scholarly journals Toxic effects of some acaricides on Aceria oleae (Nalepa, 1900) (Acari: Eriophyidae) and its predator Neoseiulus californicus (McGregor, 1954) (Acari: Phytoseiidae) under laboratory conditions

2021 ◽  
Vol 45 (4) ◽  
pp. 485-498
Author(s):  
Nabi Alper KUMRAL ◽  
Sultan ÇOBANOĞLU ◽  
Pınar HEPHIZLI GÖKSEL ◽  
Anıl AKSOY
Keyword(s):  
Toxic Effects ◽  
Neoseiulus Californicus ◽  
Laboratory Conditions

scholarly journals Effects of Apigenin and Apigenin- Loaded Nanogel on Induction of Apoptosis in Human Chronic Myeloid Leukemia Cells

2018 ◽  
Vol 7 ◽  
pp. e1008
Author(s):  
Mehrdad Hashemi ◽  
Nooshin Samadian
Keyword(s):  
Drug Delivery ◽  
Flow Cytometry ◽  
Chronic Myeloid Leukemia ◽  
Cell Line ◽  
K562 Cell ◽  
Myeloid Leukemia ◽  
Toxic Effects ◽  
Blue Staining ◽  
K562 Cell Line ◽  
Laboratory Conditions

Background: Diet plays an important role in cancer prevention. Apigenin, a flavonoid with thechemical formula C15H10O5, is abundantly present in vegetables. Vegetarian foods containing flavonoids are rich sources of bioactive compounds. Flavonoids have been utilized in herbal treatment. Nanogels are drug delivery systems based on polymers and are used in tissue engineering and for drug delivery. This study was conducted to compare the effects of apigenin and a nanodrug on the viability of the K562 cell line of chronic myeloid leukemia at different durations under laboratory conditions. Materials and Methods: Chitosan was first dissolved in 1% acetic acid, and  ethylene dichloride EDC and NHS were added to the solution. Then, the nanodrug was prepared by loading apigenin into stearate–chitosan nanogel (scs nanogel), and its physical and morphological characteristics were evaluated by TEM, DLS, and FTIR. Trypan blue staining, MTT assay, and flow cytometry were used to analyze the effects of various concentrations of apigenin and apigenin-loaded chitosan–stearate nanogel (APG–SCS) at 24, 48, and 72 h after they were applied to the K562 cell line. Results: The diameter of the nanodrug particles was measured using DLS and confirmed by TEM. The K562 cells treated with APG–SCS and with apigenin exhibited significant differences compared with the control (P < 0.05). Apoptosis was detected by flow cytometry. Conclusion: This study showed that the toxic effects of apigenin and the nanodrug improved with increasing concentrations and exposure durations compared to those in the control.The toxic effect of apigenin loaded into the stearate-chitosan nanogel was greater than apigenin, and the toxic effects of both materials were greater compared to the control under laboratory conditions.[GMJ.2018;7:e1008]

scholarly journals Bazı Bitki Ekstraktlarının Tribolium confusum Duv. (Coleoptera:Tenebrionidae) ve Rhyzopertha dominica F. (Coleoptera: Bostrichidae) Üzerindeki Kontakt Toksisitesi

2019 ◽  
Vol 7 (11) ◽  
pp. 1785
Author(s):  
Şeyda Şimşek ◽  
Mehtap Gürsoy ◽  
Seher Karaman Erkul
Keyword(s):  
Single Dose ◽  
Effect Study ◽  
Tribolium Confusum ◽  
Toxic Effects ◽  
Rhyzopertha Dominica ◽  
Contact Toxicity ◽  
Methanol Extracts ◽  
Laboratory Conditions

In this study, the toxic effects of methanol extracts obtained from, Reseda lutea L. (Resedaceae), Salvia absconditiflora Greuter & Burdet. (Lamiaceae), Thymus leucostomus Hausskn. & Velen. (Lamiaceae), Chorispora purpurascens (Banks & Sol.) Eig (Brassicaceae), Isatis floribunda Boiss. ex Bornm. (Brassicaceae) and Linum tenuifolium L. (Linaceae) plants were tested on Tribolium confusum Duv. (Col.: Tenebrionidae) and Rhyzopertha dominica F. (Col.: Bostrichidae) in laboratory conditions. The methanol extracts obtained from the plants were applied to the adults of the pests by micro-aplicator. As a result of the single dose (10% (w/v)) effect study, the highest contact toxicity against T. confusum (23.17%) and R. dominica (18.35%) showed the extract obtained from C. purpurascens plant.

Ultrastructure of the effect of T-514 obtained from Karwinskia humboldtiana on assembly and integrity of yeast's peroxisomes

1991 ◽  
Vol 49 ◽  
pp. 136-137
Author(s):  
J. Sepulveda-Saavedra ◽  
I. Vander-Klei ◽  
M. Venhuis ◽  
Y. Piñeyro-Lopez
Keyword(s):  
Culture Conditions ◽  
Toxic Effects ◽  
Candida Boidinii ◽  
Central Mexico ◽  
Poisonous Plant ◽  
Biological Behaviour ◽  
Enzyme Content ◽  
Fat Deposits ◽  
Yeast Model

Karwinskia humboldtiana is a poisonous plant that grows in semi desertic areas in north and central México. It produces several substances with different toxic effects. One of them designated T-514 damages severely the lung, kidney and liver, producing in the hepatoeyte large intracellular fat deposits and necrosis. Preliminary observations demonstrated that three is a decrease in the amount of peroxisomes in the hepatocytes of experimentally intoxicated rats and monkeys. To study the effect exerted by the T-514 on peroxisomes, a yeast model was selected, thus, three species: Saccha romices cerevisiae, Ilansenula polymorpha and Candida boidinii were used, because there is information concerning their peroxisome's morphology, enzyme content, biological behaviour under different culture conditions and biogenesis.

Some Conditions Necessary for Pinocytosis

1968 ◽  
Vol 26 ◽  
pp. 142-143
Author(s):  
M. W. Brightman
Keyword(s):  
Smooth Muscle ◽  
Cell Membrane ◽  
Toxic Effects ◽  
Cytological Evidence ◽  
Cell Processes

The cytological evidence for pinocytosis is the focal infolding of the cell membrane to form surface pits that eventually pinch off and move into the cytoplasm. This activity, which can be inhibited by oxidative and glycolytic poisons, is performed only by cell processes that are at least 300A wide. However, the interpretation of such toxic effects becomes equivocal if the membrane invaginations do not normally lead to the formation of migratory vesicles, as in some endothelia and in smooth muscle. The present study is an attempt to set forth some conditions under which pinocytosis, as distinct from the mere inclusion of material in surface invaginations, can take place.

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