The Relationship between Maternal Hypertensive Disease of Pregnancy and the Incidence of Idiopathic Respiratory Distress Syndrome

PEDIATRICS ◽  
1980 ◽  
Vol 65 (4) ◽  
pp. 735-739 ◽  
Author(s):  
Jing Ja Yoon ◽  
Schuyler Kohl ◽  
Rita G. Harper
Keyword(s):  
Mortality Rate ◽  
Respiratory Distress Syndrome ◽  
Gestational Age ◽  
Distress Syndrome ◽  
Fetal Lung ◽  
Hypertensive Disease ◽  
Lung Maturation ◽  
Idiopathic Respiratory Distress Syndrome ◽  
Fetal Lung Maturation ◽  
The Relationship

The relationship between maternal hypertensive disease of pregnancy (HDOP) and idiopathic respiratory distress syndrome (IRDS) was analyzed in 2,105 premature infants weighing between 1,000 and 2,199 gm and born between January 1968 and December 1975 at the Kings County Hospital Center and State University Hospital. HDOP was diagnosed in 250 mothers of 2,105 infants studied. The incidence of IRDS (15.2%) in the HDOP group was significantly lower than the 29.9% in the non-HDOP group (P < .001). In infants whose gestational age was 32 weeks or less, the incidence of IRDS was 26.1% in the HDOP group and 40.8% in the non-HDOP group (P < .01). In infants whose gestational age was 33 weeks or more, the incidence (9.3%) in the HDOP group was significantly lower than the 18.4% in the non-HDOP group (P < .005). The low incidence of IRDS in the HDOP group remained even after eliminating infants with known predisposing and protecting factors from the development of IRDS. The incidence of IRDS was inversely related to the severity of maternal toxemia. The total mortality and mortality with IRDS were not significantly different in both HDOP and non-HDOP groups. When the infants did not develop IRDS, the mortality rate in the HDOP group was significantly higher than that in the non-HDOP group especially in the lower gestational age group. These data suggest that chronic stress accelerates fetal lung maturation and severe chronic stress is even more effective in accelerating fetal lung maturation. When maternal toxemia was severe enough to accelerate the fetal lung maturation, the mortality rate of the infants without IRDS increased.

Neonatal Morbidity in Growth-Discordant Monochorionic Twins: Comparison Between the Larger and the Smaller Twin

2012 ◽  
Vol 15 (4) ◽  
pp. 541-546 ◽  
Author(s):  
Enrico Lopriore ◽  
Carolien Sluimers ◽  
Suzanne A. Pasman ◽  
Johanna M. Middeldorp ◽  
Dick Oepkes ◽  
...  
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Neonatal Morbidity ◽  
Fetal Lung ◽  
Cerebral Lesions ◽  
Lung Maturation ◽  
Monochorionic Twins ◽  
Increased Risk ◽  
Fetal Lung Maturation

Fetal growth restriction in singletons has been shown to enhance fetal lung maturation and reduce the risk of respiratory distress syndrome due to increased endogenous steroid production. However, data on lung maturation in growth-discordant monochorionic (thus, identical) twins are lacking. Our objective was to compare the risk of severe neonatal morbidity between the larger and the smaller twin in monochorionic twins with birth weight discordance (BWD). We included in the study all consecutive monochorionic diamniotic pregnancies with severe BWD (≥25%) and two live-born twins delivered at our center (n = 47 twin pairs). We compared the incidence of neonatal morbidity, particularly respiratory distress syndrome (RDS), and cerebral lesions between the larger and the smaller co-twin. The incidence of severe neonatal morbidity in the larger and smaller twin was 38% (18/47) and 19% (9/47), respectively (odds ratio (OR) 2.66, 95% confidence interval (CI) 0.94–7.44) and was due primarily to the higher incidence of RDS, 32% (15/47) and 6% (3/47), respectively (OR 6.88, 95% CI 1.66–32.83). In conclusion, this study shows that the larger twin in monochorionic twin pairs with BWD is at increased risk of severe neonatal morbidity, particularly RDS, compared to the smaller twin.

OBSERVATIONS ON THE RELATIONSHIP BETWEEN DURATION OF RUPTURE OF THE MEMBRANES AND THE DEVELOPMENT OF IDIOPATHIC RESPIRATORY DISTRESS SYNDROME

PEDIATRICS ◽  
1973 ◽  
Vol 52 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Jing Ja Yoon ◽  
Rita G. Harper
Keyword(s):  
Cesarean Section ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Premature Infants ◽  
Distress Syndrome ◽  
Maternal Diabetes ◽  
Fetal Asphyxia ◽  
History Of ◽  
Idiopathic Respiratory Distress Syndrome ◽  
The Relationship

Retrospective analysis of 211 premature infants between 1,001 and 2,165 gm at birth revealed a decreased incidence of idiopathic respiratory distress syndrome in infants with rupture of the membranes more than 24 hours prior to delivery. Infants with factors which are known to predispose to idiopathic respiratory distress syndrome (maternal hemorrhage, maternal diabetes, fetal asphyxia, twin B, history of a sibling with idiopathic respiratory distress syndrome and cesarean section) were then eliminated. One hundred and twenty infants remained. Infants with rupture of the membranes more than 24 hours prior to delivery had a significantly lower incidence of idiopathic respiratory distress syndrome when compared with infants with rupture of the membranes less than 12 hours prior to delivery (P<0.05). From this study it appears that rupture of the membranes for more than 24 hours prior to delivery protects against the development of idiopathic respiratory distress syndrome.

Predicting respiratory distress syndrome using gestational age and fetal lung maturity by fluorescent polarization

2005 ◽  
Vol 192 (1) ◽  
pp. 199-207 ◽  
Author(s):  
Curtis A. Parvin ◽  
Lawrence A. Kaplan ◽  
John F. Chapman ◽  
Timothy G. McManamon ◽  
Ann M. Gronowski
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Gestational Age ◽  
Distress Syndrome ◽  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Lung Maturity

scholarly journals OUTCOME OF PRETERM BABIES WITH RESPIRATORY DISTRESS SYNDROME

2021 ◽  
Vol 5 (8) ◽  
Author(s):  
Shaitan Singh Balai ◽  
Vivek Arora
Keyword(s):  
Birth Weight ◽  
Mortality Rate ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Prospective Study ◽  
Gestational Age ◽  
Distress Syndrome ◽  
Preterm Neonates ◽  
Medical College ◽  
Preterm Babies

Background: To study outcome of preterm babies with RDS in babies admitted in NICU. Methods: This study was hospital based prospective study of preterm neonates with respiratory distress syndrome admitted in NICU of MBGH RNT medical college Udaipur, from February 2017 to January 2018. Results: Among 200 preterm neonates included in the study 31 neonates expired. Mortality was 15.5%. The mortality was 10.17% among the preterm neonates with RDS and hospitalized within 6 hrs. It was 31.81% among neonates hospitalized between 6-12 hrs and 62.5% and 66.66% among neonates hospitalized between 12-24 hrs and after 24 hrs of birth respectively. Conclusion: Mortality rate is inversely related to birth weight and gestational age and directly related to age at admission and severity of respiratory distress (Silverman-Anderson score). Keywords: Preterm, Neonates, Birth weight.

Sex and Respiratory Distress Syndrome

PEDIATRICS ◽  
1982 ◽  
Vol 69 (1) ◽  
pp. 131-132
Author(s):  
Alastair A. Hutchison ◽  
Colm O'Herlihy ◽  
John H. Drew ◽  
Norman A. Beischer
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Gestational Age ◽  
Distress Syndrome ◽  
Newborn Infants ◽  
Estrogen Synthesis ◽  
Antenatal Steroid ◽  
Idiopathic Respiratory Distress Syndrome

We read with interest the recent paper by Papegeorgiou et al.1 We have studied the incidence of the idiopathic respiratory distress syndrome (IRDS) in 132 newborn infants, with gestational ages between 26 and 36 weeks, whose mothers had a urinary estriol (E3) assay during the week prior to delivery. Of the 132, 101 did not receive either antenatal steroid nor any other drug that might have interfered with estrogen synthesis. The urinary E3 excretion was defined as low (< tenth percentile for gestational age) or normal (> tenth percentile).2 The sex incidence is shown in the Table.

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