Food Allergy

PEDIATRICS ◽  
1951 ◽  
Vol 8 (1) ◽  
pp. 159-160
Keyword(s):  
Food Allergy ◽  
Dynamic Mechanism ◽  
Practical Approach ◽  
Short Period ◽  
Close Study

This, in the words of the authors, is a monograph describing the nature and dynamic mechanism of food allergy, and an outline of a practical approach to the problems inherent in its recognition and management. Food allergy is described as cyclic or fixed. A cyclic food allergy may go through the phases of masked sensitization, omission, hyperacute sensitization, active sensitization, latent sensitization and tolerance. Without a close study of their actual work it is impossible to assess this, but the authors have positively and accurately described their position in food allergy in such a manner that any debatable points can be readily proved or disproved, and undoubtedly this will be done within a short period.

scholarly journals Novel Bead-Based Epitope Assay is a sensitive and reliable tool for profiling epitope-specific antibody repertoire in food allergy

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Maria Suprun ◽  
Robert Getts ◽  
Rohit Raghunathan ◽  
Galina Grishina ◽  
Marc Witmer ◽  
...  
Keyword(s):  
Food Allergy ◽  
Specific Antibody ◽  
Allergic Sensitization ◽  
Specific Ige ◽  
Antibody Binding ◽  
Peptide Microarrays ◽  
Short Period ◽  
Reading Order ◽  
Multiple Sample ◽  
The Relationship

AbstractIdentification of allergenic IgE epitopes is instrumental for the development of novel diagnostic and prognostic methods in food allergy. In this work, we present the quantification and validation of a Bead-Based Epitope Assay (BBEA) that through multiplexing of epitopes and multiple sample processing enables completion of large experiments in a short period of time, using minimal quantities of patients’ blood. Peptides that are uniquely coupled to beads are incubated with serum or plasma samples, and after a secondary fluorophore-labeled antibody is added, the level of fluorescence is quantified with a Luminex reader. The signal is then normalized and converted to epitope-specific antibody binding values. We show that the effect of technical artifacts, i.e. well position or reading order, is minimal; and batch effects - different individual microplate runs - can be easily estimated and eliminated from the data. Epitope-specific antibody binding quantified with BBEA is highly reliable, reproducible and has greater sensitivity of epitope detection compared to peptide microarrays. IgE directed at allergenic epitopes is a sensitive biomarker of food allergy and can be used to predict allergy severity and phenotypes; and quantification of the relationship between epitope-specific IgE and IgG4 can further improve our understanding of the immune mechanisms behind allergic sensitization.

An Efficient Parking Solution: A Cam-Linkage Double-Parallelogram Mechanism Based 1-Degrees of Freedom Stack Parking System

2019 ◽  
Vol 11 (4) ◽  
Author(s):  
Chengyuan Zhang ◽  
Xiaomin Zhang ◽  
Hongyun Ye ◽  
Ming Wei ◽  
Xianxiong Ning
Keyword(s):  
Degrees Of Freedom ◽  
Digital Simulation ◽  
Residential Area ◽  
Practical Approach ◽  
Ground Vehicles ◽  
Parking Problem ◽  
Short Period ◽  
Parking System ◽  
Fillet Transition ◽  
Compact Mechanism

To solve the difficult parking problem, developing a mechanical parking device is a practical approach. Aiming at longitudinal parking, a novel compact double-stack parking system is put forward based on a 1-DOF (degree of freedom) cam-linkage double-parallelogram mechanism. Due to the unique structure, the whole device can be driven by a single motor to realize three motion periods, including lifting, translation, and fillet transition. Meanwhile, all parts of this compact mechanism can be well contained in the filleted rectangular trajectory. This rectangular trajectory is essential that we no longer need to take out the ground vehicles so as to realize stack parking. Furthermore, to overcome the singularity collinear problem of the parallelogram which may lead to the polymorphic state, the double-parallelogram mechanism is proposed to maintain the orientation of the parking platform. The digital simulation and kinetostatic analysis results demonstrate the feasibility that this novel cam-linkage double-parallelogram mechanism can improve the space utilization of the residential area, alleviate the parking problem, and can be quickly put into application on campuses or streets in a short period.

The Origin of the Moon and its Relationship to the Origin of the Solar System

1962 ◽  
Vol 14 ◽  
pp. 133-148 ◽  
Author(s):  
Harold C. Urey
Keyword(s):  
Solar System ◽  
The Moon ◽  
The Past ◽  
The Earth ◽  
Short Period ◽  
Origin Of The Moon

During the last 10 years, the writer has presented evidence indicating that the Moon was captured by the Earth and that the large collisions with its surface occurred within a surprisingly short period of time. These observations have been a continuous preoccupation during the past years and some explanation that seemed physically possible and reasonably probable has been sought.

the effects of resonance with Jupiter in the system of short-period comets

1974 ◽  
Vol 22 ◽  
pp. 193-203
Author(s):  
L̆ubor Kresák
Keyword(s):  
Structural Effects ◽  
Order Resonance ◽  
Mean Motion ◽  
Short Period ◽  
The Mean ◽  
Compound Effect ◽  
Low Order

AbstractStructural effects of the resonance with the mean motion of Jupiter on the system of short-period comets are discussed. The distribution of mean motions, determined from sets of consecutive perihelion passages of all known periodic comets, reveals a number of gaps associated with low-order resonance; most pronounced are those corresponding to the simplest commensurabilities of 5/2, 2/1, 5/3, 3/2, 1/1 and 1/2. The formation of the gaps is explained by a compound effect of five possible types of behaviour of the comets set into an approximate resonance, ranging from quick passages through the gap to temporary librations avoiding closer approaches to Jupiter. In addition to the comets of almost asteroidal appearance, librating with small amplitudes around the lower resonance ratios (Marsden, 1970b), there is an interesting group of faint diffuse comets librating in characteristic periods of about 200 years, with large amplitudes of about±8% in μ and almost±180° in σ, around the 2/1 resonance gap. This transient type of motion appears to be nearly as frequent as a circulating motion with period of revolution of less than one half that of Jupiter. The temporary members of this group are characteristic not only by their appearance but also by rather peculiar discovery conditions.

Models of comets with strongly variable nongravitational effects

1999 ◽  
Vol 173 ◽  
pp. 381-387
Author(s):  
M. Królikowska ◽  
G. Sitarski ◽  
S. Szutowicz
Keyword(s):  
Cometary Nucleus ◽  
Spin Axis ◽  
Reactive Force ◽  
Orbital Elements ◽  
Cometary Nuclei ◽  
Short Period ◽  
Basic Parameters ◽  
Polar Radius ◽  
Cometary Activity ◽  
Nongravitational Effects

AbstractThe nongravitational motion of five “erratic” short-period comets is studied on the basis of published astrometric observations. We present the precession models which successfully link all the observed apparitions of the comets: 21P/Giacobini-Zinner, 31P/Schwassmann-Wachmann 2, 32P/Comas Solá, 37P/Forbes, and 43P/Wolf-Harrington. We used the Sekanina's forced precession model of the rotating cometary nucleus to include the nongravitational terms into equations of the comet's motion. Values of six basic parameters (four connected with the rotating comet nucleus and two describing the precession of spin-axis of the nucleus) have been determined along the orbital elements from positional observations of the comets. The solutions were derived with additional assumptions which introduce instantaneous changes of modulus of reactive force,Aand of maximum of cometary activity with respect to perihelion time. The present precession models impose some contraints on sizes and rotational periods of cometary nuclei. According to our solutions the nucleus of 21P/Giacobini-Zinner with oblateness along the spin-axis of about 0.32 (equatorial to polar radius of 1.46) is the most oblate among five investigated comets.

Covering of cometary nucleus by refractory crust and its evolution into asteroid-like body

1999 ◽  
Vol 173 ◽  
pp. 365-370
Author(s):  
Kh.I. Ibadinov
Keyword(s):  
Laboratory Experiments ◽  
Cometary Nucleus ◽  
Sublimation Rate ◽  
Cometary Nuclei ◽  
Short Period Comet ◽  
Short Period ◽  
Brightness Decrease ◽  
Crust Thickness ◽  
Ice Sublimation ◽  
Period Comet

AbstractFrom the established dependence of the brightness decrease of a short-period comet dependence on the perihelion distance of its orbit it follows that part of the surface of these cometary nuclei gradually covers by a refractory crust. The results of cometary nucleus simulation show that at constant insolation energy the crust thickness is proportional to the square root of the insolation time and the ice sublimation rate is inversely proportional to the crust thickness. From laboratory experiments resulted the thermal regime, the gas productivity of the nucleus, covering of the nucleus by the crust, and the tempo of evolution of a short-period comet into the asteroid-like body studied.

From the Oort cloud to Halley-type comets

1999 ◽  
Vol 173 ◽  
pp. 327-338 ◽  
Author(s):  
J.A. Fernández ◽  
T. Gallardo
Keyword(s):  
Total Population ◽  
Complex Function ◽  
Dynamical Evolution ◽  
Oort Cloud ◽  
Capture Process ◽  
Influx Rate ◽  
Short Period ◽  
Dynamical Properties ◽  
Orbital Periods ◽  
Probability Of Capture

AbstractThe Oort cloud probably is the source of Halley-type (HT) comets and perhaps of some Jupiter-family (JF) comets. The process of capture of Oort cloud comets into HT comets by planetary perturbations and its efficiency are very important problems in comet ary dynamics. A small fraction of comets coming from the Oort cloud − of about 10−2− are found to become HT comets (orbital periods < 200 yr). The steady-state population of HT comets is a complex function of the influx rate of new comets, the probability of capture and their physical lifetimes. From the discovery rate of active HT comets, their total population can be estimated to be of a few hundreds for perihelion distancesq <2 AU. Randomly-oriented LP comets captured into short-period orbits (orbital periods < 20 yr) show dynamical properties that do not match the observed properties of JF comets, in particular the distribution of their orbital inclinations, so Oort cloud comets can be ruled out as a suitable source for most JF comets. The scope of this presentation is to review the capture process of new comets into HT and short-period orbits, including the possibility that some of them may become sungrazers during their dynamical evolution.

Sign in / Sign up

Export Citation Format

Share Document