A kórházi visszavételt igénylő súlyos folyadék-elektrolit zavar mint az ileosztóma egyik szövődménye

2021 ◽  
Vol 74 (2) ◽  
pp. 31-36
Author(s):  
Kornél Vajda ◽  
Ildikó Horti ◽  
Kornélia Trepák ◽  
László Sikorszki

Összefoglaló. Bevezetés: A neoadjuváns radio-kemoterápia után végzett rektum tumorok műtéte során általános gyakorlattá kezd válni a tehermentesítő ileosztóma képzése a súlyos varratelégtelenségekből származó szövődmények csökkentése érdekében. Maga az ileosztóma is 20–60%-os előfordulási gyakorisággal lehet szövődmények forrása, 16,9–40%-ban pedig a dehidráció képezi a visszavétel okát. Célkitűzés: Vizsgálatunk célja az volt, hogy áttekintsük saját beteganyagunkat az ileosztóma szövődményei alapján, különös tekintettel a dehidrációra és az abból fakadó következményekre, ennek segítségével pedig kidolgozzunk egy kezelési protokollt, amely a betegek segítségére van ezen súlyos szövődmények megelőzésében. Eredmények: Retrospektív módon elemeztük az osztályunkon 2017. 09. 01. és 2019. 12. 31. között különböző indikáció alapján készített tehermentesítő kacs ileosztóma képzésben részesült betegek morbiditási és mortalitási adatait. Ezen idő alatt 252 rektoszigmoideális reszekciót és 33 abdominoperineális rektum exstirpációt végeztünk. Ileosztómát 110 betegnél készítettünk. 27 beteg (24,5%) került visszavételre súlyos vesefunkció-romlás és ioneltérések miatt. 24 beteg egy alkalommal, 1 beteg két alkalommal, 2 beteg pedig három alkalommal került visszavételre. A visszavétel a műtéttől számítva átlagosan 49,6 nappal (1–343) történt. A felvételkor és visszavételkor a betegek átlagos GFR értéke 54,66 (38–60) ml/perc/1,73 m2 – 22,8 (5–51) ml/perc/1,73 m2 (p = 0,001), átlagos se Na 140,7 (133–145) mmol/l – 131,4 (111–144) mmol/l (p = 0,001), se K 4,6 (3,2–5,6) mmol/l – 5,37 mmol/l (3,6–7,6) (p = 0,0005) és az se Kreatinin 89,6 (54–149) µmol/l – 333,3 (107–877) (p = 0,001) µmol/l volt. Megbeszélés: Tekintettel az ileosztóma okozta dehidráció rövid és hosszú távú súlyos szövődményeire, valamint a magas visszavételi kockázatra, fontos a betegek kockázatbecslése, a korai oktatás és a dehidráció megelőzése, a rendszeres kontroll biztosítása. Amennyiben a feltételek adottak, az ileosztóma korai zárása is megfontolandó. Summary. Introduction: After the operations of rectal tumours following neoadjuvant chemo-radio therapy it is a common practice to create a defunctioning ileostomy in order to prevent complications due to anastomotic leak. The ileostomy itself can be the source of complications with 20–60% incidence rate, while dehydration causes 16.9–40% of readmissions. Aims: Our goal was to review our own cases on the basis of complications of ileostomy particularly with regard to dehydration and its consequences. We wanted to develop a therapeutic protocol to help prevent these severe complications. Results: We retrospectively analyzed the morbidity data of our patients who had defunctioning ileostomy for different indications between 01.09.2017–31.12.2019. During this period, 252 rectosigmoid resections and 33 abdominoperineal resections of the rectum were performed. Ileostomy was created for 110 patients. 27 patients (24.5%) were readmitted with severe renal impairment and electrolyte disturbances. 24 patients were readmitted once, 1 patient twice and 2 patients 3 times. Readmission happened an average of 49.6 days (1–343) after the operation. At admission and readmission the average of GFR (glomerular filtration rate) of patients was 54.66 (38–60) ml/min/1.73 m2 – 22.8 (5–51) ml/min/1.73 m2 (p = 0.001), the average of serum Na level was 140.7 (133–145) mmol/l – 131.4 (111–144) mmol/l (p = 0.001), the average of serum K level was 4.6 (3.2–5.6) mmol/l – 5.37 (3.6–7.6) mmol/l (p = 0.005) and the average of serum creatinine level was 89.6 (54–149) µmol/l – 33.3 (107–877) µmol/l (p = 0.001). Conclusion: With regard to the short and long term severe complications of dehydration and the high risk of readmission caused by ileostomy, it is important to estimate the risk of patients, to educate the inpatients as early as possible, to commence the prevention of dehydration, and regularly monitor in the outpatient setting. Provided the conditions are given, the early closure of ileostomy should be considered.

2020 ◽  
Vol 33 (Supplement_1) ◽  
Author(s):  
E Jezerskyte ◽  
H Laarhoven ◽  
M Sprangers ◽  
W Eshuis ◽  
M Hulshof ◽  
...  

Abstract   Despite the attempts to reduce postoperative complication incidence after esophageal cancer surgery, up to 60% of patients endure postoperative complications. These patients often have a reduced health related quality of life (HR-QoL) and it may also have a negative effect on long-term survival. The aim of this study is to investigate the difference in short- and long-term HR-QoL in patients with and without a complicated postoperative course. Methods A retrospective comparative cohort study was performed with data from the Dutch Cancer Registry (IKNL) and QoL questionnaires from POCOP, a longitudinal patient reported outcomes study. All patients with esophageal and gastroesophageal junction (GEJ) cancer after an esophagectomy with or without neoadjuvant chemo(radio) therapy in the period of 2015–2018 were included. Exclusion criteria were palliative surgery, patients with a recurrence, reconstruction with a colonic or jejunal interposition, no reconstruction and emergency surgery. HR-QoL was investigated at baseline and at 3, 6, 9, 12, 18 and 24 months postoperatively between patients with and without complications following an esophagectomy. Results A total of 486 patients were included: 270 with and 216 without postoperative complications. The majority of patients were male (79.8%) with a median age of 66 years (IQR 60–70.25). Significantly more patients had comorbidities in the group with postoperative complications (69.6% vs 57.3%, p = 0.001). A significant difference in HR-QoL over time was found between the two groups in “choked when swallowing” score (p = 0.028). Patients that endured postoperative complications reported more problems with choking when swallowing at 9 months follow-up (mean score 12.9 vs 8.4, p = 0.047). This difference was not clinically relevant with a mean score difference of 4.6 points. Conclusion Postoperative complications do not significantly influence the short- and long-term HR-QoL in patients following an esophagectomy. Only one HR-QoL domain showed difference over time, however, this was not clinically relevant.


2016 ◽  
Vol 33 (11) ◽  
pp. 1055-1057 ◽  
Author(s):  
Eduardo Bancalari

The patency of the ductus arteriosus is very common in extremely premature infants. The increased pulmonary blood flow that results from left-to-right ductal shunting can produce an acute deterioration in lung function and some data suggest that it may increase the risk of chronic lung damage. However, there is no clear evidence that prophylactic or early closure of the patent ductus arteriosus (PDA) results in a clear reduction in bronchopulmonary dysplasia. For this reason, and because of the side effects of the available therapies to close the ductus, there is a wide variation in the approach to the PDA in this population and most clinicians will intervene to close the ductus only in cases of significant shunt with hemodynamic decompensation.


2009 ◽  
Vol 113 (2) ◽  
pp. 185-190 ◽  
Author(s):  
Jan Persson ◽  
Petur Reynisson ◽  
Christer Borgfeldt ◽  
Paivi Kannisto ◽  
Bengt Lindahl ◽  
...  

Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Robert ◽  
Mariéthoz ◽  
Pache ◽  
Bertin ◽  
Caulfield ◽  
...  

Objective: Approximately one out of five patients with Graves' disease (GD) undergoes a thyroidectomy after a mean period of 18 months of medical treatment. This retrospective and non-randomized study from a teaching hospital compares short- and long-term results of total (TT) and subtotal thyroidectomies (ST) for this disease. Methods: From 1987 to 1997, 94 patients were operated for GD. Thirty-three patients underwent a TT (mostly since 1993) and 61 a ST (keeping 4 to 8 grams of thyroid tissue - mean 6 g). All patients had received propylthiouracil and/or neo-mercazole and were in a euthyroid state at the time of surgery; they also took potassium iodide (lugol) for ten days before surgery. Results: There were no deaths. Transient hypocalcemia (< 3 months) occurred in 32 patients (15 TT and 17 ST) and persistent hypocalcemia in 8 having had TT. Two patients developed transient recurrent laryngeal nerve palsy after ST (< 3 months). After a median follow-up period of seven years (1-15) with five patients lost to follow-up, 41 patients having had a ST are in a hypothyroid state (73%), thirteen are euthyroid (23%), and two suffered recurrent hyperthyroidism, requiring completion of thyroidectomy. All 33 patients having had TT - with follow-ups averaging two years (0.5-8) - are receiving thyroxin substitution. Conclusions: There were no instances of persistent recurrent laryngeal nerve palsy in either group, but persistent hypoparathyroidism occurred more frequently after TT. Long after ST, hypothyroidism developed in nearly three of four cases, whereas euthyroidy was maintained in only one-fourth; recurrent hyperthyroidy was rare.


Author(s):  
Ian Neath ◽  
Jean Saint-Aubin ◽  
Tamra J. Bireta ◽  
Andrew J. Gabel ◽  
Chelsea G. Hudson ◽  
...  

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