A Study on the Effects of Climate Change Factors on the Adverse Drug Event (ADE) Reports Focusing on Diarrhea and Respiratory Diseases

Yakhak Hoeji ◽  
2021 ◽  
Vol 65 (6) ◽  
pp. 481-486
Author(s):  
Sunghyun Lee ◽  
Bowon Jang ◽  
YeunKum Lee
Keyword(s):  
Climate Change ◽  
Adverse Drug Event ◽  
Respiratory Diseases ◽  
Drug Event ◽  
Change Factors

scholarly journals Using ActionADE to create information continuity to reduce re-exposures to harmful medications: study protocol for a randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jeffrey P. Hau ◽  
Penelope M. A. Brasher ◽  
Amber Cragg ◽  
Serena Small ◽  
Maeve Wickham ◽  
...  
Keyword(s):  
Health Information ◽  
Adverse Drug Event ◽  
Primary Outcome ◽  
Adverse Drug Events ◽  
Primary Objective ◽  
Drug Event ◽  
Controlled Trials ◽  
Drug Reactions ◽  
Main Trial ◽  
Randomized Controlled

Abstract Background Repeat exposures to culprit medications are a common cause of preventable adverse drug events. Health information technologies have the potential to reduce repeat adverse drug events by improving information continuity. However, they rarely interoperate to ensure providers can view adverse drug events documented in other systems. We designed ActionADE to enable rapid documentation of adverse drug events and communication of standardized information across health sectors by integrating with legacy systems. We will leverage ActionADE’s implementation to conduct two parallel, randomized trials: patients with adverse drug reactions in the main trial and those diagnosed with non-adherence in a secondary trial. Primary objective of the main trial is to evaluate the effects of providing information continuity about adverse drug reactions on culprit medication re-dispensations over 12 months. Primary objective of the secondary trial is to evaluate the effect of providing information continuity on adherence over 12 months. Methods We will conduct two parallel group, triple-blind randomized controlled trials in participating hospitals in British Columbia, Canada. We will enroll adults presenting to hospital with an adverse drug event to prescribed outpatient medication. Clinicians will document the adverse drug event in ActionADE. The software will use an algorithm to determine patient eligibility and allocate eligible patients to experimental or control. In the experimental arm, ActionADE will transmit information to PharmaNet, where adverse drug event information will be displayed in community pharmacies when re-dispensations are attempted. In the control arm, ActionADE will retain information in the local record. We will enroll 3600 adults with an adverse drug reaction into the main trial. The main trial’s primary outcome is re-dispensation of a culprit or same-class medication within 12 months; the secondary trial’s primary outcome will be adherence to culprit medication. Secondary outcomes include health services utilization and mortality. Discussion These studies have the potential to guide policy decisions and investments needed to drive health information technology integrations to prevent repeat adverse drug events. We present an example of how a health information technology implementation can be leveraged to conduct pragmatic randomized controlled trials. Trial registration ClinicalTrials.gov NCT04568668, NCT04574648. Registered on 1 October 2020.

Inter-rater Reliability of a Classification System for Hospital Adverse Drug Event Reports

2007 ◽  
Vol 83 (3) ◽  
pp. 485-488 ◽  
Author(s):  
K Haynes ◽  
S Hennessy ◽  
KH Morales ◽  
GA Gibson ◽  
C Barnhart ◽  
...  
Keyword(s):  
Adverse Drug Event ◽  
Classification System ◽  
Drug Event ◽  
Rater Reliability

scholarly journals Adverse Drug Event Detection in Pediatric Oncology and Hematology Patients: Using Medication Triggers to Identify Patient Harm in a Specialized Pediatric Patient Population

2014 ◽  
Vol 165 (3) ◽  
pp. 447-452.e4 ◽  
Author(s):  
Rosemary J. Call ◽  
Jonathan D. Burlison ◽  
Jennifer J. Robertson ◽  
Jeffrey R. Scott ◽  
Donald K. Baker ◽  
...  
Keyword(s):  
Pediatric Patient ◽  
Pediatric Oncology ◽  
Adverse Drug Event ◽  
Event Detection ◽  
Patient Population ◽  
Drug Event ◽  
Patient Harm ◽  
Pediatric Patient Population

scholarly journals Analysis of factors associated with hiccups based on the Japanese Adverse Drug Event Report database

PLoS ONE ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. e0172057 ◽  
Author(s):  
Ryuichiro Hosoya ◽  
Yoshihiro Uesawa ◽  
Reiko Ishii-Nozawa ◽  
Hajime Kagaya
Keyword(s):  
Adverse Drug Event ◽  
Drug Event ◽  
Event Report ◽  
Factors Associated
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