ATOMIC FORCE MICROSCOPY OF THE ERYTHROCYTE IN VARIOUS SEVERITY OF OBSTRUCTIVE JAUNDICE (EXPERIMENTAL STUDY)

Author(s):  
R. A. Pakhomova ◽  
Yu. S. Vinnik ◽  
L. V. Kochetova ◽  
E. A. Voronova ◽  
Yu. S. Nagornov
2021 ◽  
Vol 91 (10) ◽  
pp. 1560
Author(s):  
В.М. Корнилов ◽  
А.Н. Лачинов ◽  
А.Р. Юсупов

The results of an experimental study of the local electrophysical properties of ultrathin polymer films by atomic force microscopy with a conducting probe are presented. It is established that visualization of current flow sites (conducting channels) is possible in areas from which the surface layer has been mechanically removed. The conducting channels in the current image have the form of individual points with a height corresponding to the locally flowing current. It is found that the location of the observed channels correlates well with the model of conductivity along the grain boundaries of the supramolecular structure of the polymer.


2017 ◽  
Vol 19 (9.1) ◽  
pp. 177-190
Author(s):  
Yu.S. Nagornov ◽  
I.V. Zhilyaev

The paper presents a model for the calculation of morphofunctional erythrocyte properties. The model represents the erythrocyte as a homogeneous elastic body with elastic depending on the distance to the center of symmetry of the erythrocyte. The data for modeling were taken from the experimental study, which were used by atomic force microscopy (measuring the elasticity of the membrane of erythrocytes and morphology) and the Coulter method. In the developed model, the elasticity of the membrane to change depending on the distance to the center within 1-1,6 kPa. The calculation of the elastic properties is made by two methods - finite element analysis and optimization methods. In the model the dependence of erythrocyte morphology on the membrane pressure was obtained. Pressure difference across the erythrocyte membrane varied in the range of 0,5-2 kPa.


Author(s):  
Cherry C. Chen ◽  
Shih-Ying Wu ◽  
John D. Finan ◽  
Barclay Morrison ◽  
Elisa E. Konofagou

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