scholarly journals Serological follow-up of Trypanosoma cruzi infection from 1987 to 1994 in 32 counties of the State of Jalisco, Mexico: preliminary report

1995 ◽  
Vol 11 (3) ◽  
pp. 501-505
Author(s):  
Francisco Trujillo-Contreras ◽  
Maria Angeles V. Yerenas
Keyword(s):  
Immune Response ◽  
South America ◽  
Trypanosoma Cruzi ◽  
Preliminary Report ◽  
The State ◽  
Laboratory Techniques ◽  
The University ◽  
Mexican Strains ◽  
Cruzi Infection

In 1987 the University of Guadalajara performed a seroepidemiological survey on the prevalence of Chagas’ disease in the 124 counties of the State of Jalisco, Mexico, arriving at a rate of 21.6 per 100 inhabitants. From December 1993 to June 1994, we studied 2238 individuals from 32 rural counties in this State. Of these, we found 276 positives (12.33%) and 1962 negatives (87.66%). Nevertheless, the series of serological differences found are very striking, since out of the 655 individuals that were seropositive in 1987, we noted that 276 individuals remained positive, while 50 individuals (7.63%) became negative. There were no flaws in the laboratory techniques. We believe that either the immune response of Mexicans is different or that the virulence of the Mexican strains of Trypanosoma cruzi may be not as great as that in the South America countries.

Dynamics of T Cells Repertoire During Trypanosoma cruzi Infection and its Post-Treatment Modulation

2019 ◽  
Vol 26 (36) ◽  
pp. 6519-6543 ◽  
Author(s):  
Adriana Egui ◽  
Paola Lasso ◽  
Elena Pérez-Antón ◽  
M. Carmen Thomas ◽  
Manuel Carlos López
Keyword(s):  
Immune Response ◽  
Trypanosoma Cruzi ◽  
Chagas Disease ◽  
Cardiac Tissue ◽  
Acute Infection ◽  
Clinical Status ◽  
Chronic Phase ◽  
Parasite Load ◽  
Chronic Patients ◽  
Cruzi Infection

Chagas disease courses with different clinical phases and has a variable clinical presentation and progression. The acute infection phase mostly exhibits a non-specific symptomatology. In the absence of treatment, the acute phase is followed by a chronic phase, which is initially asymptomatic. This chronic asymptomatic phase of the disease is characterized by a fragile balance between the host’s immune response and the parasite replication. The loss of this balance is crucial for the progression of the sickness. The virulence and tropism of the T. cruzi infecting strain together to the inflammation processes in the cardiac tissue are the main factors for the establishment and severity of the cardiomyopathy. The efficacy of treatment in chronic Chagas disease patients is controversial. However, several studies carried out in chronic patients demonstrated that antiparasitic treatment reduces parasite load in the bloodstream and leads to an improvement in the immune response against the Trypanosoma cruzi parasite. The present review is mainly focused on the cellular patterns associated to the clinical status and the evolution of the disease in chronic patients, as well as the effectiveness of the treatment related to T. cruzi infection control. Therefore, an emphasis is placed on the dynamics of specific-antigens T cell subpopulations, their memory and activation phenotypes, their functionality and their contribution to pathogenesis or disease control, as well as their association with risk of congenital transmission of the parasite.

scholarly journals Etiological treatment of young women infected with Trypanosoma cruzi, and prevention of congenital transmission

2009 ◽  
Vol 42 (5) ◽  
pp. 484-487 ◽  
Author(s):  
Sergio Sosa-Estani ◽  
Estela Cura ◽  
Elsa Velazquez ◽  
Cristina Yampotis ◽  
Elsa Leonor Segura
Keyword(s):  
Trypanosoma Cruzi ◽  
Young Women ◽  
Serological Tests ◽  
Congenital Transmission ◽  
Cruzi Infection ◽  
Efficacy Of Treatment

The objective was to detect Trypanosoma cruzi infection in 32 children in Salta, Argentina, born to 16 chronically infected young women who were treated with benznidazole. Tests were performed to assess the efficacy of treatment after 14 years. At the end of the follow up, 87.5% of the women were non-reactive to EIA tests, 62.5% to IHA and 43.8% to IFA. 62.5% of the women were non-reactive according to two or three serological tests. No infected children were detected among the newborns of mothers treated before their pregnancy.

scholarly journals Investigation regarding the presence of Trypanosoma cruzi in triatomines and humans in rural households in the State of Paraná, southern Brazil

2021 ◽  
Vol 10 (10) ◽  
pp. e54101018366
Author(s):  
Ana Paula de Abreu ◽  
Hevillyn Fernanda Lucas da Silva ◽  
Marcella Paula Mansano Sarto ◽  
Giullia Ferreira Iunklaus ◽  
João Vitor Trovo ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Rural Households ◽  
Etiologic Agent ◽  
The State ◽  
Molecular Techniques ◽  
Triatoma Infestans ◽  
Southern Brazil ◽  
The North ◽  
Intestinal Contents ◽  
Cruzi Infection

Trypanosoma cruzi, the etiologic agent of Chagas disease (CD), is transmitted by hematophagous insects belonging to the subfamily Triatominae. After elimination of Triatoma infestans, the infestation of human dwellings by secondary species of vectors continues to pose a risk of transmission of the parasite. Our aim was to investigate the T. cruzi presence in triatomines and humans in rural households in the State of Paraná, southern Brazil. The capture of the insects was carried out by technicians of the municipalities after residents reported the outbreak. Five residents and 27 triatomines captured in four municipalities in the North and Midwest of the state were evaluated. The research of T. cruzi was carried out using parasitological, serological, and molecular techniques, in human blood, excreta, intestinal contents and insect macerate. Panstrongylus megistus, P. geniculatus and Triatoma sp.  were identified. Ten specimens of P. megistus were captured in a house in Mandaguari with five residents and presented an infection rate of 70% for T. cruzi like. All residents tested negative for T. cruzi infection. Another 15 P. megistus were captured in the peridomicile in Janiópolis and had 100.0% positivity. The only adult specimen of P. geniculatus captured in the intradomicile in Amaporã, as well as the nymph of Triatoma in the peridomicile in Paiçandu, were negative. The finding of P. megistus naturally infected by T. cruzi in households in rural area of Paraná demonstrates a potential risk of vector transmission of CD in these regions.

scholarly journals Seroprevalence of Trypanosoma cruzi infection among blood donors in the state of Bahia, Brazil

2019 ◽  
Vol 52 ◽  
Author(s):  
Diego Lopes Paim Miranda ◽  
Gilmar Ribeiro Jr ◽  
Fernanda Cardoso Lanza ◽  
Fred Luciano Neves Santos ◽  
Renato Barbosa Reis ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Blood Donors ◽  
The State ◽  
Cruzi Infection

scholarly journals Characteristics of Triatomine infestation and natural Trypanosoma cruzi infection in the State of Rio Grande do Norte, Brazil

2016 ◽  
Vol 49 (1) ◽  
pp. 57-67 ◽  
Author(s):  
Andressa Noronha Barbosa-Silva ◽  
Antonia Cláudia Jácome da Câmara ◽  
Kiev Martins ◽  
Daniela Ferreira Nunes ◽  
Pedro Igor Câmara de Oliveira ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Rio Grande ◽  
The State ◽  
Cruzi Infection

scholarly journals Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole

2020 ◽  
Vol 14 (9) ◽  
pp. e0008726
Author(s):  
Claudia Magalhães Calvet ◽  
Tatiana Araújo Silva ◽  
Diane Thomas ◽  
Brian Suzuki ◽  
Ken Hirata ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Chagas Disease ◽  
Long Term Follow Up ◽  
Cruzi Infection

scholarly journals Course of Chronic Trypanosoma cruzi Infection after Treatment Based on Parasitological and Serological Tests: A Systematic Review of Follow-Up Studies

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0139363 ◽  
Author(s):  
Yanina Sguassero ◽  
Cristina B. Cuesta ◽  
Karen N. Roberts ◽  
Elizabeth Hicks ◽  
Daniel Comandé ◽  
...  
Keyword(s):  
Systematic Review ◽  
Trypanosoma Cruzi ◽  
Serological Tests ◽  
Follow Up Studies ◽  
Cruzi Infection

scholarly journals Preliminary Report on Cherokee County, Oklahoma Archeology

2001 ◽  
Author(s):  
Lynn E. Howard
Keyword(s):  
Preliminary Report ◽  
The State ◽  
Illinois River ◽  
Preliminary Survey ◽  
University Of Oklahoma ◽  
The University

Cherokee County is the latest in the state to have its prehistoric conditions investigated by the Department of Anthropology at the University of Oklahoma, in conjunction with the Federal Works Projects Administration. The preliminary survey located several likely sites. Work was begun in July 1939 on a village site and mound located at the junction of Barren Fork Creek and the Illinois River, on a farm owned by M.L. Brackett. It is located in the southwest quarter of Section 18, Township 16 North, Range 23 East. The symbol for this site is Ck. Bk. 1 (Cherokee County, Brackett site.

scholarly journals Excavation at the new Brisbane Airport site (LB:C69): evidence for early mid-Holocene coastal occupation in Moreton Bay, SE Queensland

1987 ◽  
Vol 4 ◽  
pp. 54-79 ◽  
Author(s):  
J. Hall ◽  
Ian Lilley
Keyword(s):  
Preliminary Report ◽  
The State ◽  
Subsequent Test ◽  
Moreton Bay ◽  
Queensland Department ◽  
The University ◽  
Airport Site ◽  
Stone Artefact

In 1980, during excavation of a floodway connected with the construction of the New Brisbane Airport, stone artefacts were observed within the sediments by Mr. Bill Ward, CSIRO Soils Division. His alerting of the state authorities led to further investigations by one of the authors (JH). Such interest was sparked by the fact that, on geomorphic grounds, the site promised an antiquity of at least 4000 years BP. Subsequent test excavation (by JH) in 1984 yielded an in situ stone artefact assemblage with a backed blade component which was associated with an anomalous date of about 1,100 B.P. In order to resolve the problem posed by this association, further excavation was undertaken in July-August 1987 by members of the Field Archaeology class (AY225) of the University of Queensland Department of Anthropology and Sociology under the supervision of Jay Hall and Ian Lilley. This paper is a preliminary report combining findings of both excavations and offers substantive support for an early mid-Holocene Aboriginal occupation of the shores of Moreton Bay. 

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