scholarly journals the Irradiation of Two Cases of Gliosarcoma: Place and Modalities of Radiotherapy

2020 ◽  
Vol 8 (6) ◽  
pp. 469-473
Author(s):  
Dr. Rajae En Nouichi ◽  
Dr. Ghita Chbihi Hassani ◽  
Dr. F. Allouche ◽  
Dr. Mohamed Ait Erraisse ◽  
Dr. Z. Alami ◽  
...  
Keyword(s):  
Overall Survival ◽  
Brain Tumor ◽  
Brain Parenchyma ◽  
Optimal Treatment ◽  
Malignant Brain Tumor ◽  
Gross Total Resection ◽  
Total Resection ◽  
The Brain ◽  
Primary Malignant Brain Tumor

Introduction: Gliosarcoma is a rare histopathologic variant of glioblastoma traditionally associated with a poor prognosis.We present two cases of Gliosarcoma treated in our department. Discussion: Gliosarcoma (GSM) is a variant of glioblastoma (GBM), the most common primary malignant brain tumor that occurs in adults. GSM is characterized by its biphasic components: the gliomatous and sarcomatous components and categorized into primary and secondary GSM. Intrinsic to the brain parenchyma, GSM is usually managed by gross total resection, and radiotherapy with/without chemotherapy. Conclusion: Despite the notable advances and improvement in overall survival (OS), a consensus on the optimal treatment for GSM patients is unclear.

scholarly journals The Application of Image Segmentation to Determine the Ratio of Peritumoral Edema Area to Tumor Area on Primary Malignant Brain Tumor and Metastases through Conventional Magnetic Resonance Imaging

2022 ◽  
Vol 10 (B) ◽  
pp. 26-30
Author(s):  
Bestia Kumala Wardani ◽  
Yuyun Yueniwati ◽  
Agus Naba
Keyword(s):  
Image Segmentation ◽  
Brain Tumor ◽  
Brain Metastases ◽  
Malignant Brain Tumor ◽  
Conventional Magnetic Resonance Imaging ◽  
Peritumoral Edema ◽  
Resonance Imaging ◽  
The Brain ◽  
Primary Malignant Brain Tumor ◽  
Mri Image

BACKGROUND: Primary malignant brain tumor and metastases on the brain have a similar pattern in conventional Magnetic Resonance Imaging (MRI), even though both require entirely different treatment and management. The pathophysiological difference of peritumoral edema can help to distinguish the case of primary malignant brain tumor and brain metastases. AIM: This study aimed to analyze the ratio of the area of peritumoral edema to the tumor using Otsu’s method of image segmentation technique with a user-friendly Graphical User Interface (GUI). METODS: Data was prepared by obtaining the examination results of Anatomical Pathology and MRI imaging. The area of peritumoral edema was identified from MRI image segmentation with T2/FLAIR sequence. While the area of tumor was identified using MRI image segmentation with T1 sequence. RESULTS: The Mann-Whitney test was employed to analyze the ratio of the area of peritumoral edema to tumor on both groups. Data testing produced a significance level of 0.013 (p < 0.05) with a median value (Nmax-Nmin) of 1.14 (3.31-0.08) for the primary malignant brain tumor group and a median value (Nmax-Nmin) of 1.17 (10.30-0.90) for the brain metastases group. CONCLUSIONS: There was a significant difference in the ratio of the area of peritumoral edema to the area of tumor from both groups, in which brain metastases have a greater value than the primary malignant brain tumor.

Letter to the Editor Regarding “Association Between Facility Volume and Overall Survival for Patients with Grade II Meningioma after Gross Total Resection”

2020 ◽  
Vol 142 ◽  
pp. 537
Author(s):  
Gustavo Correa Lordelo ◽  
Victor Salviato Nespoli ◽  
Iuri Santana Neville ◽  
Wellingson Silva Paiva
Keyword(s):  
Overall Survival ◽  
Gross Total Resection ◽  
Total Resection ◽  
Letter To The Editor ◽  
Grade Ii

Young Woman With Thymoma Metastatic to the Brain Controlled With Gross Total Resection and Stereotactic Radiosurgery, With a Subsequent Uncomplicated Pregnancy

2011 ◽  
Vol 29 (2) ◽  
pp. e30-e33 ◽  
Author(s):  
Sandra S. McLaughlin ◽  
Steven J. Peckham ◽  
John A. Enis ◽  
Christopher Koebbe ◽  
Benjamin D. Smith
Keyword(s):  
Stereotactic Radiosurgery ◽  
Young Woman ◽  
Gross Total Resection ◽  
Total Resection ◽  
Uncomplicated Pregnancy ◽  
The Brain

scholarly journals Care for Dying Patients With Primary Malignant Brain Tumor

2005 ◽  
Vol 45 (12) ◽  
pp. 657-659 ◽  
Author(s):  
Kunihiko WATANABE ◽  
Rod MACLEOD
Keyword(s):  
Brain Tumor ◽  
Malignant Brain Tumor ◽  
Dying Patients ◽  
Primary Malignant Brain Tumor

scholarly journals P01.064 Correlation with MGMT pyrosequencing-based methylation levels and overall survival in glioblastoma patients with gross total resection and concomitant chemio and radiotherapy

2018 ◽  
Vol 20 (suppl_3) ◽  
pp. iii244-iii244
Author(s):  
A Parlangeli ◽  
E Pirola ◽  
M Caroli ◽  
C Pesenti ◽  
S Buonamassa ◽  
...  
Keyword(s):  
Overall Survival ◽  
Gross Total Resection ◽  
Total Resection

scholarly journals Low rates of recurrence and slow progression of pediatric pilocytic astrocytoma after gross-total resection: justification for reducing surveillance imaging

2016 ◽  
Vol 17 (5) ◽  
pp. 569-572 ◽  
Author(s):  
Andrew J. Dodgshun ◽  
Wirginia J. Maixner ◽  
Jordan R. Hansford ◽  
Michael J. Sullivan
Keyword(s):  
Overall Survival ◽  
Cost Savings ◽  
Tumor Location ◽  
Gross Total Resection ◽  
Total Resection ◽  
Routine Surveillance ◽  
Surveillance Imaging ◽  
Pilocytic Astrocytomas ◽  
Mri Scans ◽  
Mri Surveillance

OBJECTIVE Pilocytic astrocytomas (PAs) are common brain tumors in children. Optimal management of PA is gross-total resection (GTR), after which event-free survival (EFS) is excellent. The tempo of recurrences, when they do occur, is relatively sparsely reported, and there is no agreed upon surveillance recommendation for patients in this category. It has been suggested that surveillance MRI is performed too frequently and could be safely reduced in both frequency and duration. The authors conducted a retrospective review of pediatric patients with PA who underwent GTR at a single institution over an 18-year period and who had documented recurrences. METHODS All patients under 18 years of age who had undergone GTR of a PA between 1996 and 2013 were included in the study. Clinical, radiological, and tumor characteristics were recorded. RESULTS Sixty-seven patients met the criteria for GTR over the period studied. The 5-year EFS rate was 95% (95% CI 89%–100%) and overall survival was 100%. Recurrences showed a nonsignificant trend of occurring more commonly in patients with persistent nonenhancing FLAIR abnormalities after surgery, but there was no difference with regard to tumor location. All recurrences occurred before 3 years postresection, all were asymptomatic, and all patients were observed for at least one additional scan after the initial detection during routine surveillance MRI before further therapy was undertaken. CONCLUSIONS EFS and overall survival are excellent after GTR in this population with PAs. Progression after recurrence occurs slowly and is asymptomatic. A less intensive schedule of MRI surveillance in this group of patients would result in time and cost savings, without compromising safety. The authors suggest a schedule of 6 MRI scans to be obtained postoperatively, at 3–6 months, then at 1, 2, 3.5, and 5 years.

Relative survival rates and patterns of diagnosis analyzed by time period for individuals with primary malignant brain tumor, 1973–1997

2003 ◽  
Vol 99 (3) ◽  
pp. 458-466 ◽  
Author(s):  
Jill S. Barnholtz-Sloan ◽  
Andrew E. Sloan ◽  
Ann G. Schwartz
Keyword(s):  
Brain Tumor ◽  
Survival Rates ◽  
Relative Survival ◽  
Malignant Brain Tumor ◽  
Survival Times ◽  
Content Type ◽  
Study Population ◽  
Over Time ◽  
Primary Malignant Brain Tumor ◽  
Fine Print

Object. The purpose of this study was to examine patterns of diagnosis and relative survival rates in individuals in whom a primary malignant brain tumor was diagnosed between 1973 and 1997; follow-up review of these patients continued through the end of 1999. Methods. The study population was composed of 21,493 patients with primary malignant brain tumors that were diagnosed between 1973 and 1997. Data on these patients were obtained from the population-based Surveillance, Epidemiology, and End Results Program. The study population was divided into three cohorts based on the year of diagnosis, and these groups were compared with respect to variables of interest by performing chi-square tests and relative survival analysis with the life table method. Over time, there were consistently more men, more Caucasians, more patients undergoing surgery, and more individuals 70 years and older who received the diagnosis of primary malignant brain tumor. An examination of proportions of individuals with astrocytoma, other; oligodendroglioma, other; and oligodendroglioma Grade III showed significant temporal changes with frontal and temporal lobe tumors occurring most often. The diagnosis was obtained at an earlier age in African-American than in Caucasian patients. Caucasians had higher proportions of glioblastoma multiforme (GBM), which was associated with decreased survival times, and of oligodendroglioma, other, whereas African Americans had higher proportions of astrocytoma, other; ependymoma Grade II or III; and medulloblastoma, all of which were associated with increased survival times. The relative survival case demonstrated a continuous improvement over time, although older patients, those who underwent biopsy only, and those with GBMs continue to have the poorest survival times. The relative survival rates of African Americans consistently were similar or worse than those of Caucasians when the groups were stratified by prognostic factors. Conclusions. Over time, the relative survival rate of individuals with primary malignant brain tumor has improved and differences in survival are seen by examining the race of the patients.

Primary malignant brain tumor incidence and Medicaid enrollment

Neurology ◽  
2004 ◽  
Vol 63 (11) ◽  
pp. 2197-2197
Author(s):  
H. Greenberg ◽  
P. R. Sherwood
Keyword(s):  
Brain Tumor ◽  
Malignant Brain Tumor ◽  
Tumor Incidence ◽  
Medicaid Enrollment ◽  
Primary Malignant Brain Tumor

scholarly journals A New Landscape for Systemic Pharmacotherapy of Recurrent Glioblastoma?

Cancers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3775
Author(s):  
Giuseppe Lombardi ◽  
Ahmed Idbaih ◽  
Emilie Le Rhun ◽  
Matthias Preusser ◽  
Vittorina Zagonel ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Recurrent Glioblastoma ◽  
Malignant Brain Tumor ◽  
Adult Patients ◽  
Primary Malignant Brain Tumor

Glioblastoma is the most common and aggressive primary malignant brain tumor in adult patients [...]

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