Vertical ridge augmentation with a honeycomb structure titanium membrane: A technical note for three-dimensional curvature bending method

2020 ◽  
Author(s):  
Tomohiro Ishikawa ◽  
Daisuke Ueno
Keyword(s):  
Bone Regeneration ◽  
Animal Studies ◽  
Fibrous Tissue ◽  
Three Dimensional ◽  
External Pressure ◽  
Honeycomb Structure ◽  
Technical Note ◽  
Ridge Augmentation ◽  
Bending Process ◽  
Titanium Membrane

Guided bone regeneration (GBR) is the most commonly used technique for vertical ridge augmentation (VRA), and is popular because it is less invasive and highly formative. Since the augmented site is exposed to external pressure, it is preferable to support the membrane by a framework in order to maintain the shape of the VRA. Recently, a titanium framework reinforced ultrafine titanium membrane was developed by laser processing technology. The technique allows microperforations to be made (φ20 μm) into a titanium membrane, which is expected to prevent fibrous tissue ingrowth from outside the membrane. In addition, significant bone regeneration has been confirmed on ridge defects in previous animal studies. However, the membrane tends to crumple during the bending process because it is very thin (20 μm), so the bending procedures are technically sensitive. Since this titanium honeycomb membrane was first approved for clinical use in Japan, no international clinical reports have been published. The purpose of this case report is to describe a technical note for a three- dimensional curvature bending method in VRA using the newly developed honeycomb structure Ti-membrane.

scholarly journals Combined use of xenogenous bone blocks and guided bone regeneration for three-dimensional augmentation of anterior maxillary ridge: A case series

2019 ◽  
Vol 11 (2) ◽  
pp. 94-98
Author(s):  
Mohammadreza Talebi ◽  
Noushin Janbakhsh
Keyword(s):  
Bone Regeneration ◽  
Primary Closure ◽  
Three Dimensional ◽  
Case Series ◽  
Guided Bone Regeneration ◽  
Alveolar Ridge ◽  
Bone Augmentation ◽  
3 Dimensional ◽  
Ridge Augmentation ◽  
Combined Use

Background. Bone augmentation ensures a favorable 3-dimensional position of implants. Onlay grafting is one of the techniques in ridge augmentation, which can be performed with the use of xenogenous blocks. Methods. Three cases of the vertical and horizontal ridge are discussed, which were augmented using xenogenous blocks. The blocks were shaped in a favorable size and puzzled along the grafting area. All the gaps were filled with granular xenografts. The flaps were coronally advanced to obtain primary closure. Results. An average of 4.2-mm gain in width and 4.2-mm gain in height of the ridge was observed at the implantation stage. Conclusion. The outcomes of these cases could pave the way for suggesting xenograft blocks for augmenting wide areas of the alveolar ridge on average of 4 mm in width and height in selected cases as an alternative to standard autogenous blocks. Long-lasting xenograft ensures implant and lip support in the esthetic zone.

scholarly journals The Mechanical Properties and Biometrical Effect of 3D Preformed Titanium Membrane for Guided Bone Regeneration on Alveolar Bone Defect

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
So-Hyoun Lee ◽  
Jong-Hoon Moon ◽  
Chang-Mo Jeong ◽  
Eun-Bin Bae ◽  
Chung-Eun Park ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Regeneration ◽  
Bone Defect ◽  
Alveolar Bone ◽  
Three Dimensional ◽  
Compressive Load ◽  
Guided Bone Regeneration ◽  
Load Test ◽  
Mechanical Stiffness ◽  
Titanium Membrane

The purpose of this study is to evaluate the effect of three-dimensional preformed titanium membrane (3D-PFTM) to enhance mechanical properties and ability of bone regeneration on the peri-implant bone defect. 3D-PFTMs by new mechanically compressive molding technology and manually shaped- (MS-) PFTMs by hand manipulation were applied in artificial peri-implant bone defect model for static compressive load test and cyclic fatigue load test. In 12 implants installed in the mandibular of three beagle dogs, six 3D-PFTMs, and six collagen membranes (CM) randomly were applied to 2.5 mm peri-implant buccal bone defect with particulate bone graft materials for guided bone regeneration (GBR). The 3D-PFTM group showed about 7.4 times higher mechanical stiffness and 5 times higher fatigue resistance than the MS-PFTM group. The levels of the new bone area (NBA, %), the bone-to-implant contact (BIC, %), distance from the new bone to the old bone (NB-OB, %), and distance from the osseointegration to the old bone (OI-OB, %) were significantly higher in the 3D-PFTM group than the CM group (p<.001). It was verified that the 3D-PFTM increased mechanical properties which were effective in supporting the space maintenance ability and stabilizing the particulate bone grafts, which led to highly efficient bone regeneration.

Decellularized bone extracellular matrix in skeletal tissue engineering

2020 ◽  
Vol 48 (3) ◽  
pp. 755-764
Author(s):  
Benjamin B. Rothrauff ◽  
Rocky S. Tuan
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Tissue Regeneration ◽  
Animal Studies ◽  
Tumor Resection ◽  
Regenerative Capacity ◽  
Skeletal Tissue ◽  
Large Bone

Bone possesses an intrinsic regenerative capacity, which can be compromised by aging, disease, trauma, and iatrogenesis (e.g. tumor resection, pharmacological). At present, autografts and allografts are the principal biological treatments available to replace large bone segments, but both entail several limitations that reduce wider use and consistent success. The use of decellularized extracellular matrices (ECM), often derived from xenogeneic sources, has been shown to favorably influence the immune response to injury and promote site-appropriate tissue regeneration. Decellularized bone ECM (dbECM), utilized in several forms — whole organ, particles, hydrogels — has shown promise in both in vitro and in vivo animal studies to promote osteogenic differentiation of stem/progenitor cells and enhance bone regeneration. However, dbECM has yet to be investigated in clinical studies, which are needed to determine the relative efficacy of this emerging biomaterial as compared with established treatments. This mini-review highlights the recent exploration of dbECM as a biomaterial for skeletal tissue engineering and considers modifications on its future use to more consistently promote bone regeneration.

An innovative prone positioning system for advanced deformity and frailty in complex spine surgery

2020 ◽  
Vol 32 (2) ◽  
pp. 229-234
Author(s):  
Benjamin Kolb ◽  
John Large ◽  
Stuart Watson ◽  
Glyn Smurthwaite
Keyword(s):  
Ankylosing Spondylitis ◽  
Three Dimensional ◽  
Technical Note ◽  
Positioning System ◽  
Prone Positioning ◽  
Economic Implications ◽  
Potential Safety ◽  
Chest Deformity ◽  
Positioning Device ◽  
Skin Quality

The authors present a technical note for a prone positioning system developed to facilitate cervical extension osteotomy for ankylosing spondylitis in the presence of severe deformity and frailty. Chin-on-chest deformity represents one of the most debilitating changes of ankylosing spondylitis. Where the chin-brow angle approaches or exceeds 90°, prone positioning becomes problematic due to the fixed position of the head. Furthermore, the challenge is compounded where physiological deconditioning leads to frailty, and the side effects of medical therapies decrease muscle mass and skin quality. Conventional prone positioning equipment is not able to cater to all patients. A versatile system was developed using a 3D reconstruction to enable a positioning simulation and verification tool. The tool was used to comprehensively plan the perioperative episode, including spatial orientation and associated equipment. Three-dimensional printing was used to manufacture a bespoke positioning device that precisely matched the contours of the patient, reducing contact pressure and risk of skin injury. The authors were able to safely facilitate surgery for a patient whose deformity and frailty may otherwise have precluded this possibility. The system has potential safety and economic implications that may be of significant utility to other institutions engaging in complex spinal surgery.

Central ossifying fibroma of mandible

2020 ◽  
Vol 13 (12) ◽  
pp. e239286
Author(s):  
Kumar Nilesh ◽  
Prashant Punde ◽  
Nitin Shivajirao Patil ◽  
Amol Gautam
Keyword(s):  
Fibrous Tissue ◽  
Three Dimensional ◽  
Facial Asymmetry ◽  
Ossifying Fibroma ◽  
Mandible Reconstruction ◽  
Three Dimensional Printing ◽  
Osseous Lesion ◽  
Large Size ◽  
Dimensional Printing

Ossifying fibroma (OF) is a rare, benign, fibro-osseous lesion of the jawbone characterised by replacement of the normal bone with fibrous tissue. The fibrous tissue shows varying amount of calcified structures resembling bone and/or cementum. The central variant of OF is rare, and shows predilection for mandible among the jawbone. Although it is classified as fibro-osseous lesion, it clinically behaves as a benign tumour and can grow to large size, causing bony swelling and facial asymmetry. This paper reports a case of large central OF of mandible in a 40-year-old male patient. The lesion was treated by segmental resection of mandible. Reconstruction of the surgical defect was done using avascular fibula bone graft. Role of three-dimensional printing of jaw and its benefits in surgical planning and reconstruction are also highlighted.

scholarly journals Three-Dimensional Zirconia-Based Scaffolds for Load-Bearing Bone-Regeneration Applications: Prospects and Challenges

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3207
Author(s):  
Kumaresan Sakthiabirami ◽  
Vaiyapuri Soundharrajan ◽  
Jin-Ho Kang ◽  
Yunzhi Peter Yang ◽  
Sang-Won Park
Keyword(s):  
Bone Regeneration ◽  
Biological Activities ◽  
Three Dimensional ◽  
In Vivo Studies ◽  
High Mechanical Strength ◽  
Real World Applications ◽  
3D Fabrication ◽  
Dental Applications

The design of zirconia-based scaffolds using conventional techniques for bone-regeneration applications has been studied extensively. Similar to dental applications, the use of three-dimensional (3D) zirconia-based ceramics for bone tissue engineering (BTE) has recently attracted considerable attention because of their high mechanical strength and biocompatibility. However, techniques to fabricate zirconia-based scaffolds for bone regeneration are in a stage of infancy. Hence, the biological activities of zirconia-based ceramics for bone-regeneration applications have not been fully investigated, in contrast to the well-established calcium phosphate-based ceramics for bone-regeneration applications. This paper outlines recent research developments and challenges concerning numerous three-dimensional (3D) zirconia-based scaffolds and reviews the associated fundamental fabrication techniques, key 3D fabrication developments and practical encounters to identify the optimal 3D fabrication technique for obtaining 3D zirconia-based scaffolds suitable for real-world applications. This review mainly summarized the articles that focused on in vitro and in vivo studies along with the fundamental mechanical characterizations on the 3D zirconia-based scaffolds.

Influence of a Honeycomb Facing on the Flow Through a Stepped Labyrinth Seal

2000 ◽  
Vol 124 (1) ◽  
pp. 140-146 ◽  
Author(s):  
V. Schramm ◽  
K. Willenborg ◽  
S. Kim ◽  
S. Wittig
Keyword(s):  
Flow Field ◽  
Three Dimensional ◽  
Theoretical Work ◽  
Labyrinth Seal ◽  
Honeycomb Structure ◽  
Experimental Investigations ◽  
Labyrinth Seals ◽  
Numerical Predictions ◽  
Flow Through ◽  
Aero Engines

This paper reports numerical predictions and measurements of the flow field in a stepped labyrinth seal. The theoretical work and the experimental investigations were successfully combined to gain a comprehensive understanding of the flow patterns existing in such elements. In order to identify the influence of the honeycomb structure, a smooth stator as well as a seal configuration with a honeycomb facing mounted on the stator wall were investigated. The seal geometry is representative of typical three-step labyrinth seals of modern aero engines. The flow field was predicted using a commercial finite volume code with the standard k-ε turbulence model. The computational grid includes the basic seal geometry as well as the three-dimensional honeycomb structures.

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