The study of the effectiveness of actography in the risk group of placental dysfunction in the third trimester of pregnancy

2017 ◽  
pp. 107-110
Author(s):  
S.I. Zhuk ◽  
◽  
V.I. Oshovskiy ◽  
Ye.G. Solovey ◽  
◽  
...  
Keyword(s):  
Fetal Growth ◽  
Growth Retardation ◽  
Risk Group ◽  
Diagnostic Methods ◽  
Controlled Study ◽  
Fetal Growth Retardation ◽  
Placental Dysfunction ◽  
Group I ◽  
Fetal Movements ◽  
Evening Peak

The objective: was to compare the frequency of diagnosis of fetal pathological conditions in the risk group of placental dysfunction (PD) in the III trimester of pregnancy. Patients and methods. In a randomized controlled study, 240 pregnant women in the III trimester of pregnancy with risk factors for PD development participated. In group I (intervention group, n=115), instruction was given on the daily actography. Patients were advised to consider fetal movements after 28 weeks of pregnancy in the evening peak of emotional activity (from 20 to 22 hours) – at least 10 movements within 2 hours. In the absence of sufficient movements, it was recommended to record CTG in the morning peak of emotional activity (7–11 H). In the 2nd (control) group (n=125), the patients received standard prenatal care. Results. The features of the course of the III trimester, childbirth and the early postpartum period were analyzed. It was revealed that the calculation of fetal movements in the evening peak of emotional activity does not affect perinatal indices, however it allows to improve detection of fetal growth retardation and does not increase the use of medical resources. Conclusion. Increasing maternal awareness of the calculation of motor activity in the fetus ensures the optimization of antenatal monitoring. The correct application of the fetal counting technique will allow the use of additional diagnostic methods in the presence of alarm signals, which, in turn, may have economic feasibility for the healthcare system. Key words: actography, fetal monitoring, placental dysfunction, fetal growth retardation.

scholarly journals FEATURES OF THE CLINICAL COURSE OF PREGNANCY, CHILDBIRTH IN WOMEN WITH COVID-19 AT DIFFERENT PERIODS OF GESTATION

2021 ◽  
pp. 39-47
Author(s):  
V. P. MISHCHENKO ◽  
I. L. GOLOVATYUK-YUZEFPOLSKAYA ◽  
I. RUDENKO ◽  
M. A. KARLYUGA ◽  
A. D. DIZIK ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Fetal Growth ◽  
Growth Retardation ◽  
Premature Birth ◽  
Clinical Course ◽  
Fetal Distress ◽  
Fetal Growth Retardation ◽  
Second Trimester ◽  
Placental Dysfunction ◽  
Threatened Abortion

The study of the features of the clinical course of pregnancy, childbirth in women who have had COVID-19 at different periods of gestation is relevant, especially in the context of a modern pandemic. Purpose of work. To determine the features of the clinical course of pregnancy, childbirth in women with COVID-19 at different periods of gestation. Materials and methods. 57 women who were ill with Covid-19 at different stages of pregnancy were examined. Results and discussion. The peculiarities of the clinical course of pregnancy, childbirth in women who have undergone Covid-19 diseases in the 1st trimesterinclude the syndrome of threatened abortion (73.6 %), placental dysfunction (100%), fetal growth retardation syndrome (42.9 %); in the second trimester - syndrome of threatened premature birth (55.6 %), placental dysfunction (100 %), amniotic fluid pathology (63.2 %); in the third trimester - anemia - in 100 %, antenatal fetal distress - in 42.1 %, pareclampsia - in 47.4 %, pathological blood loss - in 26.3 %. Conclusions. The course of pregnancy and childbirth in women who have undergone COVID-19 diseases in different trimesters of gestation have certain clinical features. Gestational complications in women who were ill in the early stages of the first trimester include the syndrome of threatened abortion, spontaneous abortion, missed abortion, premature birth in the second trimester, fetal growth retardation syndrome in the second and third trimesters. The gestational complications in women who were ill in the second trimester include the syndrome of threatened abortion, premature birth, pathology of amniotic fluid (amniotic fluid of «black» color), the phenomenon of angiitis in the abdominal cavity, placental dysfunction, fetal growth retardation syndrome, distress fetus, antenatal fetal death. The gestational complications in women who were ill in the third trimester include the syndrome of threatened premature birth, placental dysfunction, and fetal distress.

Arginine and аrginase levels in the blood serum of pregnant women with intrauterine growth retardation

2016 ◽  
pp. 97-99
Author(s):  
A.V. Basystyi ◽  
Keyword(s):  
Blood Serum ◽  
Pregnant Women ◽  
Fetal Growth ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Main Group ◽  
Control Group ◽  
Fetal Growth Retardation ◽  
Intrauterine Growth ◽  
Group I

The objective: to determine arginine and arginase levels in the blood serum of pregnant women with intrauterine growth retardation of different severity. Patients and methods. The study included 100 pregnant women (from 23 to 40 weeks of gestation). The main group consisted of 80 pregnant women with intrauterine growth retardation. The control group consisted of 20 women with physiological course of pregnancy. The patients of the main group were divided into three clinical groups regarding intrauterine growth retardation staging. Group I included 38 pregnant women with stage I IUGR, 22 pregnant women with stage II IUGR were in group II and 20 pregnant women with stage III IUGR – in group III. L-arginine concentration was determined in the blood serum by the method of T.L. Aleinikova et al [1], arginase activity – by the method of J.W. Geyer, D. Dabich [4]. The statistical analysis was performed by using standard computer programs: STATISTICA 6.0, Microsoft Excel, ANOVA. Statistically significant difference was considered at p<0.05. Results. In the study the reduced level of free arginine in the main group of pregnant women with intrauterine growth retardation of different severity was determined if compared with the control group. Fetomaternal gradient of arginine is reduced significantly due to increasing activity of the enzyme arginase, which competitively uses amino acid. Conclusions. The level of reduced free arginine in the blood serum of pregnant women with intrauterine growth retardation is directly proportional to the severity of fetal growth retardation: the more severe fetal growth retardation, the more marked arginine deficiency. For correcting metabolic disorders in pregnant women with intrauterine growth retardation it is recommended to administer L-arginine containing drugs. Key words: L-arginin, arginase, blood serum, pregnant women with intrauterine growth retardation.

scholarly journals The efficacy of prognosis and early diagnostics of fetal growth retardation

2018 ◽  
Vol 63 (6) ◽  
pp. 37-45 ◽  
Author(s):  
E. A. Degtyareva ◽  
O. A. Zakharova ◽  
M. A. Kufa ◽  
M. G. Kantemirova ◽  
V. E. Radzinskiy
Keyword(s):  
Fetal Growth ◽  
Conflict Of Interest ◽  
Growth Retardation ◽  
Financial Support ◽  
Pregnancy Complication ◽  
Diagnostic Methods ◽  
Fetal Growth Retardation ◽  
Perinatal Morbidity ◽  
Early Diagnostics ◽  
Term Infants

The fetal growth retardation takes one of  the leading places in  the structure of perinatal morbidity and mortality. The frequency of this pregnancy complication in Russia is high – from 3% to 24% among full-term infants and from 18% to 46% among premature newborns. The article analyzes the capabilities of various diagnostic methods for predicting fetal growth retardation. The more indicators are included in the review the more effective isitsreliability in the formation of risk groupsforthis pathology and more effective measures to prevent fetal growth retardation can be taken.Conflict of interest: The authors of this article confirmed the lack of conflict of interest and financial support, which should be reported.

scholarly journals MODERN DIAGNOSIS OF PLACENTAL DYSFUNCTION AND ITS COMPLICATIONS

2021 ◽  
Vol 8 (3) ◽  
pp. 182-187
Author(s):  
V.V. Lazurenko ◽  
I.B. Borzenko ◽  
O.A. Lyashchenko ◽  
O.B. Ovcharenko ◽  
D.Yu. Tertyshnyk
Keyword(s):  
Pregnant Women ◽  
Fetal Growth ◽  
Growth Retardation ◽  
Main Group ◽  
Control Group ◽  
Prospective Clinical Study ◽  
Fetal Growth Retardation ◽  
Clinical Algorithm ◽  
Vascular Growth ◽  
Placental Dysfunction

The aim of the study was to improve the modern diagnosis of placental dysfunction and its complications. Materials and methods. The study involved a prospective survey of 70 pregnant women divided into the main group (pregnant women with placental dysfunction) (n = 50) and the control group (n = 20). The main group was divided into subgroups of pregnant women with placental dysfunction and fetal growth retardation (n = 30) and pregnant women with placental dysfunction without fetal growth retardation (n = 20). The control group comprised 20 pregnant women with physiological gestation. Apart from history taking, the study comprised obstetric and general clinical examination, evaluation of endothelium- dependent vasodilation, serum concentrations of soluble forms of vascular and platelet- endothelial molecules of cell adhesion 1, indicators of athrombogenicity of the vascular growth wall, uterine-placental-fetal blood circulation, pathomorphological and histometric examination of the placenta. Results. Based on the obtained clinical-morphological and endotheliotropic criteria, a personalized clinical algorithm for managing pregnant women with placental dysfunction was developed and implemented. Conclusions. Assessment of pregnancy results in a prospective clinical study showed that the proposed algorithm for personalization of the risk of perinatal abnormalities not only helped to avoid antenatal mortality, but also to prevent intranatal and early neonatal losses in patients with placental dysfunction and fetal growth retardation.

A Prospective Study of Haemostatic Tests at 28 Weeks Gestation as Predictors of Pre-Eclampsia and Growth Retardation

1989 ◽  
Vol 61 (02) ◽  
pp. 243-245 ◽  
Author(s):  
J G Thornton ◽  
B J Molloy ◽  
P S Vinall ◽  
P R Philips ◽  
R Hughes ◽  
...  
Keyword(s):  
Discriminant Analysis ◽  
Prospective Study ◽  
Fetal Growth ◽  
Growth Retardation ◽  
Degradation Products ◽  
Fetal Growth Retardation ◽  
Fibrin Degradation Products ◽  
A Prospective Study ◽  
Primiparous Women ◽  
Significant Model

SummaryA panel of haemostatic tests was perfomed on 400 primiparous women at 28 weeks to test whether one or more could predict the development of pregnancy complications. Fifteen women subsequently developed pre-eclampsia with significant proteinuria and 13 delivered growth retarded infants. There were no significant differences between mothers in the pre-eclampsia group and 22 randomly selected controls. A stepwise logistic discriminant analysis of the data did not produce a significant model. In the growth retarded group only beta thromboglobulin levels were significantly lower than in the controls (p <0.05), although in the logistic discriminant analysis the inclusion of both beta thromboglobulin and fibrin degradation products led to a borderline significant improvement in fit of the model. We conclude that the haemostatic variables studied are not significantly changed at 28 weeks nor clinically useful predictors of either pre-eclampsia or fetal growth retardation.

Uteroplacental hemodynamic disturbances in establishment of fetal growth retardation in streptozocin-induced diabetic rats

Diabetes ◽  
1990 ◽  
Vol 39 (6) ◽  
pp. 743-746 ◽  
Author(s):  
N. C. Chartrel ◽  
M. T. Clabaut ◽  
F. A. Boismare ◽  
J. C. Schrub
Keyword(s):  
Fetal Growth ◽  
Growth Retardation ◽  
Diabetic Rats ◽  
Fetal Growth Retardation

VITAMIN D DEFICIENCY AND SYNDROME FETAL GROWTH RETARDATION

2020 ◽  
Vol 22 (3) ◽  
pp. 13-17
Author(s):  
Bushueva E.V. ◽  
◽  
Levitskaya V.M. ◽  
Boboeva Sh.G. ◽  
Sidorova T.N. ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Fetal Growth ◽  
Growth Retardation ◽  
Fetal Growth Retardation
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