scholarly journals The use of near-infrared spectroscopy for the evaluation of a 4-week rehabilitation program in patients with COPD

2021 ◽  
Author(s):  
Botond Szucs ◽  
Mate Petrekanits ◽  
Monika Fekete ◽  
Janos T Varga
Keyword(s):  
Quality Of Life ◽  
Infrared Spectroscopy ◽  
Near Infrared ◽  
Tissue Oxygenation ◽  
Rehabilitation Program ◽  
Muscle Oxygenation ◽  
Muscle Oxygen ◽  
Total Hemoglobin ◽  
Copd Patients

Abstract Background Near-infrared spectroscopy (NIRS) technology can evaluate muscle metabolism and oxygenation. NIRS-based oximeters can measure skeletal muscle oxygen delivery and utilization during static and dynamic work non-invasively. Our goal was to assess the value and usability of NIRS technology in chronic obstructive pulmonary disease (COPD) rehabilitation program. Methods Forty patients with COPD participated in a 4-week inpatient rehabilitation program that included breathing exercises and personalized cycle/treadmill training adjusted to the functional capacity, physical activity and comorbidities of the patients. A NIRS muscle oxygen monitor was used to measure tissue oxygenation and hemoglobin levels. Total hemoglobin index, average muscle oxygenation, minimal and maximal muscle oxygenation were recorded before and after the rehabilitation program. Results Rehabilitation resulted improvement in 6 min walking distance (6MWD:335.3 ± 110. vs. 398.3 ± 126.2 m; P < 0.01), maximal inspiratory pressure (MIP: 57.7 ± 22.7 vs. 63.6 ± 18.0 cmH2O; P < 0.01), chest wall expansion (CWE: 2.84 ± 1.26 vs, 4.00 ± 1.76 cm; P < 0.01), breath hold time (BHT: 25.8 ± 10.6 vs. 29.2 ± 11.6 s; P < 0.01) and grip strength (GS: 24.9 ± 11.9 vs. 27.0 ± 11.4 kg; P < 0.01). Quality of life improvement was monitored by COPD Assessment Test (CAT: 17.00 ± 8.49 vs. 11.89 ± 7.3, P < 0.05). Total hemoglobin index (tHb: 12.8 ± 1.3% vs. 12.8 ± 1.4), average muscle oxygenation (SmO2: 67.5 ± 14.4% vs. 65.2 ± 20.4%) showed a tendency for improvement. Maximal muscle oxygenation decreased (SmO2 max: 98.0 ± 20.5% vs. 90.1 ± 14.3%; P < 0.01). Minimal muscle oxygenation increased (SmO2 min: 42.6 ± 12.6% vs. 54.8 ± 14.3%; P < 0.01). Conclusions NIRS results showed that muscle oxygenation and microcirculation can be described as a high-risk factor in COPD patients. The 4-week rehabilitation improves functional parameters, quality of life and tissue oxygenation levels in COPD patients.

Monitoring muscle oxygenation after eccentric exercise-induced muscle damage using near-infrared spectroscopy

2008 ◽  
Vol 33 (4) ◽  
pp. 743-752 ◽  
Author(s):  
Sirous Ahmadi ◽  
Peter J. Sinclair ◽  
Nasim Foroughi ◽  
Glen M. Davis
Keyword(s):  
Blood Flow ◽  
Oxygen Consumption ◽  
Infrared Spectroscopy ◽  
Oxygen Uptake ◽  
Oxygen Saturation ◽  
Eccentric Exercise ◽  
Near Infrared ◽  
Muscle Blood Flow ◽  
Muscle Oxygenation ◽  
Muscle Oxygen

Eccentric exercise (EE), a common type of muscular activity whereby muscles lengthen and contract simultaneously, is associated with higher levels of force but may also evoke muscle damage. We investigated the hypothesis that unaccustomed EE might impair muscle oxygenation and muscle blood flow in healthy adults. Ten healthy males performed a bout of 70 maximal eccentric contractions of the elbow flexors. Before and after EE on day 1 and over the next 6 days, maximum voluntary isometric torque (MVT), serum creatine kinase (CK), and the changes in muscle oxygen saturation, blood flow, and oxygen uptake (using near-infrared spectroscopy) within the biceps brachii were assessed. MVT decreased, whereas muscle soreness and CK increased after EE (p < 0.05). Mean resting oxygen saturation increased by 22% after acute EE, and remained elevated by 5%–9% for the following 6 days. During isometric contractions, significant decreases were observed in oxygen desaturation and re-saturation kinetics after EE and these declines were also significantly prevalent over the following 6 days. Both muscle blood flow and oxygen uptake increased significantly after acute EE, but recovered on the next day. This study revealed some prolonged alterations in muscle oxygenation at rest and during exercise after EE, which might be due to a decrease in muscle oxygen consumption, an increase in oxygen delivery, and (or) a combination of both. However, both oxygen consumption and blood flow recovered within 24 h after the eccentric exercise session, and therefore, the reason(s) for the changes in tissue oxygen saturation remain unknown.

Treatment of Persistent Post-Concussion Syndrome with Repetitive Transcranial Magnetic Stimulation: Using Functional Near-Infrared Spectroscopy as a Biomarker of Response (Preprint)

2021 ◽  
Author(s):  
Sané Du Plessis ◽  
Ibukunoluwa K. Oni ◽  
Andrew P. Lapointe ◽  
Christina Campbell ◽  
Jeff F. Dunn ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Infrared Spectroscopy ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Near Infrared ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Symptom Burden ◽  
Functional Near Infrared Spectroscopy ◽  
Post Concussion Syndrome

BACKGROUND Approximately one-third of all concussions lead to persistent post-concussion syndrome (PPCS). Repetitive transcranial magnetic stimulation (rTMS) is a form of non-invasive brain stimulation that has been extensively used to treat refractory major depressive disorder and has strong potential to be used as a treatment for patients with PPCS. Functional near-infrared spectroscopy (fNIRS) has already been used as a tool to assess patients with PPCS and may provide insight into the pathophysiology of rTMS treatment in patients with PPCS. OBJECTIVE The primary objective is to determine whether rTMS treatment improves symptom burden in patients with PPCS compared to sham using the Rivermead Post-concussion Symptom questionnaire as the primary outcome measure. The secondary objective is to explore the neuropathophysiological changes that occur following rTMS in patients with PPCS using fNIRS. Exploratory objectives include determining whether rTMS treatment in patients with PPCS will also improve quality of life, anxiety, depressive symptoms, cognition, post-traumatic stress and function secondary to headaches. METHODS Forty-four adults (18-65) with PPCS (>3 months-5 years) will participate in a double-blind, sham-controlled, concealed allocation, randomized clinical trial. Patients will engage in either a four-week rTMS treatment protocol or sham rTMS protocol (20 treatments). The left DLPFC will be located through Montreal Neurologic Institute (MNI) coordinates. The intensity of the rTMS will be 120% of the resting motor threshold, with a frequency of 10 Hz, 10 trains of 60 pulses/train (total of 600 pulses), and an inter-train interval of 45 seconds. Prior to starting the rTMS treatment, patient and injury characteristics, questionnaires (symptom burden, quality of life, depression, anxiety, cognition, and headache), and fNIRS assessment will be collected. Repeat questionnaires and fNIRS will occur immediately after rTMS treatment and at 1- and 3- month post-rTMS. Outcome parameters within each specific group (rTMS, sham) will be analyzed by a one-way repeated measures analysis of variance (RM-ANOVA). RESULTS To date, 5 patients have been recruited for the study and 3 have completed the rTMS protocol. The estimated completion date of the trial is April 2022. CONCLUSIONS This trial will expand our knowledge of how rTMS can be used as a treatment option of PPCS and explore the neuropathophysiological response of rTMS though fNIRS analysis. CLINICALTRIAL ClinicalTrials.gov - NCT04568369

Impact of a home-based rehabilitation program on functional respiratory parameters and quality of life in COPD patients

2021 ◽  
Author(s):  
Nidhal Belloumi ◽  
Meriem Hamdi ◽  
Imen Bachouche ◽  
Chaima Habbouria ◽  
Fatma Chermiti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rehabilitation Program ◽  
Home Based ◽  
Copd Patients ◽  
Respiratory Parameters

Potential biomarker of subjective quality of life: Prefrontal activation measurement by near-infrared spectroscopy

2013 ◽  
Vol 9 (1) ◽  
pp. 63-73 ◽  
Author(s):  
Yoshihiro Satomura ◽  
Ryu Takizawa ◽  
Shinsuke Koike ◽  
Shingo Kawasaki ◽  
Akihide Kinoshita ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Subjective Quality ◽  
Subjective Quality Of Life ◽  
Activation Measurement ◽  
Potential Biomarker

Tissue Oxygenation by Near-Infrared Spectroscopy and Muscle Blood Flow During Isometric Contractions of the Forearm

1999 ◽  
Vol 24 (3) ◽  
pp. 216-230 ◽  
Author(s):  
Andrew Hicks ◽  
Stuart Mcgill ◽  
Richard L. Hughson
Keyword(s):  
Blood Flow ◽  
Infrared Spectroscopy ◽  
Doppler Ultrasound ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Tissue Oxygenation ◽  
Muscle Blood Flow ◽  
Venous Blood ◽  
Muscle Oxygenation ◽  
Isometric Contractions

The relationship between tissue oxygenation measured by near-infrared spectroscopy (NIRS) and forearm muscle blood flow (FBF) measured by Doppler ultrasound was tested during isometric contractions at 10 and 30% maximal voluntary contraction (MVC) under conditions of normoxia and hypoxia (14% inspired O2). Six subjects maintained contractions at 10% MVCfor 5 min and at 30% for 2 min in both gas conditions. FBF was elevated during exercise at 10% MVC in hypoxia compared to normoxia, but there was no further increase in flow at 30% MVC. Median power frequency calculations from electromyographic recordings suggested progressive development of fatigue throughout both 10 and 30% MVC contractions. NIRS indicated no change in muscle oxygenation at 10% MVC, but deep venous blood O2 saturation was reduced in normoxia and more so in hypoxia. At 30% MVC, both NIRS and venous O2 saturation were reduced, with no effect of hypoxia on the NIRS signal. While NIRS might provide an indication of muscle oxygenation during isometric exercise, the conflicting findings for NIRS and direct venous blood sampling at 10 vs. 30% MVC suggest caution in the application of this noninvasive technique. Key words: exercise, Doppler ultrasound, venous blood. O2 saturation, hemoglobin

scholarly journals Effectiveness of pulmonary rehabilitation in improving quality of life in patients with different COPD stages

2020 ◽  
pp. 03-08
Author(s):  
Adrian Cosmin ILIE ◽  
Alexandru CRIŞAN ◽  
Patricia HOGEA STANCA ◽  
Daniel TRĂILĂ
Keyword(s):  
Quality Of Life ◽  
Pulmonary Rehabilitation ◽  
Rehabilitation Program ◽  
Depression Score ◽  
Stage Ii ◽  
Positive Effects ◽  
Copd Patients ◽  
The Impact ◽  
Pulmonary Rehabilitation Program

Introduction. Anxiety and depression are frequently associated conditions in COPD patients, and have also significant impact on their quality of life (QoL) and on the course of the disease. Pulmonary rehabilitation (PR) is an adjuvant, non-pharmacological method used in symptomatic COPD patients. The study aimed to evaluate the impact of COPD on QoL depending on disease severity, and to assess the supposedly positive effects of a pulmonary rehabilitation program (PRP) for COPD patients. Material and method. This research included patients with COPD GOLD stages II-IV undergoing bronchodilator therapy. QoL was assessed with the self-administered St George's Respiratory Questionnaire (SGRQ), and depression with the Beck Depression Inventory (BDI). PRP included 3-5 weekly physical training sessions for an average period of 12 weeks, but not less than 3 weeks. Results. The degree of QoL impairment was moderate in stage II (41.07) and severe in stages III (70.28) and IV (81.02). The most severe depression (score 26.6 vs 2.5 in healthy subjects) was also recorded in this group. After the patients underwent all PRP, QoL reassessment at 6 months revealed statistically significant improvements in all 3 groups (p <0.05). In the GOLD COPD stage II group the average reduction was -4.38 units, in the group GOLD COPD stage III -5.37 units, and in the GOLD COPD stage IV -6.75 units. The depression score correlated with the SGRQ score, both of them being higher in the severe stages of disease. BDI administered again 6 months after PRP revealed a significant improvement in average score in all groups, respectively a decrease of -2.17 units in the COPD II group, -2.03 units in the COPD III group and -1.88 units in group COPD IV B group. Conclusion. The results of this study demonstrate a favorable impact of PRP on improving COPD associated symptoms, depression, and QoL in all the 3 monitored COPD patient groups, with statistically significant and persistent positive results over time (6 months after completion of PRP). Key words: COPD, pulmonary rehabilitation program, Quality of life (QoL), depression,

Sign in / Sign up

Export Citation Format

Share Document