Epidemic Outbreaks, Diagnostics, and Control Measures of the H5N1 Highly Pathogenic Avian Influenza in the Kingdom of Saudi Arabia, 2007–08

2010 ◽  
Vol 54 (s1) ◽  
pp. 350-356 ◽  
Author(s):  
Huaguang Lu ◽  
Mahmoud Moussa Ismail ◽  
Owais Ahmed Khan ◽  
Yousef Al Hammad ◽  
Salah Shaban Abdel Rhman ◽  
...  
2010 ◽  
Vol 5 (s1) ◽  
pp. e59-e60
Author(s):  
Huaguang Lu ◽  
Mahmoud Moussa Ismail ◽  
Owais Ahmed Khan ◽  
Yousef Al Hammad ◽  
Salah Haban Abdel Rhman ◽  
...  

Viruses ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1389 ◽  
Author(s):  
Sol Jeong ◽  
Dong-Hun Lee ◽  
Jung-Hoon Kwon ◽  
Yu-Jin Kim ◽  
Sun-Hak Lee ◽  
...  

In October 2020, a highly pathogenic avian influenza (HPAI) subtype H5N8 virus was identified from a fecal sample of a wild mandarin duck (Aix galericulata) in South Korea. We sequenced all eight genome segments of the virus, designated as A/Mandarin duck/Korea/K20-551-4/2020(H5N8), and conducted genetic characterization and comparative phylogenetic analysis to track its origin. Genome sequencing and phylogenetic analysis show that the hemagglutinin gene belongs to H5 clade 2.3.4.4 subgroup B. All genes share high levels of nucleotide identity with H5N8 HPAI viruses identified from Europe during early 2020. Enhanced active surveillance in wild and domestic birds is needed to monitor the introduction and spread of HPAI via wild birds and to inform the design of improved prevention and control strategies.


2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Dae-sung Yoo ◽  
Chun Byung Chul

Abstract Background Highly pathogenic avian influenza (HPAI), a zoonotic infectious disease, has been considered a severe threat to public health. The fundamental prevention and control strategy against HPAI includes minimizing the outbreaks of poultry holdings where the virus primarily spreads through animal trade and poultry production associated vehicle movement (PPVM). However, very few attempts have been made to elucidate the association between PPVM and HPAI transmission compared to studies on poultry trade. Therefore, our study aimed to elucidate the role of PPVM on HPAI transmission. Methods We performed network analysis using PPVM data based on a global positioning system (GPS), with phylogenetic information of the HPAI virus for reliable estimation. Moreover, the contribution of PPVM to HPAI infection was estimated by Bayesian inference. Results The network analysis revealed that the connection via PPVM between the same genetic group of infected premises (IPs) was more prevalent than that of different genotype IPs. Moreover, the similarity of farm poultry species and the overlapped integrators between inter-linked IPs was associated with potential transmission route formation. Additionally, the contribution of PPVM among phylogenetically clustered IPs was estimated to have 28.25% of HPAI infections in IPs on average. Conclusions HPAI control strategies including targeted movement restriction and standstill should be established against the HPAI transmission via PPVM. Key messages This is a solid and novel study depicting the need for combining epidemiological analysis with data regarding molecular epidemiology of pathogens.


2018 ◽  
Vol 14 (9) ◽  
pp. e1006439 ◽  
Author(s):  
Edward M. Hill ◽  
Thomas House ◽  
Madhur S. Dhingra ◽  
Wantanee Kalpravidh ◽  
Subhash Morzaria ◽  
...  

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Yao-Tsun Li ◽  
Chen-Chih Chen ◽  
Ai-Mei Chang ◽  
Day-Yu Chao ◽  
Gavin J D Smith

Abstract Highly pathogenic avian influenza (HPAI) A(H5) viruses belonging to clade 2.3.4.4c of the A/goose/Guangdong/1/96-like (Gs/GD) lineage caused severe global outbreaks in domestic birds from 2014 to 2015, that also represented the first incursions of Gs/GD viruses into Taiwan and the USA. However, few studies have investigated the circulation of clade 2.3.4.4c viruses after 2015. Here, we describe Gs/GD clade 2.3.4.4c and Mexican-like H5N2 viruses that were isolated in Taiwan during active surveillance conducted in chicken farms from February to March 2019. Phylogenetic analysis demonstrated two distinct genome constellations of the clade 2.3.4.4c H5 viruses, with the internal genes of one of the new genotypes closely related to a virus isolated from a pintail (Anas acuta) in Taiwan, providing the first direct evidence that migratory birds play a role in importing viruses into Taiwan. Our study also confirmed the co-circulation of Gs/GD clade 2.3.4.4c and Mexican-like H5 lineage viruses in Taiwan, presenting a rare case where Gs/GD viruses developed sustained transmission alongside another enzootic H5 lineage, raising the possibility that homosubtypic immunity may mask virus transmission, potentially frustrating detection, and the implementation of appropriate control measures. To eradicate H5 viruses from poultry in Taiwan, further studies on the effect of co-circulation in poultry of low pathogenic avian influenza and HPAI viruses are needed. Furthermore, only with continued surveillance efforts globally can we fully discern dispersal patterns and risk factors of virus transmission both to and within Taiwan.


Vaccine ◽  
2009 ◽  
Vol 27 (45) ◽  
pp. 6345-6352 ◽  
Author(s):  
Maria D. Van Kerkhove ◽  
Sirenda Vong ◽  
Javier Guitian ◽  
Davun Holl ◽  
Punam Mangtani ◽  
...  

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