scholarly journals Effects of Comorbid Fibromyalgia Syndrome on activities of daily living in multiple sclerosis patients

2020 ◽  
Vol 78 (9) ◽  
pp. 556-560
Author(s):  
Ersin Kasım ULUSOY
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Fibromyalgia Syndrome ◽  
Fibromyalgia Impact Questionnaire ◽  
Delayed Diagnosis ◽  
Admission Rates ◽  
Multiple Sclerosis Patients

ABSTRACT Objective: To investigate the frequency of Comorbid Fibromyalgia Syndrome and its effects on quality of life and activities of daily living without any known psychiatric problem (schizophrenia or bipolar disorder) or severe disability, other than depression, in patients with multiple sclerosis, which is known to be a chronic disease in young adults. Methods: The study included 103 patients diagnosed with multiple sclerosis, following McDonald criteria, who had relapsing remitting disease. The Fibromyalgia Impact Questionnaire, Beck Anxiety Inventory, Beck Depression Inventory, Pittsburgh Sleep Quality Index, Fatigue Severity Scale, and Multiple Sclerosis Quality of Life-54 were applied for all patients. Results were analyzed using statistical methods. Results: Mean age was 35.04±8.72 years in the study population. The Expanded Disability Status Scale (EDSS) score was 2.21±0.93. Comorbid Fibromyalgia Syndrome was detected in 20 patients (19.4%). The mean score of Multiple Sclerosis Quality of Life-54 was found to be significantly higher in multiple sclerosis patients with Comorbid Fibromyalgia Syndrome when compared to those without it (34.80±9.14 versus 71.67±13.95; p<0.05). Conclusion: These results indicate that increased frequency of Comorbid Fibromyalgia Syndrome in multiple sclerosis causes worsening in activities of daily living and quality of life, delayed diagnosis, disability progression, and increased admission rates. Questioning and appropriately managing Comorbid Fibromyalgia Syndrome in clinical practice are important to improve the quality of life in multiple sclerosis patients.

Symptomatic Treatment in Multiple Sclerosis

US Neurology ◽  
2013 ◽  
Vol 09 (01) ◽  
pp. 35
Author(s):  
Sandra Bigi ◽  
E Ann Yeh ◽  
◽  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Young Adults ◽  
Sexual Dysfunction ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Negative Impact ◽  
Treatment Options ◽  
Symptomatic Treatment

Multiple sclerosis (MS) is a progressive and disabling neurodegenerative disease that primarily affects young adults. Despite significant therapeutic advances in the prevention of relapses, individuals with MS experience a variety of symptoms, most notably fatigue, spasticity, depression, gait and balance difficulties, and sexual dysfunction. These symptoms may interfere with activities of daily living and have a negative impact on quality of life. This review discusses treatment options for these symptoms.

The reliability and validity of the Nottingham Extended Activities of Daily Living Scale in patients with multiple sclerosis

2002 ◽  
Vol 8 (5) ◽  
pp. 372-376 ◽  
Author(s):  
C R Nicholl ◽  
N B Lincoln ◽  
E D Playford
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Controlled Trial ◽  
Reliability And Validity ◽  
Quality Of Life Scale ◽  
Assessment And Treatment ◽  
Life Scale

Objective: To investigate whether the Nottingham Extended Activities of Daily Living Scale (EADL) is reliable and valid for the assessment of disability in patients with multiple sclerosis (MS). Design: Questionnaire measures were administered on two occasions four months apart. Subjects: A total of 240 patients recruited through a randomized controlled trial of cognitive assessment and treatment in MS. Measures: The Nottingham EADL, Guys Neurological Disability Scale (GNDS) and SF-36 quality of life scale. Results: The EADL items did not form a Guttman Scale (CR 0.8, CS 0.3). The EADL and its four subscales all had high internal consistency (α 0.72-0.94). Test-retest reliability was satisfactory (rs 0.81-0.90) with a mean difference in scores on the two occasions of 0.29. Factor analysis generally supported the subscale structure. There were significant but weak correlations with quality of life measures. Conclusions: The EADL shows promise for the assessment of disability in MS, but the range of items needs to be extended. Further evaluation of the scale seems warranted.

Symptomatic Treatment in Multiple Sclerosis

2013 ◽  
Vol 8 (2) ◽  
pp. 130
Author(s):  
Sandra Bigi ◽  
E Ann Yeh ◽  
◽  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Young Adults ◽  
Sexual Dysfunction ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Negative Impact ◽  
Treatment Options ◽  
Symptomatic Treatment

Multiple sclerosis (MS) is a progressive and disabling neurodegenerative disease that primarily affects young adults. Despite significant therapeutic advances in the prevention of relapses, individuals with MS experience a variety of symptoms, most notably fatigue, spasticity, depression, gait and balance difficulties and sexual dysfunction. These symptoms may interfere with activities of daily living and have a negative impact on quality of life. This review discusses treatment options for these symptoms.

Pain in multiple sclerosis: a clinical and instrumental approach

2008 ◽  
Vol 14 (4) ◽  
pp. 506-513 ◽  
Author(s):  
MG Grasso ◽  
A Clemenzi ◽  
A Tonini ◽  
L Pace ◽  
P Casillo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Rating Scale ◽  
Negative Impact ◽  
Short Form ◽  
Structured Interview ◽  
Significant Difference

Background Pain is a frequent and disabling symptom in multiple sclerosis (MS) patients. In this study we assess the frequency and intensity of pain, as well as its impact on the quality of life and activities of daily living, in a sample of MS patients. Methods One hundred and twenty eight MS patients underwent a neurological examination, a structured interview designed to assess pain, and a Medical Outcome 36-item Short Form Health Survey. Functional status was assessed by means of the Barthel Index (BI) and Rivermead Mobility Index. We also assessed the presence of depression, by means of the Montgomery and Asberg Depression Rating Scale, and fatigue, by means of the Fatigue Severity Scale. An algometer was used to measure thermal and discomfort thresholds in all of the patients and a group of 61 age- and sex-matched healthy subjects. Results Pain was present in 61 patients. No differences were found between patients with and those without pain in disease duration, disease form or Expanded Disability Status Scale and its functional systems. Patients with pain had a lower vitality score ( p = 0.008), mental health score ( p = 0.03) and physical ( p < 0.001) and mental composite scores ( p = 0.01) than patients without pain. Furthermore, there was a significant difference between patients with and those without pain in the BI ( p = 0.04). Both thermal and discomfort thresholds, as assessed by means of the algometer, were statistically lower in MS patients than in controls, whereas no difference was observed between patients with and those without pain. There was a statistically significant improvement in the thermal threshold in patients with pain who were treated pharmacologically when compared with those who were not treated ( p = 0.049). Conclusion The results of this study provide further evidence of the negative impact that the presence of pain has on both the quality of life and activities of daily living in MS patients. The lower thermal and discomfort thresholds observed in our MS patients, compared with controls, may represent a predisposition to develop pain during the course of the disease.

Sign in / Sign up

Export Citation Format

Share Document