A rare case of osseous metaplasia in anaplastic thyroid cancer

Anaplastic thyroid cancer is the most advanced and aggressive thyroid cancer. It is very rare and isfound in less than 2% of patients with thyroid cancer. It most commonly occurs in people over theage of 60 years. It is usually diagnosed at later stages when the disease has already spread tosurrounding structures or has grown large enough to compress the trachea or esophagus causingpressure symptoms. The patient here, a 75-year-old female, presented with a large swelling in thefront of the neck in euthyroid status which was diagnosed as anaplastic thyroid cancer and wasmanaged surgically and the surgical specimen was sent for histopathological examination. Thepresence of osseous metaplasia with mature bone formation in anaplastic thyroid carcinoma is a rareentity and has been discussed in this case report.

Download Full-text

Metastatic Papillary Thyroid Carcinoma Arising in a Neglected Goiter: A Case Report

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2020.4232 ◽

2020 ◽

Vol 8 (C) ◽

pp. 55-59

Author(s):

Mohd Zulhilmie Mohd Nasir ◽

Alan Basil Peter ◽

Awla Mohd Azraai ◽

Khasnur Abd Malek

Keyword(s):

Thyroid Cancer ◽

Case Report ◽

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Lung Metastases ◽

Histopathological Examination ◽

Papillary Thyroid ◽

Surgical Specimen ◽

Ablation Therapy ◽

Diffuse Goiter

BACKGROUND: Periodical clinical surveillance for early thyroid cancer detection among patients with diffuse goiter is a common scenario managed in the primary care setting. However, clinical palpation alone is neither sensitive nor specific in detecting the presence of nodules within a goiter. Hence, further investigation with ultrasound is key to effective surveillance for early detection of thyroid cancer. CASE REPORT: We present a case of a stable diffuse goiter in a 51-year-old woman diagnosed 30 years ago who refused further imaging investigation. Based solely on clinical palpation, the presence of nodules within the goiter was missed. This resulted in transformation into papillary thyroid carcinoma with lung metastases. She presented with progressive hoarseness of voice and cough for 3 months. An ultrasound of the thyroid gland revealed a large heterogeneous nodule in the left lower pole with coarse calcification and internal vascularity. Further imaging with contrast-enhanced computed tomography of the neck and thorax revealed an enhancing nodule in the left thyroid lobe which extends inferiorly to the left retroclavicular region which compresses the trachea causing narrowing of its lumen at T1 and T2 vertebral levels. There were multiple lung nodules in both lungs suggestive of metastases. CONCLUSION: A total thyroidectomy followed by radioactive iodine thyroid ablation therapy was performed. The histopathological examination revealed the surgical specimen to be papillary thyroid carcinoma.

Download Full-text

Solitary Trichoepithelioma of Nose: A Rare Case Report and Review of Literature

International Journal of Head and Neck Surgery ◽

10.5005/jp-journals-10001-1237 ◽

2015 ◽

Vol 6 (3) ◽

pp. 115-117

Author(s):

Sachin Lal Shilpakar ◽

Bivek Aryal ◽

Shyam Thapa Chettri ◽

Apar Pokharel ◽

Deepak Paudel

Keyword(s):

Case Report ◽

Rare Case ◽

Histopathological Examination ◽

Hair Follicles ◽

Review Of Literature ◽

Solitary Lesion ◽

Biological Potential ◽

Rare Case Report ◽

The Face ◽

Head Neck

ABSTRACT The trichoepithelioma is a benign cutaneous neoplasm which is derived from hair follicles. It is common in the face, but there are only three reports of the solitary occurrence on the nose. It is often not recognized because of its rarity, controversial classification, origin and biological potential. The objective of this paper is to present a case of solitary trichoepithelioma on the nose, histopathological examination and treatment. It should be considered as a differential diagnosis of a solitary lesion of nose which is confused with basal cell carcinoma. The confirmation by histopathological examination is essential. How to cite this article Sah BP, Shilpakar SL, Aryal B, Chettri ST, Pokharel A, Mishra S, Paudel D. Solitary Trichoepithelioma of Nose: A Rare Case Report and Review of Literature. Int J Head Neck Surg 2015;6(3):115-117.

Download Full-text

A Rare Case of Vulvar and Umbilical Endometriosis in a Single Patient: A Case Report

Austin Journal of Dermatology ◽

10.26420/austinjdermatolog.2020.1090 ◽

2020 ◽

Vol 7 (1) ◽

Author(s):

Pathiraja PDM ◽

◽

Ranaraja SK ◽

Keyword(s):

Case Report ◽

Rare Case ◽

Histopathological Examination ◽

Single Patient ◽

Benign Disorder ◽

Ectopic Endometrium ◽

Umbilical Endometriosis

Endometriosis is a benign disorder and characterized by ectopic endometrium like tissues outside the uterus. We report a case of a 31 year-old woman referred to our clinic due to complaints of a vulvar and umbilical mass and periodic swelling with pain of the mass at the time of menstruation. The cyst was removed totally. Histopathological examination showed findings compatible with endometriosis in both. We have treated them with suppressive treatment with Depot Medroxy Progesterone Acetate (DMPA) and after six months patient was completely asymptomatic.

Download Full-text

Teratoma of larynx: case report

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20213909 ◽

2021 ◽

Vol 7 (10) ◽

pp. 1700

Author(s):

Rakesh Srivastava ◽

Vini Tandon

Keyword(s):

Carbon Dioxide ◽

Case Report ◽

Germ Cells ◽

Carbon Dioxide Laser ◽

Rare Case ◽

Histopathological Examination ◽

Flexible Laryngoscopy ◽

First Case ◽

Congenital Teratoma

<p class="abstract">Teratomas are embryonal neoplasm arises from totipotent germ cells. They are having tissues from all the three blastodermic layers. There are various locations of congenital teratoma. Naso-oropharyngeal site teratoma are either sessile or pedunculated. We describe a rare case of laryngeal teratoma in a five years old patient presented with change in voice and breathing difficulty. On flexible laryngoscopy, it appeared like supraglottic cyst but on CT scan it was confirmed as teratoma. Pre-operative tracheostomy and transoral carbon dioxide laser assisted excision done. Histopathological examination showed osteoid trabeculae, chondroid tissue with loose myxoid islands and adipose tissue. No recurrence of tumor on 18 months follow-up. This is the first case report of pediatric larynx teratoma reported in present century.</p>

Download Full-text

Pilomatricoma with florid osseous metaplasia: a rare case report

Menoufia Medical Journal ◽

10.4103/1110-2098.165825 ◽

2015 ◽

Vol 0 (0) ◽

pp. 0

Author(s):

Banyameen Iqbal ◽

Atul Jain ◽

Komal Sawaimul ◽

Tushar Kambale

Keyword(s):

Case Report ◽

Rare Case ◽

Osseous Metaplasia ◽

Rare Case Report

Download Full-text

Cerebral Coenurosis Masquerading as Malignancy: A Rare Case Report from India

Journal of Neurosciences in Rural Practice ◽

10.4103/jnrp.jnrp_296_18 ◽

2019 ◽

Vol 10 (02) ◽

pp. 367-370

Author(s):

Shamila Mohamed Ali ◽

P. Somashekara Reddy ◽

S. Venugopal ◽

Manmeet Chhabra ◽

Anita Mahadevan

Keyword(s):

Case Report ◽

Characteristic Feature ◽

Rare Case ◽

Histopathological Examination ◽

Surgical Excision ◽

Hydatid Cysts ◽

The Third ◽

Rare Case Report ◽

Cerebral Coenurosis ◽

Cuticular Layer

ABSTRACTHuman coenurosis is a rare zoonotic disease caused by the larvae of Tinea multiceps seen in sheep-rearing countries. We report the case of a 63-year-old male who was referred to our hospital with a working diagnosis of skull base chondrosarcoma. Histopathological examination after surgical excision revealed characteristic feature of coenurus with multiple scolices invaginating from the outer cuticular layer. Coenuri are often mistaken for giant cysticercal cysts and hydatid cysts. Despite its wide prevalence in cattle, only two cases of human coenurosis are reported from India till date. We report the third case from India.

Download Full-text

Thyroid Carcinoma with Pituitary Metastases: 2 Case Reports and Literature Review

Case Reports in Endocrinology ◽

10.1155/2015/252157 ◽

2015 ◽

Vol 2015 ◽

pp. 1-7 ◽

Cited By ~ 4

Author(s):

Weiying Lim ◽

Dawn Shaoting Lim ◽

Chiaw Ling Chng ◽

Adoree Yiying Lim

Keyword(s):

Thyroid Cancer ◽

Thyroid Carcinoma ◽

Radioiodine Therapy ◽

Follicular Thyroid Carcinoma ◽

Case Reports ◽

Anaplastic Thyroid Cancer ◽

Anaplastic Thyroid Carcinoma ◽

Pituitary Metastases ◽

History Of ◽

Loss Of Appetite

We present 2 patients with pituitary metastases from thyroid carcinoma—the first from anaplastic thyroid carcinoma and the second from follicular thyroid carcinoma. The first patient, a 50-year-old lady, presented with 2-week history of hoarseness of voice, dysphagia, dyspnoea, and neck swelling. Imaging revealed metastatic thyroid cancer to lymph nodes and bone. Histology from surgery confirmed anaplastic thyroid cancer. She was found to have pituitary metastases postoperatively when she presented with nonvertiginous dizziness. She subsequently underwent radiotherapy and radioiodine treatment but passed away from complications. The second patient, a 65-year-old lady, presented with loss of appetite and weight with increased goitre size and dyspnoea. Surgery was performed in view of compressive symptoms and histology confirmed follicular thyroid carcinoma. Imaging revealed metastases to bone, lung, and pituitary. She also had panhypopituitarism with hyperprolactinemia and diabetes insipidus. She received radioiodine therapy but eventually passed away from complications.

Download Full-text

Rare Case Report Of Mesenteric Fibromatosis

Polish Journal of Surgery ◽

10.1515/pjs-2015-0090 ◽

2015 ◽

Vol 87 (9) ◽

Author(s):

Radhika Vidyasagar ◽

Sudarshan ◽

Sreedhar ◽

Subramanya ◽

Vidya Bhat

Keyword(s):

Case Report ◽

Rare Case ◽

Histopathological Examination ◽

Mesenteric Tumor ◽

Mesenteric Fibromatosis ◽

Rare Case Report

AbstractMesenteric fibromatosis is a part of the clinical-pathologic spectrum of deep fibromatoses. We report this rare case of primary mesenteric tumor that was diagnosed to be a mesenteric fibromatosis on histopathological examination.In majority of patients it may remain asymptomatic and the management of these tumors depends on histopathological examination. Postoperatively, patient was well and subsequent follow up showed normal recovery.

Download Full-text

A rare case of perineal hamartoma associated with cryptorchidism and imperforate anus: case report

Einstein (São Paulo) ◽

10.1590/s1679-45082014rc2746 ◽

2014 ◽

Vol 12 (2) ◽

pp. 234-236

Author(s):

Kleiton Gabriel Ribeiro Yamaçake ◽

Amilcar Martins Giron ◽

Uenis Tannuri ◽

Miguel Srougi

Keyword(s):

Case Report ◽

Physical Examination ◽

Imperforate Anus ◽

Rare Case ◽

Coloanal Anastomosis ◽

Histopathological Examination ◽

Congenital Clubfoot ◽

Anorectal Anomaly ◽

Male Neonate ◽

Nonpalpable Testis

A full-term male neonate with anorectal anomaly and external perineal anomalies was referred to our service. Physical examination showed an epithelized perineal mass with cutaneous orifices, which had urine fistulization, hipotrofic perineal musculature, bilateral congenital clubfoot, hipospadic urethra, criptorquidy bilateral with nonpalpable testis and imperforate anus. A colostomy was constructed immediately after birth. The child underwent excision of perineal mass, bilateral orchidopexy, Duplay neourethroplasty and coloanal anastomosis at 3 months of age. The histopathological examination of the perineal mass revealed a hamartoma.

Download Full-text