scholarly journals Lung tuberculosis in a horse caused by Mycobacterium avium subsp. avium of serotype 2: a case report

2008 ◽  
Vol 53 (No. 2) ◽  
pp. 111-116 ◽  
Author(s):  
I. Pavlik ◽  
P. Jahn ◽  
M. Moravkova ◽  
L. Matlova ◽  
F. Treml ◽  
...  

Interstitial pneumonia (2/3 of the lungs were affected) and diffusely enlarged bronchial and mediastinal lymph nodes were diagnosed by gross examination of a dead 16-year-old mare. Based on histopathological examination and the detection of acid-fast rods after staining by the Ziehl-Neelsen technique, tuberculosis was suspected. <I>Mycobacterium avium</I> subsp. <I>avium</I> of serotype 2 and IS<I>901</I>+/IS<I>1245</I>+ genotype was isolated from the pulmonary lymphnode after five-week incubation at 37°C. Due to the fact that horses have a naturally high resistance to mycobacterial infections, the high age of the mare most likely contributed to the development of the disease.

2012 ◽  
Vol 01 (03) ◽  
pp. 136-140
Author(s):  
P Savithri

AbstractA case report of anomalous origin and branching pattern of right external carotid artery found during the dissection of human cadavers is reported here. Knowledge of anatomical variations of external carotid artery is especially important in head & neck surgeries. This knowledge is also important for radiologists in the image interpretation. In the case reported here, the right external carotid artery gave direct origin of one of dorsal lingual artery, two stylomastoid arteries, muscular artery and lymph nodal artery along with its normal eight branches. Generally the dorsal lingual arteries are two arising from lingual artery. Contrary to that, in this case the dorsal lingual arteries were found arising one from front of external carotid artery and other from lingual artery, and both these arteries communicated at 4mm beyond their origin. The two stylomastoid arteries arising directly from the front of external carotid artery 4mm above the facial artery were found arising with a gap of 2mm distance from one another. Muscular artery arose directly from the posterior aspect of external carotid artery opposite the anomalous dorsal lingual artery and descended downwards and forwards in its course giving small twigs to surrounding muscles . Lymph nodal artery arising just beside the muscular artery opposite to facial artery passed downwards and laterally and divided into two small twigs to supply a pair of lymph nodes. These lymph nodes are deep cervical nodes measuring about 5x5 mm in size hard in consistency on histopathological examination, found to be nonmalignant.


Haigan ◽  
2001 ◽  
Vol 41 (1) ◽  
pp. 73-78 ◽  
Author(s):  
Atsushi Morio ◽  
Hideaki Miyamoto ◽  
Hiroshi Izumi ◽  
Akio Yamazaki ◽  
Yasuyuki Hosoda

2020 ◽  
Vol 9 (2) ◽  
pp. 62-65
Author(s):  
Paweł Krawczyński ◽  
Wojciech Brzoznowski

Castleman disease is a rare lymphoproliferative disease occurs most often in lymph nodes located in the chest. The extra-nodal form concerns 25% of diagnosed cases of this disease entity. We present the case of Castelman disease localized in the parotid gland in a 15-year-old boy, confirmed by histopathological examination, clinically progressing as a right parotid gland tumor.


2021 ◽  
Vol 90 (2) ◽  
pp. 221-223
Author(s):  
Martin Levkut ◽  
Peter Major ◽  
Lucia Kottferová ◽  
Mikuláš Levkut

In this case report, lymphoblastic leukaemia is described in a five-year-old female guinea pig. Clinical examination revealed lymphadenopathy, mainly with increased size of the popliteal lymph nodes. Lymphoblast cells were determined haematologically. Postmortem findings were hepatomegaly and splenomegaly. Histopathological examination of liver, spleen and lymph nodes revealed tumour cells of lymphoblastic type. These cells showed considerable cellular pleomorphism. The protein markers CD3 and CD20 and paired box 5 (PAX5) transcription factor were traced immunohistochemically. Immunophenotypization using PAX5 showed nuclear positivity of this marker, but CD3 and CD20 (not interspecies cross-reactivity for guinea pig) demonstrated no positive reaction in the tumour cells. CD3-positive cells were found only in guinea pig tissue sections used as control. PAX5 in guinea pigs appears as a beneficial and preferred marker for B-cell derived tumours.


2014 ◽  
Vol 8 (5) ◽  
pp. 2221-2224 ◽  
Author(s):  
MUSTAPHA M. EL-HALABI ◽  
SAID A. CHAABAN ◽  
JOSEPH MEOUCHY ◽  
SETH PAGE ◽  
WILLIAM J. SALYERS

2019 ◽  
Vol 22 (1) ◽  
pp. 114-121
Author(s):  
O. O Alaka ◽  
T. A. Jarikre ◽  
B. N. Ogunro ◽  
Y. G. Gurumyen ◽  
A. C. Mark ◽  
...  

This case report describes for the first time pulmonary blastomycosis in a captive common eland (Taurotragus oryx). The animal has been in captivity for over 14 years and the clinical signs observed before death were non-specific. The carcass was examined grossly and histologically using special stains. There were yellowish, firm and gritty nodules of varying sizes (0.5–2 cm in diameter) on the pleura, in the lung, mediastinal lymph nodes and pericardium. The nodules showed pyogranulomatous inflammation and broad based budding yeast (PAS, Giemsa positive and ZN negative) consistent with Blastomyces dermatitidis. Regular screening of soil and environment including animals in captivity should be encouraged to avert possible spread of the mold in favourable conditions. Public awareness should be improved on fungal diseases.


2016 ◽  
Vol 42 (01) ◽  
pp. 35-39 ◽  
Author(s):  
Roh-Kyum Lee ◽  
Yu-Lun Tsai ◽  
Hui-Ju Wang ◽  
Cheng-Chung Lin ◽  
Shih-Chieh Chang ◽  
...  

A three-year-old female intact albino ferret was presented with clinical signs of panting, hyperpnea, weakness in all four limbs, loss of the swallowing reflex, lockjaw and sudden paleness of the oral mucosa and extremities. An abdominal mass was discovered during palpation. The patient died suddenly after clinical signs were observed. At necropsy, hemoperitoneum was noted in the abdominal cavity and a [Formula: see text][Formula: see text]cm dark red moruloid mass was found in the mesentery of the ileum. Histopathological examination of the mass revealed multiple cavernous structures with significant blood accumulation. Oval to polygonal neoplastic cells with frequent mitotic figures were also noted. Furthermore, neoplastic cells were positively stained with antibodies of CD34 and Factor VIII, and had metastasized to the mesentery lymph nodes. The definitive diagnosis was visceral hemangiosarcoma in a ferret.


2021 ◽  
Author(s):  
Tomohito Okubo ◽  
Nariyasu Nakashima ◽  
Yoshimasa Tokunaga ◽  
Nobuyuki Kita ◽  
Hiroyuki Nakamura ◽  
...  

Abstract Background: Immunoglobulin G4-related disease (IgG4-RD) is characterized by the formation of inflammatory lesions with fibrosis and infiltration of IgG4-positive plasma cells and lymphocytes in various organs of the body. Since the first report of IgG4-related autoimmune pancreatitis, IgG4-RD affecting various organs has been reported; however, there are still only a few reports of IgG4-related lung disease (IgG4-RLD). In this report, we describe a case of IgG4-RLD with recurrent pulmonary lesions during steroid therapy that were difficult to differentiate from malignancy.Case presentation: A 61-year-old man was referred to our hospital after an abnormal chest shadow on X-ray was noted during his visit to his previous doctor for asthma treatment. Chest computed tomography (CT) revealed a middle lobe hilar mass with irregular margins and swelling of the right hilar and mediastinal lymph nodes. 18F-fluorodeoxyglucose-positron emission tomography revealed a mass lesion with a maximum diameter of 5.5 cm, maximum standardized uptake value (SUVmax) of 11.0, and areas with high SUV in the hilar and mediastinal lymph nodes. We suspected lung cancer or malignant lymphoma and performed a thoracoscopic lung biopsy to confirm the diagnosis. A total of five tumor sites and an enlarged lymph node (LN#10) were biopsied; histopathological examination revealed no malignant findings, and IgG4-RLD was diagnosed. One month after treatment with prednisolone (PSL), the tumor had shrunk, but a CT scan during the third month of PSL treatment revealed multiple nodular shadows in both lungs. Considering the possibility of malignant complications and multiple lung metastases, we performed thoracoscopic partial lung resection of the new left lung nodules to determine the treatment strategy. Histopathological examination revealed no malignant findings in any of the lesions, and the patient was diagnosed with IgG4-RLD refractory to PSL monotherapy. We are considering the combination of azathioprine and PSL as future treatment.Conclusions: IgG4-RLD refractory to PSL monotherapy showed changes from a solitary large mass (pseudotumor) to multiple nodules on chest CT. It was difficult to distinguish malignancy from IgG4-RLD based on imaging tests and blood samples alone, and performing thoracoscopic lung biopsies and partial lung resection were useful in determining the diagnosis and treatment plan.


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