Statistical Process Control for Early Detection of Progressive Cavity Pump Failures in Vertical Unconventional Gas Wells

Author(s):  
Suren Indrajith Rathnayake ◽  
Mahshid Firouzi
2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S475-S476
Author(s):  
Arthur W Baker ◽  
Ahmed Maged ◽  
Salah Haridy ◽  
Jason E Stout ◽  
Jessica L Seidelman ◽  
...  

Abstract Background Nontuberculous mycobacteria (NTM) are increasingly implicated in healthcare facility-associated (HCFA) outbreaks. However, systematic methods for NTM surveillance and outbreak detection are lacking and represent an emerging need. We examined how statistical process control (SPC) might perform in NTM outbreak detection. Methods SPC charts were optimized for surgical site infection surveillance and adapted to analyze 3 NTM outbreaks that occurred from 2013-2016 at a single hospital. The first 2 outbreaks occurred contemporaneously and consisted of pulmonary Mycobacterium abscessus complex (MABC) acquisition and cardiac surgery-associated extrapulmonary MABC infection, respectively. The third outbreak was a pseudo-outbreak of Mycobacterium avium complex (MAC) at a bronchoscopy suite. We retrospectively analyzed monthly rates of unique patients who had: 1) positive respiratory cultures for MABC obtained on hospital day 3 or later; 2) positive non-respiratory cultures for MABC; and 3) positive bronchoalveolar lavage (BAL) cultures for MAC collected at the bronchoscopy suite. For each outbreak, we used these rates to construct a standardized moving average (MA) SPC chart with MA span of 3 months. Rolling baselines were estimated from average rates for months 7 through 12 prior to each monthly data point. SPC detection was indicated by the first data point above the upper control limit (UCL) of 3 standard deviations. Traditional surveillance detection was defined as the time of outbreak detection by routine infection control procedures. Results SPC detection occurred 5, 4, and 9 months prior to traditional surveillance outbreak detection for the three outbreaks, respectively (Figures 1 and 2). Prospective NTM surveillance using the MA chart potentially would have prevented an estimated 19 cases of pulmonary MABC, 9 cases of extrapulmonary MABC, and 80 cases of BAL MAC isolation (Table). No data points exceeded the UCL during 95 cumulative months of post-outbreak surveillance, suggesting low burden of false positive SPC signals. Figure 1. Use of a moving average statistical process control (SPC) chart for early detection of hospital-associated outbreaks of pulmonary Mycobacterium abscessus complex (MABC) and cardiac surgery-associated extrapulmonary MABC infection. The pulmonary chart analyzes cases of hospital-onset respiratory isolation of MABC. The extrapulmonary chart analyzes cases of positive non-respiratory cultures for MABC. CL, center line; LCL, lower control limit; UCL, upper control limit. Figure 2. Use of a moving average statistical process control (SPC) chart for early detection of a pseudo-outbreak of Mycobacterium avium complex (MAC) that occurred at a bronchoscopy suite. The chart analyzes cases of MAC isolated from bronchoalveolar lavage cultures. CL, center line; LCL, lower control limit; UCL, upper control limit. Table. Estimated cases of hospital-associated nontuberculous mycobacteria that would have been prevented by prospective surveillance with a moving average statistical process control (SPC) chart. Conclusion A single MA SPC chart detected 3 HCFA NTM outbreaks an average of 6 months earlier than traditional surveillance. SPC has potential to improve NTM surveillance, promoting early cluster detection and prevention of HCFA NTM. Disclosures All Authors: No reported disclosures


2017 ◽  
Vol 57 (7) ◽  
pp. 1226 ◽  
Author(s):  
Momena Khatun ◽  
Cameron E. F. Clark ◽  
Nicolas A. Lyons ◽  
Peter C. Thomson ◽  
Kendra L. Kerrisk ◽  
...  

Mastitis adversely affects profit and animal welfare in the Australian dairy industry. Electrical conductivity (EC) is increasingly used to detect mastitis, but with variable results. The aim of the present study was to develop and evaluate a range of indexes and algorithms created from quarter-level EC data for the early detection of clinical mastitis at four different time windows (7 days, 14 days, 21 days, 27 days). Historical longitudinal data collected (4-week period) for 33 infected and 139 healthy quarters was used to compare the sensitivity (Se; target >80%), specificity (Sp; target >99%), accuracy (target >90%) and timing of ‘alert’ by three different approaches. These approaches involved the use of EC thresholds (range 7.5– 10 mS/cm), testing of over 250 indexes (created ad hoc), and a statistical process-control method. The indexes were developed by combining factors (and levels within each factor), such as conditional rolling average increase, percentage of variation, mean absolute deviation, mean error %; infected to non-infected ratio, all relative to the rolling average (3–9 data points) of either the affected quarter or the average of the four quarters. Using EC thresholds resulted in Se, Sp and accuracy ranging between 47% and 92%, 39% and 92% and 51% and 82% respectively (threshold 7.5 mS/cm performed best). The six highest performing indexes achieved Se, Sp and accuracy ranging between 68% and 84%, 60% and 85% and 56% and 81% respectively. The statistical process-control approach did not generate accurate predictions for early detection of clinical mastitis on the basis of EC data. Improved Sp was achieved when the time window before treatment was reduced regardless of the test approach. We concluded that EC alone cannot provide the accuracy required to detect infected quarters. Incorporating other information (e.g. milk yield, milk flow, number of incomplete milking) may increase accuracy of detection and ability to determine early onset of mastitis.


2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S4-S5
Author(s):  
Arthur W Baker ◽  
Nicole Nehls ◽  
Iulian Ilieş ◽  
James C Benneyan ◽  
Deverick J Anderson

Abstract Background We recently showed that the empirical use of a combination of 2 moving average (MA) statistical process control (SPC) charts was highly sensitive and specific for detecting potentially important increases in surgical site infection (SSI) rates. We performed this follow-up study to examine the performance of these same SPC charts when applied to known SSI outbreaks. Methods We retrospectively applied 2 MA SPC charts to all 30 SSI outbreaks investigated from 2007 to 2015 in a network of over 50 community hospitals. These outbreaks were detected via routine SSI surveillance activities that occurred in the network. We reviewed prior outbreak investigation documentation to determine the estimated time of outbreak onset and time of traditional surveillance outbreak detection. The first SPC chart utilized procedure-specific, composite SSI data from the hospital network for its baseline; the baseline for the second chart was calculated from SSI data from the outbreak hospital undergoing analysis. Both charts used rolling baseline windows but varied in baseline window size, rolling baseline lag, and MA window size. SPC chart outbreak detection occurred when either chart had a data point above the upper control limit of 1 standard deviation. Time of SPC detection was compared with both time of outbreak onset and time of traditional surveillance detection. Results With the dual chart approach, SPC detected all 30 outbreaks, including detection of 25 outbreaks (83%) prior to their estimated onset (Figure 1). SPC detection occurred a median of 16 months (interquartile range, 12–21 months) prior to the date of traditional outbreak detection, which never occurred prior to outbreak onset. Both individual SPC charts exhibited at least 90% sensitivity in outbreak detection, but the dual chart approach showed superior sensitivity and speed of detection (Figure 2). Conclusion A strategy that employed optimized, dual MA SPC charts retrospectively detected all SSI outbreaks that occurred over 9 years in a network of community hospitals. SPC outbreak detection occurred earlier than traditional surveillance detection. These optimized SPC charts merit prospective study to evaluate their ability to promote early detection of SSI clusters in real-world scenarios. Disclosures All Authors: No reported Disclosures.


Author(s):  
Mario Lesina ◽  
Lovorka Gotal Dmitrovic

The paper shows the relation among the number of small, medium and large companies in the leather and footwear industry in Croatia, as well as the relation among the number of their employees by means of the Spearman and Pearson correlation coefficient. The data were collected during 21 years. The warning zone and the risk zone were determined by means of the Statistical Process Control (SPC) for a certain number of small, medium and large companies in the leather and footwear industry in Croatia. Growth models, based on externalities, models based on research and development and the AK models were applied for the analysis of the obtained research results. The paper shows using the correlation coefficients that The relation between the number of large companies and their number of employees is the strongest, i.e. large companies have the best structured work places. The relation between the number of medium companies and the number of their employees is a bit weaker, while there is no relation in small companies. This is best described by growth models based on externalities, in which growth generates the increase in human capital, i.e. the growth of the level of knowledge and skills in the entire economy, but also deductively in companies on microeconomic level. These models also recognize the limit of accumulated knowledge after which growth may be expected. The absence of growth in small companies results from an insufficient level of human capital and failure to reach its limit level which could generate growth. According to Statistical Process Control (SPC), control charts, as well as regression models, it is clear that the most cost-effective investment is the investment into medium companies. The paper demonstrates the disadvantages in small, medium and large companies in the leather and footwear industry in Croatia. Small companies often emerge too quickly and disappear too easily owing to the employment of administrative staff instead of professional production staff. As the models emphasize, companies need to invest into their employees and employ good production staff. Investment and support to the medium companies not only strengthens the companies which have a well-arranged technological process and a good systematization of work places, but this also helps large companies, as there is a strong correlation between the number of medium and large companies.


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