinical Findings ◽  
Diagnostic Methods ◽  
Post Mortem ◽  
Spirocerca Lupi ◽  
Seasonal Incidence ◽  
Overall Mortality

A questionnaire survey of 716 veterinary practices was undertaken to determine the incidence of Spirocerca lupi in dogs in South Africa. In total, 49 %of the questionnaires were returned, indicating a possible incidence of 28 %. Fewer than 4 cases per year were recorded by 82 %of the respondents; 4-12 by 14 %; 12-24 by 3 %; and more than 48 by only 1 %. No seasonal incidence was reported by 48 %of the respondents. Large breeds were considered to be at greater risk by 43 % of respondents. No specific age or sex was identified to be at higher risk. The most common complaints by owners and clinical findings were vomition (46 %), weight loss (27 %), coughing (21 %) or regurgitation (20 %), although 14 %of respondents reported no abnormal clinical findings. Diagnostic methods used were radiology (74 %), endoscopy (27 %), post mortem examination (34 %) and faecal flotation (4 %). Complications associated with S. lupi were reported by 76 % of respondents, which included oesophageal neoplasia (41 %), hypertrophic osteopathy (38 %) and acute haemothorax (30 %). Specific treatments were used by 58 % of the respondents, whereas 42 % of the respondents either used no treatment (72 %) or recommended euthanasia (28 %). Of the treatment group, 52 % used ivermectin, 27 % doramectin, 13 % other deworming drugs (benzimidazoles, nitroscanate), and 8 % used disophenol. Sixty-three percent of the respondents considered their treatment ineffective, whereas 31 % considered it effective, and 6 % were unsure. The overall mortality rate was high.

Estimation of the effi ciency of treatment of somatic dysfunctions of the pelvis bones using the technology of computer stabilography with biological feedback

2021 ◽  
pp. 52-65
Author(s):  
V. V. Andreev ◽  
A. I. Sychev
Keyword(s):  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Axial Skeleton ◽  
Diagnostic Methods ◽  
Controlled Study ◽  
Pubic Bone ◽  
Complete Regression ◽  
Pelvic Bones ◽  
Eyes Closed ◽  
Training Mode

Introduction. Somatic dysfunctions of the pelvic and sacral bones are one of the most common causes of lumbosacral pain with impaired spine statics, functional disorders of internal organs and other manifestations. Remote symptoms include torsional dural dysfunctions. Distortion of proprioceptive somatosensory afferentation blocks postural tonic reflexes of the axial skeleton and extremities, disrupts the sequence of activation of motor units of the locomotion system, changes the mechanisms for providing support and walking. Osteopathic correction of somatic dysfunctions in the region improves the condition of patients, however, in some cases, it is not possible to achieve complete regression of the identified syndromes. One of the effective corrective methods are computer technologies with the registration of the parameters of the static-dynamic function of support and maintaining balance. The possibilities of restoring reflex mechanisms can be obtained using computer stabilometry with a biofeedback program (BFB). Testing was carried out at the stage of diagnosis and follow-up: at the stage of screening, immediately after the treatment session, and 14 days after the moment of treatment. The clinical effect was compared with the results of stabilometric testing. The training sessions were carried out after registering the statokinesiogram.The aim of the research was to study the possibilities of using a stabiloplatform with BFB in in the mode of diagnosis of coordination and static-dynamic disorders of the axial skeleton in patients with various types of somatic dysfunctions of the pelvic bones and in the training mode together with the osteopathic correction of the somatic dysfunctions identified in patients.Materials and methods. In a prospective controlled study, the results of examination and treatment of 66 patients aged 23–56 years (median — 33) were analyzed, including 36 women and 39 men with somatic dysfunctions of the pelvic bones. In the main group, clinical and osteopathic signs of somatic dysfunctions of the pubic bone and ilium were revealed. The observation was carried out for 14 days. Osteopathic treatment of the corresponding type of dysfunction and stabilometric examination (3 control points) and training (3 sessions) were performed. Among the analyzed clinical manifestations, the intensity of pain syndrome and muscle-tonic reactions was taken into account. According to the results of the stabilometry, stability (RC) was assessed in the «eyes open» and «eyes closed» modes. The primary checkpoint is the start of observation and the correction procedure. Stage control after 7 days and the final observation point — 14 days. In total, 3–4 osteopathic sessions were carried out, stabilometric control was the screening stage, before and after the session, observation after 14 days from the last session.Results. There was detected decrease in pain intensity, normalization of axial balance and coordination of movements. The most significant was the decrease in the Romberg coefficient in patients with dysfunction of the iliac bones in the anterior rotation, regardless of the side: dynamics on the right: decrease from 570±12 to 295±23 % and on the left from 550±22 to 260±25 % (p<0,05).Conclusion. The combined use of osteopathic correction and physiotherapy exercises on a stabiloplatform in a training mode with BFB promotes regression of neurological and clinical symptoms, which is confirmed by all diagnostic methods used in the study — clinical neurological, clinical osteopathic, stabilometric with BFB. The best results were achieved in patients with somatic dysfunction anterior rotation of the ilium. The use of a stabiloplatform with BFB in the diagnostic mode allows obtaining objective data on the nature of the imbalance and balance disorders. The training regime contributes to the achievement of a therapeutic result in a short time (3 sessions) and can be used in inpatient and outpatient conditions of medical institutions.

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