Periventricular Echodensities Detected by Cranial Ultrasonography: Usefulness in Predicting Neurodevelopmental Outcome in Low-Birth-Weight, Preterm Infants

PEDIATRICS ◽  
1990 ◽  
Vol 85 (3) ◽  
pp. 400-404
Author(s):  
Forrest C. Bennett ◽  
Gail Silver ◽  
Edna J. Leung ◽  
Laurence A. Mack

Forty-eight low-birth-weight, preterm graduates of the University of Washington's neonatal intensive care unit who had received periodic, serial scanning by means of cranial ultrasonography during the first 4 to 6 weeks of life were longitudinally observed in an interdisciplinary neurodevelopmental follow-up program to a mean corrected age of 18 months. Mean birth weight for the sample was 1286 g; mean gestational age was 29 weeks. Periventricular echodensities were graded from 0 to 3, with 0 indicating no densities and 3 indicating cystic formation. Intracranial hemorrhage was graded in the conventional manner from 0 to IV. Neurodevelopmental outcome was assessed by means of a neurologic examination and the Bayley Scales of Infant Development. To synthesize the results, neurodevelopmental outcome for each subject was classified as normal, demonstrating minor abnormalities, or demonstrating major abnormalities. Multiple statistical analyses with various subgroupings of subjects consistently indicated severe intracranial hemorrhage (grades III and/or IV) to be a better predictor of overall neurodevelopmental outcome than grade of periventricular echodensity, including small cysts. These results suggest a wide range of outcomes after detection of periventricular echodensities and caution against communicating overly pessimistic prognoses in many cases.

PEDIATRICS ◽  
1987 ◽  
Vol 80 (1) ◽  
pp. 68-74
Author(s):  
Michael B. Resnick ◽  
Fonda Davis Eyler ◽  
Robert M. Nelson ◽  
Donald V. Eitzman ◽  
Richard L. Bucciarelli

This prospective longitudinal study was designed to evaluate the effects of a multidisciplinary infant development program (IDP) on the mental and physical development of low birth weight infants (<1,800 g). Infants in the neonatal intensive care were randomly assigned to the IDP or to traditional care (control group). IDP infants received developmental interventions in the hospital and at home through the first 2 years of life. Counseling and parenting education were provided to their parents during this same period. The control group received all the postnatal care and referrals customarily given in traditional care. Both IDP and control infants were enrolled in an independent follow-up program, which used the Bayley Scales of Infant Development in a blind evaluation design. The IDP group had a significantly lower incidence of developmental delay (P < .05) and scored significantly higher than the control group (P < .05) on mean mental and physical indices at 12 and 24 months of adjusted age.


1989 ◽  
pp. 121-122
Author(s):  
Bruce R. Boynton ◽  
Carole A. Boynton ◽  
T. Allen Merritt ◽  
Yvonne E. Vaucher ◽  
Hector E. James ◽  
...  

2013 ◽  
Vol 24 (1) ◽  
pp. 3-8
Author(s):  
N. Meena ◽  
V. K. Mohandas Kurup ◽  
S. Ramesh ◽  
R. Sathyamoorthy

Abstract A prospective, controlled trial was conducted to assess the outcome of early physical therapy intervention on preterm low birth weight infants during the first six months of life. A cohort of 100 preterm low birth weight infants who got admitted in neonatal intensive care unit (NICU) and referral newborn (RNB) of Raja Muthiah Medical College and Hospital (RMMC & H) were included prospectively. Infants who received regular early physiotherapy intervention were assigned as interventional group (EI) and infants who were advised but did not turn up for early intervention as comparison group (NEI). The Amiel-Tison neurologic examination and Denver developmental screening test (DDST) were used and results were compared. Better performance of infants was found in EI group in neurologic and developmental domains. The data suggest significant benefit of the use of EI programme over NEI in the neurodevelopmental outcome of preterm LBW infants at 6 months of corrected age.


2017 ◽  
Vol 33 (3) ◽  
pp. 524-532 ◽  
Author(s):  
Elizabeth B. Froh ◽  
Janet A. Deatrick ◽  
Martha A. Q. Curley ◽  
Diane L. Spatz

Background: Very little is known about the breastfeeding experience of mothers of infants born with congenital anomalies and cared for in the neonatal intensive care unit (NICU). Often, studies related to breastfeeding and lactation in the NICU setting are focused on the mothers of late preterm, preterm, low-birth-weight, and very-low-birth-weight infants. Congenital diaphragmatic hernia (CDH) is an anatomic malformation of the diaphragm and affects 1 in every 2,000 to 4,000 live births. Currently, there are no studies examining the health outcomes of infants with CDH and the effect of human milk. Research aim: This study aimed to describe the breastfeeding experience of mothers of infants with CDH cared for in the NICU. Methods: A prospective, longitudinal qualitative descriptive design was used. Phased interviews were conducted with a purposive sample of 11 CDH infant–mother dyads from a level 3 NICU in a children’s hospital. Results: Six themes emerged from the data: (a) hopeful for breastfeeding, (b) latching on . . . to the pump, (c) we’ve already worked so hard, (d) getting the hang of it—it’s getting easier, (e) a good safety net, and (f) finding a way that works for us. Conclusion: For this population of CDH infant–mother dyads, the term breastfeeding is not exclusive to direct feeding at the breast and the mothers emphasized the significance of providing their own mother’s milk through a combination of feeding mechanisms to their infants with CDH.


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