Chronic Fatigue Immune Dysfunction Syndrome: An Epidemic?

PEDIATRICS ◽  
1992 ◽  
Vol 89 (4) ◽  
pp. 804-804
Author(s):  
MUDR ALEŠ KMINEK ◽  
MUDR IVO SIMUNEK
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Children And Adolescents ◽  
Immune Dysfunction ◽  
Chronic Fatigue ◽  
Case Definition ◽  
Fatigue Syndrome ◽  
Definition Of ◽  
Mild Fever

To the Editor.— We read with great interest the article "Chronic Fatigue in Adolescents" by Smith et al in the August 1991 issue.1 We appreciate the statement by the authors that "the CDC-recommended criteria for case definition of the chronic fatigue syndrome (CFS) were developed mainly from adult populations and may not be appropriate for children and adolescents." We have studied children suffering from unexplained fatigue, mild fever, nonexudative pharyngitis, lymphadenopathia, etc, since 1987, ie, prior to publication of CDC-recommended criteria of CFS.2

U.S. Case Definition of Chronic Fatigue Syndrome

1999 ◽  
Vol 5 (3-4) ◽  
pp. 3-33 ◽  
Author(s):  
Leonard A. Jason ◽  
Caroline P. King ◽  
Judith A. Richman ◽  
Renee R. Taylor ◽  
Susan R. Torres ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Case Definition ◽  
Fatigue Syndrome ◽  
Definition Of

A Constructive Debate With the CDC on the Empirical Case Definition of Chronic Fatigue Syndrome

2010 ◽  
Vol 20 (4) ◽  
pp. 251-256 ◽  
Author(s):  
Leonard A. Jason ◽  
Nicole Porter ◽  
Molly Brown ◽  
Abigail Brown ◽  
Meredyth Evans
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Case Definition ◽  
Fatigue Syndrome ◽  
Definition Of

scholarly journals A Case Definition for Children with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

2008 ◽  
Vol 1 ◽  
pp. CMPed.S978 ◽  
Author(s):  
Leonard A. Jason ◽  
Nicole Porter ◽  
Elizabeth Shelleby ◽  
David S. Bell ◽  
Charles W. Lapp ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Children And Adolescents ◽  
Sensitivity And Specificity ◽  
International Association ◽  
Chronic Fatigue ◽  
Case Definition ◽  
Myalgic Encephalomyelitis ◽  
Fatigue Syndrome ◽  
Reliable Instrument

The case definition for chronic fatigue syndrome was developed for adults (Fukuda et al. 1994), and this case definition may not be appropriate for use with children and adolescents. The lack of application of a consistent pediatric definition for this illness and the lack of a reliable instrument to assess it might lead to studies which lack sensitivity and specificity. In this article, a case definition is presented that has been endorsed by the International Association of ME/CFS.

An examination of the working case definition of chronic fatigue syndrome

1996 ◽  
Vol 100 (1) ◽  
pp. 56-64 ◽  
Author(s):  
Anthony L Komaroff ◽  
Laura R Fagioli ◽  
Ann M Geiger ◽  
Teresa H Doolittle ◽  
Joshua Lee ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Case Definition ◽  
Fatigue Syndrome ◽  
Definition Of

Psychiatric adjustment in chronic fatigue syndrome of childhood and in juvenile idiopathic arthritis

2003 ◽  
Vol 33 (2) ◽  
pp. 289-297 ◽  
Author(s):  
L. RANGEL ◽  
M. E. GARRALDA ◽  
A. HALL ◽  
S. WOODHAM
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Chronic Fatigue Syndrome ◽  
Children And Adolescents ◽  
Personality Assessment ◽  
Chronic Fatigue ◽  
Self Esteem ◽  
Physical Disorder ◽  
Psychiatric Status ◽  
Fatigue Syndrome ◽  
Age Range

Background. High rates of psychopathology and of personality problems have been reported in children and adolescents with chronic fatigue syndrome (CFS). It is not clear whether this is consequent on the experience of chronic physical ill health. We compare psychiatric adjustment in children with CFS and in children suffering from another chronic physical disorder (juvenile idiopathic arthritis or JIA).Method. Our sample consisted of 28 children with CFS and 30 with JIA attending tertiary paediatric centres (age range, 11 to 18 years, mean 15, S.D. 2·3). In order to assess psychiatric status and functioning, we used the K-SADS psychiatric interviews, CGAS and Harter Self-Esteem Questionnaire with child subjects; behavioural questionnaires (CBCL) and child personality assessment interviews (PAS) with parent informants.Results. Psychiatric disorders in the year prior to interview had been present significantly more commonly in the CFS group (72% v. 34% in JIA) and were more impairing to them (CGAS scores of 45 v. 77). Most common diagnoses in both groups were depressive and anxiety disorders. Personality problems were also significantly more frequent in CFS subjects (48% disorder and 26% difficulty v. 11% and 11% in JIA). There were few differences between the two groups in self-esteem.Conclusions. Psychopathology and personality problems are common in children and adolescents with severe forms of CFS and cannot be explained strictly through the experience of chronic physical illness.

Chronic Fatigue Immune Dysfunction Syndrome: An Epidemic?

PEDIATRICS ◽  
1992 ◽  
Vol 89 (4) ◽  
pp. 802-803
Author(s):  
J. VAN AERDE
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Disease Control ◽  
Immune Dysfunction ◽  
Chronic Fatigue ◽  
Myalgic Encephalomyelitis ◽  
North American Population ◽  
American Population ◽  
The North ◽  
Fatigue Syndrome ◽  
Minor Criteria

To the Editor.— Chronic Fatigue Immune Dysfunction Syndrome (CFIDS) or Myalgic Encephalomyelitis (M.E.) is a debilitating neuroimmune disorder which is taking on epidemic proportions. Some estimates indicate that 5% of the North American population might become affected this decade. Smith et al1 confuse the symptom of "chronic fatigue" with the disease "chronic fatigue syndrome" The terminology is mixed up throughout the entire paper, but the authors clearly report on the symptom only. According to the Centers for Disease Control (CDC), the patient has to meet two major and eight minor criteria to be diagnosed with CFIDS.

Neuropsychological deficits in patients with chronic fatigue syndrome

2004 ◽  
Vol 10 (2) ◽  
pp. 278-285 ◽  
Author(s):  
KIM BUSICHIO ◽  
LANA A. TIERSKY ◽  
JOHN DELUCA ◽  
BENJAMIN H. NATELSON
Keyword(s):  
Information Processing ◽  
Chronic Fatigue Syndrome ◽  
Executive Functioning ◽  
Chronic Fatigue ◽  
Case Definition ◽  
Motor Speed ◽  
Neuropsychological Dysfunction ◽  
Speed Of Information Processing ◽  
Fatigue Syndrome ◽  
Healthy Control

The degree of neuropsychological dysfunction across multiple domains was examined in individuals suffering from chronic fatigue syndrome (CFS). In this descriptive study, a similar series of neuropsychological tests was administered to a group of CFS patients and healthy participants. More specifically, CFS patients (n = 141) who met the 1994 Case Definition criteria were compared to 76 healthy control participants on tests of memory, attention (concentration), speed of information processing, motor speed, and executive functioning. On the 18 measures administered, CFS patients scored 1 standard deviation below the healthy mean on nine measures and scored 2 standard deviations below the healthy mean on four of the measures. Moreover, results indicated that CFS patients were more likely than healthy controls to fail (1.6 SD below the healthy mean) at least one test in each of the following domains: attention, speed of information processing, and motor speed, but not on measures of memory and executive functioning. Finally, CFS patients demonstrated a greater total number of tests failed across domains. (JINS, 2004, 10, 278–285.)

scholarly journals Chronic fatigue syndrome and myalgic encephalomyelitis: towards an empirical case definition

2015 ◽  
Vol 3 (1) ◽  
pp. 82-93 ◽  
Author(s):  
Leonard A. Jason ◽  
Bobby Kot ◽  
Madison Sunnquist ◽  
Abigail Brown ◽  
Meredyth Evans ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Case Definition ◽  
Myalgic Encephalomyelitis ◽  
Fatigue Syndrome
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