scholarly journals Incidence of Methotrexate induced Posterior Reversible Encephalopathy Syndrome in Pediatric Cancer Patients; A Case Series from a Tertiary Care Hospital, Pakistan

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Mazhar S ◽  
Elahi E ◽  
Khan SA ◽  
Andleeb S
Keyword(s):  
Cancer Patients ◽  
Posterior Reversible Encephalopathy Syndrome ◽  
Pediatric Cancer ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Case Series ◽  
Care Hospital ◽  
Posterior Reversible Encephalopathy ◽  
Pediatric Cancer Patients ◽  
Reversible Encephalopathy

scholarly journals Clinico-radiological spectrum of obstetric patients with posterior reversible encephalopathy syndrome in a tertiary care hospital

2021 ◽  
Vol 9 (3) ◽  
pp. 701
Author(s):  
Neenu Alexander ◽  
C. Justin
Keyword(s):  
Posterior Reversible Encephalopathy Syndrome ◽  
South India ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Posterior Reversible Encephalopathy ◽  
Magnetic Imaging ◽  
Neuro Imaging ◽  
Reversible Encephalopathy ◽  
Visual Disturbances

Background: Posterior reversible encephalopathy syndrome (PRES) is a disorder that is not uncommon in pregnancy induced hypertension. We have studied the clinico radiological profile of such patients to understand history, symptomatology and neuro imaging findings of this entity.Methods: The present study included 20 patients of PRES among the inpatients of a tertiary care hospital in south India from January to March 2020.Results: Mean age 25.0 years. Most common symptoms included seizures and headache followed by vomiting, visual disturbances.9 patients (45%) had parieto-occipital signal changes on neuro imaging. Magnetic imaging resonance (MRI) (n=20) revealed involvement of atypical sites viz. frontal (30%), temporal (20%), cerebellum (20%), basal ganglia (20%), deep white matter (30%) and brainstem (10%).Diffusion restriction was seen in 40% patients.Conclusions: Atypical MRI presentations of PRES are common and there is a need to consider a strong possibility for the diagnosis of PRES.

scholarly journals Clinical spectrum of patients with posterior reversible encephalopathy syndrome

2020 ◽  
Vol 7 (10) ◽  
pp. 1537
Author(s):  
Sriramchandra Rahul Pulavarty ◽  
Nagabhushana Midathala
Keyword(s):  
Posterior Reversible Encephalopathy Syndrome ◽  
Tertiary Care ◽  
Severe Anaemia ◽  
Sudden Onset ◽  
Common Symptom ◽  
Care Hospital ◽  
Imaging Features ◽  
Posterior Reversible Encephalopathy ◽  
Altered Sensorium ◽  
Reversible Encephalopathy

Background: Posterior reversible encephalopathy syndrome is a neurological disorder which can present with sudden onset headache, visual disturbances, seizures and altered sensorium which is potentially reversible with early detection and treatment of the precipitating factor. The range of presentations is being constantly widened and this endeavour is a step towards understanding the wide array of presentation and primary etiology.Methods: This is a prospective observational study of 25 patients presenting to a tertiary care hospital with symptoms and imaging features suggestive of PRES. Thorough clinical examination and MRI brain were performed in all patients.Results: Out of the 25 patients, 18 (72%) were females and 7 (28%) were males. Most common symptom was headache (84%) followed by seizures (56%), nausea (40%), visual blurring (36%) and altered sensorium (20%). In patients presenting with seizure, 28.57% had recurrent seizures.The most common precipitating cause was postpartum state without hypertension (40%) followed by accelerated hypertension (28%), eclampsia (16%), chronic kidney disease (12%) and one patient of chronic severe anaemia had PRES following blood transfusion (4%). Most of the patients improved with no residual neurological deficit.Conclusions: Good neurological outcomes can be achieved by early diagnosis and appropriate imaging in patients with PRES. In pregnant and postpartum patients, PRES should be always considered even with normal blood pressure. Rapid correction of chronic severe anaemia is a rare but preventable cause of PRES.

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