scholarly journals Cost-Effectiveness of the National Screening Program for Hepatitis C Virus in the General Population and the High-Risk Groups

2008 ◽  
Vol 215 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Junichiro Nakamura ◽  
Kenshi Terajima ◽  
Yutaka Aoyagi ◽  
Kouhei Akazawa
Keyword(s):  
Hepatitis C Virus ◽  
Cost Effectiveness ◽  
Hepatitis C ◽  
High Risk ◽  
General Population ◽  
Screening Program ◽  
Risk Groups

scholarly journals Performance and modification of EGCRISC among hepatitis C virus high-risk groups

2020 ◽  
Vol 148 ◽  
Author(s):  
E. M. El-Ghitany ◽  
Y. M. Alkassabany ◽  
A. G. Farghaly
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
High Risk ◽  
Sex Workers ◽  
Screening Tool ◽  
Risk Groups ◽  
Hcv Infection ◽  
Human Immune Deficiency Virus ◽  
Hiv Patients ◽  
Increased Risk

Abstract We have previously shown that the Egyptian Hepatitis C Virus Risk Score (EGCRISC), an Egyptian hepatitis C virus (HCV) risk-based screening tool, to be valid and cost-effective. Certain behaviours, occupations and diseases have been shown to be associated with an increased risk of exposure to HCV infection and constitute a major population reservoir of HCV infection. This study investigated the efficacy of EGCRISC in selected high-risk groups by testing 863 participants from four groups: slaughterhouse workers, illicit drug users (IDUs), female sex workers and human immune deficiency virus (HIV) patients. Data for this study were collected on EGCRISC and another pre-designed risk factor questionnaire. Sera were tested for HCV antibodies by ELISA. EGCRISC, at lower cut-off points, showed significantly good performance (P < 0.05) in all four groups except for females <45 years, but was reliable in detecting HCV cases (sensitivity: 84.21% and negative predictive value: 94.5%). Specific scores for IDUs and HIV patients were developed that showed high accuracy (P < 0.001). A modified EGCRISC for high-risk groups (EGCRISC-HRGs) was shown to be a valid tool that is recommended for use in high-risk populations if no other specific screening tool is available or universal screening is applied. EGCRISC for IDUs (EGCRISC-IDUs) and EGCRISC for HIV patients (EGCRISC-HIV) are useful tools for preselecting potentially HCV-infected cases for further testing in settings where serological analysis is not readily available or accessible.

scholarly journals Prevalence of hepatitis C infection among the general population and high-risk groups in the EU/EEA: a systematic review update

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ru Han ◽  
Junwen Zhou ◽  
Clément François ◽  
Mondher Toumi
Keyword(s):  
Systematic Review ◽  
Hepatitis C ◽  
High Risk ◽  
General Population ◽  
Risk Groups ◽  
Hepatitis C Infection ◽  
The Eu

Cost-effectiveness of one-time screening for hepatitis C virus infection in Korean general population

2018 ◽  
Vol 68 ◽  
pp. S326
Author(s):  
K.-A. Kim ◽  
W. Chung ◽  
H.Y. Choi ◽  
E.S. Jang ◽  
M. Ki ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Cost Effectiveness ◽  
Hepatitis C ◽  
General Population ◽  
Virus Infection ◽  
Hepatitis C Virus Infection

scholarly journals Prevalence of hepatitis C infection among the general population and high-risk groups in the EU/EEA: A systematic review update

2019 ◽  
Author(s):  
Ru HAN ◽  
Junwen ZHOU ◽  
Clément François N ◽  
Mondher Toumi
Keyword(s):  
Hepatitis C ◽  
High Risk ◽  
General Population ◽  
Risk Groups ◽  
Epidemiological Studies ◽  
Resource Utilisation ◽  
European Economic Area ◽  
The European Union ◽  
Hepatitis C Infection ◽  
Healthcare Resource Utilisation

Abstract Background: Although significant improvement in efficacy measured by a sustained virological response, the high acquisition costs of direct-acting antivirals limit the access for patients and influence the costs of healthcare resource utilisation in hepatitis C. It is important to have the latest estimates of prevalence, especially in high-risk groups, for cost of illness, cost-effectiveness and budget impact studies. Methods: Original studies on the estimates of the prevalence among general and high-risk populations in the European Union/European Economic Area (EU/EEA) were retrieved from Medline and Embase for the period from 2015 to 2018. All included studies were evaluated for risk of selection bias and summarised together in a narrative form. Results from previous reviews and updated searches were compared per country among different populations, respectively. Results: Among the 3871 studies identified, 46 studies were included: 20 studies were used for the estimate of the general population; 3 for men who have sex with men (MSM); 6 for prisoners; and 17 for people who inject drugs (PWID). Compared with the results reported in previous systematic reviews, the updated estimates were lower than previously in most available countries. Anti-HCV general population prevalence estimates ranged from 0.54% to 1.50% by country. The highest prevalence of anti-HCV was found among PWID (range of 7.90% - 82.00%), followed by prisoners (7.00% - 41.00%), HIV-positive MSM (1.80% - 7.10%), HIV-negative MSM (0.20% - 1.80%), pregnant women (0.10% - 1.32%) and first-time blood donors (0.03% - 0.09%). Conclusions: Our study highlights the heterogeneity in anti-HCV prevalence across different population groups in EU/EEA. The prevalence also varies widely between European countries. There are many countries that are not represented in our results, highlighting the need for the development of robust epidemiological studies.

Prevalence of hepatitis C virus genotypes and subtypes in Lebanese population and major high risk groups

2017 ◽  
Vol 18 (2) ◽  
pp. 114-117 ◽  
Author(s):  
Antoine Abou Rached ◽  
Cesar Yaghi ◽  
Leda Khalil ◽  
Jowana Saba ◽  
Walid Ammar
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
High Risk ◽  
Risk Groups ◽  
Lebanese Population ◽  
Virus Genotypes ◽  
Hepatitis C Virus Genotypes

Mode of hepatitis C virus infection, epidemiology, and chronicity rate in the general population and risk groups

1996 ◽  
Vol 41 (S12) ◽  
pp. 27S-40S ◽  
Author(s):  
Hans L. Tillmann ◽  
Michael P. Manns
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
General Population ◽  
Virus Infection ◽  
Risk Groups ◽  
Hepatitis C Virus Infection

High prevalence of hepatitis C virus infection and genotype distribution among general population, blood donors and risk groups

2006 ◽  
Vol 6 (3) ◽  
pp. 198-204 ◽  
Author(s):  
Mohammed N. Khaja ◽  
Chandra Madhavi ◽  
Rekha Thippavazzula ◽  
Farees Nafeesa ◽  
Aejaz M. Habib ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
General Population ◽  
Virus Infection ◽  
Blood Donors ◽  
Risk Groups ◽  
Genotype Distribution ◽  
Hepatitis C Virus Infection ◽  
High Prevalence

Cost Effectiveness of Hepatitis C-Related Interventions Targeting Substance Users and Other High-Risk Groups

2012 ◽  
Vol 30 (11) ◽  
pp. 1015-1034 ◽  
Author(s):  
Ava John-Baptiste ◽  
Man Wah Yeung ◽  
Victoria Leung ◽  
Gabrielle van der Velde ◽  
Murray Krahn
Keyword(s):  
Cost Effectiveness ◽  
Hepatitis C ◽  
High Risk ◽  
Risk Groups ◽  
Substance Users

Prevalence of hepatitis C virus infection among high-risk groups in Iran: a systematic review and meta-analysis

Public Health ◽  
2018 ◽  
Vol 161 ◽  
pp. 90-98 ◽  
Author(s):  
S. Nematollahi ◽  
E. Ayubi ◽  
A. Almasi-Hashiani ◽  
K. Mansori ◽  
Y. Moradi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
High Risk ◽  
Virus Infection ◽  
Meta Analysis ◽  
Risk Groups ◽  
Hepatitis C Virus Infection
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