scholarly journals Molecular analysis of the N gene of canine distemper virus in dogs in Brazil

2007 ◽  
Vol 59 (3) ◽  
pp. 654-659 ◽  
Author(s):  
J.G. Castilho ◽  
P.E. Brandão ◽  
P. Carnieli Jr ◽  
R.N. Oliveira ◽  
C.I. Macedo ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Phylogenetic Analysis ◽  
Nervous System ◽  
Molecular Analysis ◽  
Canine Distemper Virus ◽  
Nucleotide Identity ◽  
N Gene ◽  
Canine Distemper ◽  
Gene Sequences ◽  
Rt Pcr

Eleven central-nervous-system samples collected from stray dogs between 2000 and 2004 were found positive by RT-PCR, which amplified a 480bp fragment of the N gene of canine distemper virus (CDV). Phylogenetic analysis based on partial N-gene sequences showed four major clusters. All dog strains segregated into cluster I, with a mean nucleotide identity of 95.8% and 95.6% with the Onderstepoort and Lederle vaccine strains, respectively. Cluster II contained all the raccoon-related strains, cluster III Orient strains and Cluster IV the Onderstepoort and Lederle vaccine strains, with a mean nucleotide identity of 99.7% between them. This is the first report of phylogenetic analysis of CDV strains in Brazil.

scholarly journals The nervous form of canine distemper

2018 ◽  
Vol 13 (2) ◽  
pp. 125-136
Author(s):  
Alice Fernandes Alfieri ◽  
Alexandre Mendes Amude ◽  
Amauri Alcindo Alfier
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Canine Distemper Virus ◽  
Demyelinating Disease ◽  
Clinical Course ◽  
Systemic Infection ◽  
Canine Distemper ◽  
Systemic Involvement ◽  
Clinical Syndromes ◽  
The Central Nervous System

Canine distemper is a systemic infection, frequently lethal in dogs. The canine distemper virus(CDV) causes a persistent infection within the central nervous system resulting in aprogressive, multifocal demyelinating disease. In dogs, CDV infection may lead togastrointestinal and/or respiratory signs, frequently with central nervous system involvement.Myoclonus has been a common and characteristic sign observed in dogs with distemperencephalomyelitis. However, the nervous form of distemper may occur in the absence ofmyoclonus and systemic involvement. This review will point the clinical course and theneurological signs of nervous distemper, as well the clinical syndromes of CDV infection,neuropathology of acute and chronic demyelination, and diagnostic aids of CDVencephalomyelitis.

Studies on canine distemper virus persistence in the central nervous system

1995 ◽  
Vol 89 (5) ◽  
pp. 438-445 ◽  
Author(s):  
Cornelia F. M�ller ◽  
Rosmarie S. Fatzer ◽  
Karin Beck ◽  
Marc Vandevelde ◽  
Andreas Zurbriggen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Canine Distemper Virus ◽  
Canine Distemper ◽  
Virus Persistence ◽  
The Central Nervous System

scholarly journals Expression of canine distemper virus receptor nectin-4 in the central nervous system of dogs

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Watanyoo Pratakpiriya ◽  
Angeline Ping Ping Teh ◽  
Araya Radtanakatikanon ◽  
Nopadon Pirarat ◽  
Nguyen Thi Lan ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Canine Distemper Virus ◽  
Canine Distemper ◽  
Virus Receptor ◽  
The Central Nervous System

scholarly journals Early T cell response in the central nervous system in canine distemper virus infection

1999 ◽  
Vol 97 (1) ◽  
pp. 45-56 ◽  
Author(s):  
A. Tipold ◽  
P. Moore ◽  
A. Zurbriggen ◽  
I. Burgener ◽  
G. Barben ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
T Cell ◽  
Virus Infection ◽  
Cell Response ◽  
Canine Distemper Virus ◽  
T Cell Response ◽  
Canine Distemper ◽  
The Central Nervous System
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