scholarly journals The chemistry of Brazilian Leguminosae. LX. Indolylacetic acid from Tachigalia paniculata

1982 ◽  
Vol 12 (4) ◽  
pp. 805-807
Author(s):  
Silvia M. C. Dias ◽  
◽  
José G. S. Maia ◽  
Zenaide S. Ferreira ◽  
Otto R. Gottlieb ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Ethanolic Extract ◽  
Indolylacetic Acid ◽  
Indolyl Acetic Acid

Abstract The ethanolic extract of trunk wood of Tachigalia paniculata Ducke (Leguminosae-Caesalpinioideae) was found to contain substantial quantities of 2-(3-indolyl)-acetic acid.

scholarly journals Effect of Ascorbic Acid and Indolyl Acetic Acid on Regeneration of Willow Branches and Germination

Nature ◽  
1936 ◽  
Vol 137 (3467) ◽  
pp. 618-618 ◽  
Author(s):  
W. DAVIES ◽  
G. A. ATKINS ◽  
P. C. B. HUDSON
Keyword(s):  
Ascorbic Acid ◽  
Acetic Acid ◽  
Indolyl Acetic Acid

scholarly journals A Original Article ANALGESIC ACTIVITY OF BARK AND LEAVES OF FICUS RELIGIOSA L. FROM NEPAL

2020 ◽  
pp. 32-35
Author(s):  
DHARMA RAJ MARASINI ◽  
JITENDRA PANDEY ◽  
LAXMAN PAUDEL SHARMA ◽  
LAXMI PAUDEL ◽  
ROSHNI GYAWALI ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Analgesic Activity ◽  
Test Group ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Latency Time ◽  
Hot Plate ◽  
Ficus Religiosa ◽  
Standard Drug ◽  
Ethanolic Extracts

Objective: Because of adverse side effects, caused by NSAIDs, tolerance, and dependence induced by opiates, the use of these analgesic agents has not been successful in all cases. Therefore, alternative analgesic drugs from plant sources are the new target now days. The objective of this study was to evaluate the analgesic activity of ethanolic extracts of stem barks and leaves of Ficus religiosa. Methods: The analgesic activity of ethanolic extract of stem barks and leaves was evaluated in the Swiss albino mice model using acetic acid-induced writing response and Eddy’s hot plate method. Analgesic activity was demonstrated with the percentage inhibition of acetic acid induced writings and the percentage increased in latency time of paw licking. The potency of test extracts was compared with standard drug, Diclofenac. Results: Ethanolic extract of leaves and bark of F. religiosa showed potential analgesic activity from both methods. From Eddy’s hot plate model, it was observed that the percentage of increased latency time at 90 min by ethanolic extract of leaves and stem bark was found to be 70.81 % (8.54 min) and 70.78 % (8.53 min) respectively at a dose of 400 mg/kg. Both of these results are statistically significant (p<0.05) as compared to the test group. Furthermore, both of these extracts showed the dose-dependent and time-dependent increased in latency time and these results are compared to that of standard drug Diclofenac. Similarly, ethanolic extract of leaves and stem at 400 mg/kg significantly inhibited the number of writhings induced by acetic acid. The percentage inhibition of writhings by ethanolic extract of leaves at a dose of 400 mg/kg was 68.47 % which was similar to that of standard drug Diclofenac (68.47 %). However, ethanolic extract of bark showed relatively lower percentage inhibition (60.79 %) as compared to leaf extract and standard, but the result was significant as compared to that of the test group (p<0.05). Conclusion: Ethanolic extracts of F. religiosa stem bark and leaf possess both central and peripheral analgesic properties and these effects may be beneficial for the management of pain.

scholarly journals Analgesic and Anti-inflammatory Activities of Ethanolic Extract of Clerodendrum inerme (L.) Gaertn.

2015 ◽  
Vol 17 (1) ◽  
pp. 62-66 ◽  
Author(s):  
Dipa Khanam ◽  
Debashish Deb ◽  
Shrabanti Dev ◽  
Masum Shahriar ◽  
Asish K Das ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Skin Diseases ◽  
Diclofenac Sodium ◽  
Latency Period ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Pharmaceutical Journal ◽  
Edema Formation ◽  
Standard Drug ◽  
Anti Inflammatory

Clerodendrum inerme (L.) Gaertn. (Verbenaceae) is very popular among the traditional practitioners in Bangladesh for the treatment of local pain and inflammation, skin diseases, topical burns etc. However, so far no scientific study has been carried out which may support its uses in traditional medicine. In the present study, we evaluated the possible analgesic and anti-inflammatory activities of the ethanol extract of C. inerme for the first time. Analgesic activity was assessed by using acetic acid-induced writhing and heat-induced pain in mice and anti-inflammatory activity using xylene-induced ear edema in mice at the doses of 250 and 500 mg/kg body weight. The extract significantly (P< 0.05) attenuated the acetic acid-induced writhing with the highest activity being observed at 500 mg/kg b.w. (45.83%) comparable to that of diclofenac sodium (57.64%), the standard drug. A significant dosedependent increase (P< 0.05) of the latency period was also observed in hot plate method. In the xylene-induced inflammation assay, the extract showed significant (P<0.05) and dose dependant inhibitory effect on the edema formation. These findings indicate that the extract has significant analgesic and anti-inflammatory activities which support the folkloric claim of this plant and thus it has a great potential as source of natural products-derived drug. DOI: http://dx.doi.org/10.3329/bpj.v17i1.22317 Bangladesh Pharmaceutical Journal 17(1): 62-66, 2014

scholarly journals The Effect of Auxins on the Binding of Pectin Methylesterase to Cell Wall Preparations

1957 ◽  
Vol 10 (4) ◽  
pp. 426 ◽  
Author(s):  
KT Glasziou
Keyword(s):  
Cell Wall ◽  
Acetic Acid ◽  
Jerusalem Artichoke ◽  
Pectin Methylesterase ◽  
Naphthalene Acetic Acid ◽  
Dichlorophenoxyacetic Acid ◽  
Indolylacetic Acid ◽  
2,4 Dichlorophenoxyacetic Acid

It is shown that the plant auxins 3�indolylacetic acid, 2,4-dichlorophenoxyacetic acid, and a�naphthalene acetic acid are effective in binding pectin methylesterase (PME) to cell wall preparations from tobacco pith and tubers of the Jerusalem artichoke.

scholarly journals Analgesic Effect of Ethanolic Extract of Seeds and Leaves of Coriandrum Sativum on Swiss Albino Mice

2021 ◽  
Vol 9 (02) ◽  
pp. 50-55
Author(s):  
Chandrajeet Kumar Yadav ◽  
Poonam Tiwari ◽  
Roshan Mehta ◽  
Amit Kumar Shrivastava ◽  
Anjan Palikhey
Keyword(s):  
Acetic Acid ◽  
Analgesic Effect ◽  
International Association ◽  
Emotional Experience ◽  
Ethanolic Extract ◽  
Coriandrum Sativum ◽  
Hot Plate ◽  
Plate Method ◽  
Swiss Albino Mice ◽  
Albino Mice

INTRODUCTION: Pain has been described by the International Association for the Study of Pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Although NSAIDS and OPIOIDS are available for the treatment, still pain (chronic) is major problem. The present study was designed to study the analgesic effect of ethanolic extract of Coriandrum sativum using hot plate method and acetic acid induced writhing method in experimental animals (Swiss albino mice). MATERIAL AND METHODS:The analgesic effect of leaves and seeds of Coriandrum sativum was assessed using hot plate method and acetic acid induced writhing method in Swiss albino mice. The animals were treated with the ethanolic extract of leaves and seeds of Coriandrum sativum orally at two doses of 100, 500 mg/kg body weight after electric heat and acetic acid induced pain in mice. RESULTS: The study showed that ethanolic extract of leaves and seeds of Coriandrum sativum presented significant (p<0.05) and (p<0.05) analgesic activity in mice simultaneously. The data were analyzed by one-way ANOVA followed by Dunette's multiple comparison test. The results demonstrate that ethanolic extract of leaves and seeds of Coriandrum sativum has got analgesic potential. CONCLUSION: The results demonstrate that ethanolic extract of leaves and seeds of Coriandrum sativum has got significant analgesic effect.

scholarly journals Potential of Mimosa pudica leaf in the treatment of ulcerative colitis in rat

2018 ◽  
Vol 13 (3) ◽  
pp. 241
Author(s):  
Bharati Zaware ◽  
Ritu Gilhotra ◽  
Sanjay Ravindra Chaudhari
Keyword(s):  
Ulcerative Colitis ◽  
Acetic Acid ◽  
Acetic Acid Solution ◽  
Video Clip ◽  
Ethanolic Extract ◽  
Mimosa Pudica ◽  
Ulcer Index ◽  
Colon Tissue ◽  
Standard Drug ◽  
Full Screen

<p class="Abstract">The aim of present investigation was to validate its folk use in the treatment of ulcerative colitis in the rat model. Sprague Dawley rats were divided into nine groups with six animals in each group. The rats received seven days of pretreatment with chloroform, ethyl acetate or ethanolic extract of <em>Mimosa pudica</em>. For induction of ulcerative colitis, rats were administered with 2 mL of 4% acetic acid solution intrarectally. Ulcer index, macroscopical study of the colon, myeloperoxidase and malondialdehyde levels in colon tissue and blood, and histopathology of the colon tissue were studied. Intrarectal instillation of acetic acid caused increased ulcer index, colonic myeloperoxidase and malondialdehyde. Pretreatment with <em>M. pudica</em> ethanolic extract (400 mg/kg) significantly lowered the ulcer index, colonic myeloperoxidase and malondialdehyde as compared with the standard drug prednisolone. The present investigation demonstrates that the ethanol extract of <em>M. pudica</em> leaf is effective in the treatment of ulcerative colitis.</p><p class="Abstract"><strong>Video Clip of Methodology:</strong></p><p class="Abstract">Embedding or block making: 24 sec   <a href="https://www.youtube.com/v/Y1I4tKYMLsE">Full Screen</a>   <a href="https://www.youtube.com/watch?v=Y1I4tKYMLsE">Alternate</a></p><p class="Abstract">Tissue processing: 19 sec   <a href="https://www.youtube.com/v/7nYpxL2qPhg">Full Screen</a>   <a href="https://www.youtube.com/watch?v=7nYpxL2qPhg">Alternate</a></p><p class="Abstract">Section cutting: 33 sec   <a href="https://www.youtube.com/v/_amFL9kNLBw">Full Screen</a>   <a href="https://www.youtube.com/watch?v=_amFL9kNLBw">Alternate</a></p>

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