The Co-Analgesic Efficacy of Preoperative Single Dose Gabapentin after Surgical Removal of Lower Third Molars

2022 ◽  
Vol 9 (1) ◽  
pp. 1-7
Author(s):  
Piotr Wichary
2016 ◽  
Vol 7 (2) ◽  
pp. 38-41 ◽  
Author(s):  
Shruthi Rangaswamy ◽  
Kedarnath N Sheshappa ◽  
Rohit Srikanthan

ABSTRACT Introduction Preemptive analgesia is an evolving concept where therapeutic intervention be made prior to the onset of pain. This study was done to evaluate the effectiveness of diclofenac sodium 100 mg as preemptive analgesic administered 1 hour before removal of impacted third molars using split mouth study model. Materials and methods A randomized placebo control study was done on 30 patients requiring bilateral impacted tooth removal. Patients were administered 100 mg of diclofenac sodium and placebo 1 hour prior to surgery at different appointments. Patients were assessed for intraoperative pain and postoperative pain with visual analog scale on 1st, 2nd, and 3rd postoperative days. Results Statistical difference was found in pain experience during 1st postoperative day (p = 0.0153). Patients after receiving diclofenac sodium 100 mg experienced less pain compared to placebo side. There was no difference found in pain experience between the study and control groups on subsequent postoperative days and overall pain experience. Conclusion Better management of pain improves quality of life after procedure. Thus, preemptive analgesia may be beneficial in reducing pain intensity. Larger sample blinded studies may prove efficiency of preemptive analgesia. How to cite this article Rangaswamy S, Sheshappa KN, Srikanthan R. Preemptive Analgesic Efficacy of Diclofenac Sodium for Surgical Removal of Impacted Third Molars. J Health Sci Res 2016;7(2):38-41.


2013 ◽  
Vol 12 (4) ◽  
pp. 382-386
Author(s):  
Vikrant Dilip Sane ◽  
Kiran Shrikrishna Gadre ◽  
Sanjay Chandan ◽  
Shandilya Ramanojam ◽  
Vikram Singh ◽  
...  

2015 ◽  
Vol 12 (1) ◽  
pp. 4-8 ◽  
Author(s):  
N Vyas ◽  
S Agarwal ◽  
N Shah ◽  
D Patel ◽  
P Aapaliya

Background Lower impacted third molar surgical extraction usually causes post-surgical sequelae like pain, trismus and swelling as a result of postoperative inflammatory response.Objective The aim of this study was to evaluate and compare the efficacy of single dose 40-mg (1cc) of methylprednisolone acetate, injected into the masseter muscle, preoperatively one hour before the surgery or post-operatively, immediately following the surgical removal of impacted lower third molars, in controlling most common postoperative sequelae, i.e. trismus, pain and swelling of facial soft tissue.Methods A randomized control study was done of 60 patients. Each patient was categorized in two groups, group I and group II, according to the time of receiving methylprednisolone acetate. Group I was injected 40mg of methylprednisolone acetate into the masseter muscle via the intrabuccal approach, one hour before the surgery. Group II was injected 40mg of methylprednisolone acetate into the masseter muscle via the intrabuccal approach, immediately after suturing of the surgical wound. The washout period was one month after the first operation. Evaluation were made of postoperative pain, trismus and swelling. The numeric pain scale (NPS) was used for pain assessment.Results When the patients were administered methylprednisolone acetate preoperatively, showed superior results in terms of oral aperture, pain and all the facial swelling parameters, with statistically significant differences versus the postoperatively administered methylprednisolone acetate (p < 0.05).Conclusions A single dose of 40 mg (1cc) methylprednisolone acetate injected into the masseter muscle preoperatively is more effective in reducing pain, trismus and swelling, when compared to that administered postoperatively.Kathmandu University Medical Journal Vol.12(1) 2014: 4-8


2020 ◽  
Vol 11 (4) ◽  
pp. 6188-6195
Author(s):  
Jones Jayabalan ◽  
Muthusekhar M R ◽  
Senthil Murugan P

The study aimed to compare the analgesic efficacy of 100 mg and 20 mg as a analgesic for preventing post-operative pain after third molar surgery. Fifty patients with impacted mandibular third molars who required surgical removal were included in the study. These patients were divided into two groups randomly. One group consisted of patients receiving 100 mg as a analgesic, and the other group consisted of patients receiving 20 mg as a analgesic 1 hour before the procedure. The study findings show both the drugs were equally effective in managing post-operative pain following third molar surgery. On statistical analysis, there was no significant difference in pain experience among both groups A and B in post-operative period who underwent surgery. However, the study observes a highly significant difference in both the groups in terms of pain intensity scores at different times. Results show that there was a significant difference before, 3rd day and 5th day; Further study shows that the effectiveness of the drug was not confirmed in 24 hours to 3 days. It was observed both the groups shows a significant difference in on the 5thand 3rd day. This comparative research of pain intensity shows after analgesia with and in of third molars, a pronounced effect in the group treated with 20mg was seen. Still, there was no statistically significant difference noted in VAS before and 5th day of both groups.


Author(s):  
Josefine Cederhag ◽  
Nina Lundegren ◽  
Per Alstergren ◽  
Xie-Qi Shi ◽  
Kristina Hellén-Halme

Abstract Objectives The aim was to evaluate the characteristics of the mandibular third molars, especially in relation to the inferior alveolar nerve. Further aims were to investigate incidental findings in panoramic radiographs in an adult population, and to investigate image quality related to patient positioning. Materials and Methods From a previous study with 451 randomly selected adult participants who lived in Sweden, 442 panoramic radiographs from four dental public health clinics were used. The third molars’ characteristics and relation to inferior alveolar nerve were evaluated. Incidental findings and patient positioning were recorded. Statistical Analysis Frequency analysis was used to investigate the occurrence of all findings and their possible interconnections. Whether the patients’ age or gender had an impact or not was also analyzed. Results The third molars were erupted in vertical position among 73% regardless of age. When retained or semi-retained, they were most commonly in mesioangular positions. The inferior alveolar nerve was located inferior to the roots in 52%, whereas an overlapped position was most common if the third molar was retained (90%), semi-retained (83%) or the age was less than 30 years (66%). Common incidental findings were apical radiolucencies, idiopathic osteosclerosis, and tooth fragments. Suboptimal patient positioning was found in one-third of the radiographs. Conclusions Panoramic radiography is a useful method to evaluate third molar prior to surgical removal and may be the only image required. Most incidental findings on panoramic radiographs does not seem to require any further odontological management.


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