scholarly journals Frequency of Diagnosed Gastrointestinal & Liver Diseases in Paediatric out Patient Department at a Tertiary Care Hospital of Karachi, Pakistan

2016 ◽  
Vol 5 (1) ◽  
pp. 1938-1940
Author(s):  
Sina Aziz ◽  
◽  
Ahmad Faraz ◽  
Shafaq Shahid
2021 ◽  
pp. 165-167
Author(s):  
Kumkum Sarkar ◽  
Rupak Chatterjee ◽  
Sumanta Sinha ◽  
Netai Pramanik

Background and objectives- Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide, with majority of the patients being asymptomatic and when they present to clinicians, they have already advanced liver disease in form of cirrhosis or hepatocellular carcinoma. Data from developing countries on this evolving global health problem are sparse. Hence this study was planned with the aim to determine the HCV genotypes prevalant in patients attending a tertiary care hospital with their clinical prole. Materials and Methods- Detailed history taking and clinical examination were done of consecutive 30 patients who attended out-patient department or admitted at in- patient department of Tropical Medicine with chronic hepatitis C. Laboratory investigations like LFT, viral serology (HBsAg, AntiHCV, HIV), prothrombin time, ultrasonography of upper abdomen, HCV- RNA Quantative assay with genotyping were done. Data were collected and then analysed using standard statistical methods. Result- Of proposed 30 sample size, complete data could be collected of 28 patients and accordingly, analysis was done. Of the 28 HCV seroreactive individuals, majority (20) were males. The mode of transmission was unknown in 19 patients, blood transfusion in 5 patients who were thalassemic and hemodialysis in remaining 4 patients. Most of the patients (18/28) were asymptomatic even if their viral load was high. Most common presenting symptom was dyspepsia. LFT showed signicant transaminitis in 50% of the patients. Of the 28 seroreactive patients, 15 (53.57%) were HCV RNA positive based on RT-PCR. HCV rNA was below detectable level in 13 patients. HCV genotype 3 was the predominant genotype found in 11 individuals followed by genotype 1 found in 3 and genotype 2 was seen in one individual. Conclusion- Community screening specially among high risk individuals is needed for early diagnosis and prompt treatment of chronic hepatitis C to prevent its several complications and also to prevent community spread.


Author(s):  
Shaikh Ubedulla S. I. D ◽  
Niloofar V.

Background: Geriatrics tend to be the largest consumers of prescribed drugs exposing them to various drug interactions and adverse drug reactions. Present study is an attempt to assess the drug utilization pattern of psychotropic drugs among the geriatrics in psychiatry out-patient department (OPD) of a tertiary care hospital in Kerala.Methods: Prescriptions of patients diagnosed with psychiatric illness and being prescribed at least one psychotropic drug were collected. Prescriptions of male and female patients of age more than 60 years were sorted and analysed separately according to WHO core prescribing indicators.Results: 18% prescriptions were of geriatric population. Depressive disorders (38.89%) were the most common psychiatric disorder encountered. Out of 291 drugs prescribed in geriatrics, 237(81.44%) drugs were psychotropic drugs. Among the total psychotropic drugs prescribed, antipsychotics (39.24%) were the most commonly prescribed class of drugs. Average number of psychotropic drugs per prescription was 2.19, drugs prescribed by generic name were 2.06% and the drugs prescribed from NLEM (2015) were 41.77%. 86.11% of prescriptions contained more than one drug and 33.33% of prescriptions contained FDCs.Conclusions: Prescription analysis using WHO prescribing indicators showed some deviations from the standard which can be improved. A trend of polypharmacy was noted in this study. Prescribing using generic name and prescribing from NLEM was low as compared to the other reference studies. Proper strategies taken to overcome the inadequacies pointed out by this study can ensure the rational use of medicines.


Author(s):  
Nisha Gupta ◽  
Rekha Sharma ◽  
Rukma L. Sharma

<p><strong>Background:</strong> Alopecia areata is a condition that is characterized by a well-defined round or oval patches of non-scaring hair loss in scalp or any hairy area of the body. Alopecia areata has become a major health problem faced by people all over the world. This research was done to ascertain the prevalence of alopecia areata in different age group and to study its association with autoimmune diseases and systemic illnesses.</p><p><strong>Methods:</strong> The present hospital based descriptive study includes 52 alopecia areata patients attending dermatology out-patient department.</p><p><strong>Results:</strong> It was seen that the disease can occur at any age group mostly affecting those between 21-40 years. The age of presentation varied from 14 to 48 years with male preponderance. It was found that arthritis was associated in 30.7%, ANA was positive in 7.7% and 12% had hypothyroidism. Eosinophilia was found in 34.6% and 7.7% had asthma among then.</p><p><strong>Conclusions:</strong> Our study shows that it could be associated with autoimmunity, thyroid abnormality, atopy and inflammation.</p>


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