The purpose of this paper is to investigate mass and heat transfer in the process of film condensation of vapor-air mixture for non-cryogenic fluids flow in a small vertical tube. A two-phase mathematical model is developed to model the mixture and liquid film. The governing equations for mixture and liquid-film have been resolved using a numerical method. Furthermore, this phenomenon analyzed is linked to a steady-state. Therefore, the development of numerical codes allows us to investigate the effect of implicated parameters on this phenomenon. Ethanol and methanol as non-cryogenic typical working fluids are realized for a good understanding of the heat and mass transfer mechanism during condensation. In this way, several effects of influencing parameters were examined. The predicted results showed a good agreement with experimental data.