PRODUCTION OF ANTI-MALARIAL AND ANTI-MIGRAINE DRUGS IN TISSUE CULTURE OF ARTEMISIA ANNUA AND TANACETUM PARTHENIUM

1993 ◽  
pp. 269-276 ◽  
Author(s):  
G.D. Brown
1999 ◽  
Vol 64 (7-8) ◽  
pp. 397-442 ◽  
Author(s):  
Slobodan Milosavljevic ◽  
Vanja Bulatovic ◽  
Milutin Stefanovic

1. Introduction 2. Results 3. Asteraceae 3.1. Genus Artemisia L. 3.1.1. Artemisia annua L. 3.1.2. Artemisia vulgaris L. 3.1.3. Artemisia absinthium L. (warmwood) 3.1.4. Artemisia scoparia W. et K. 3.1.5. Artemisia camprestris L. 3.2. Genus Ambrosia L. 3.2.1. Ambrosia artemisiifolia L. (the common rag weed) 3.3. Genus Tanacetum L. ( syn. Chrysanthemum L.) 3.3.1. Tanacetum parthenium L. (feverfew) 3.3.2. Tanacetum serotinum L. 3.3.3. Tanacetum vulgare L. (tansy) 3.3.4. Tanacetum macrophyllum Willd. 3.3.5. Tanacetum corymbosum L. 3.4. Genus Telekia Baumg. 3.4.1. Telekia speciosa (Schreb.) Baumg. 3.5. Genus Inula L. 3.5.1. Inula helenium L. 3.5.2. Inula spiraeifolia L. 3.6. Genus Eupatorium L. 3.6.1. Eupatorium cannabinum L. 3.7. Genus Achillea L. 3.7.1. Achillea abrotanoides Vis. 3.7.2. Achillea millefolium subsp. pannonica 3.7.3. Achillea crithmifolia W. et K. 3.7.4. Achillea clypeolata Sibth. et Sm. 3.7.5. Achillea serbica Nyman 3.7.6. Achillea depressa Janka 3.8. Genus Anthemis L. 3.8.1. Anthemis carpatica Willd. 3.8.2. Anthemis cretica L. subsp. cretica 3.9. Genus Centaurea L. 3.9.1. Centaurea derventana Vis. et Pan~. 3.9.2. Centaurea kosaninii Hayek 3.9.3. Centaurea solstitialis L. 4. Apiaceae 4.1. Genus Laserpitium L. 4.1.1. Laserpitium siler L. 4.1.2. Laserpitium marginatum L. 4.1.3. Laserpitium latifolium L. 4.1.4. Laserpitium alpinum W. K. 4.2. Genus Angelica L. 4.2.1. Angelica silvestris L. 4.3. Genus Peucedanum L. 4.3.1. Peucedanum austriacum (Jacq.) Koch


2020 ◽  
Vol 30 (1) ◽  
pp. 97-106
Author(s):  
Ely Zayova ◽  
Trendafil Nedev ◽  
Detelina Petrova ◽  
Miroslava Zhiponova ◽  
Venеta Kapchina ◽  
...  

Artemisia annua L. axenic plants were used to induce callogeneisis for production of phenolics and plant regeneration. Up to 95% callogenesis from leaf and stem explants on MS supplemented with 2.0 mg/l NAA or 2,4-D + 0.2 mg/l BAP (MSC1 and MSC2) was observed. Lower callus frequency but with improved embryogenic potential was observed upon subculture on medium with reduced auxin and increased BAP concentration (0.5 mg/l NAA or 2,4-D + 0.5 mg/l BAP) (MSC3 and MSC4). The leafinduced callus on NAA/BAP (MSC3) showed best antioxidant potential. Induced shoot regeneration occurred upon high concentration BAP combined with NAA rather than with 2,4-D (0.25 mg/l NAA or 2,4-D + 1.0 mg/l BAP, MSR 1 and MSR2, respectively). Optimal shoot multiplication and rooting were obtained on 1.0 mg/l BAP and 0.1 mg/l IBA, respectively, followed by acclimatization of regenerants to greenhouse conditions. This work aims at establishing protocol for A. annua preservation and biosynthesis of natural products. Plant Tissue Cult. & Biotech. 30(1): 97-106, 2020 (June)


Plant Science ◽  
1996 ◽  
Vol 116 (2) ◽  
pp. 223-232 ◽  
Author(s):  
Andrew M.G. Brown ◽  
Kenneth C. Lowe ◽  
Michael R. Davey ◽  
J.Brian Power

2014 ◽  
Vol 2 (1) ◽  
pp. 46-51
Author(s):  
Shirzad Gholami ◽  
Mohammad Azadbakht ◽  
Hajar Ziaei Hezarjaribi ◽  
Bahman Rahimi-Esboei ◽  
◽  
...  

2019 ◽  
Vol 54 ◽  
pp. 12-23 ◽  
Author(s):  
Arman Beyraghdar Kashkooli ◽  
Alexander R. van der Krol ◽  
Patrick Rabe ◽  
Jeroen S. Dickschat ◽  
Harro Bouwmeester

2018 ◽  
Vol 10 (4) ◽  
pp. 251-255 ◽  
Author(s):  
AMALIA INDAH PRIHANTINI ◽  
AGUS SUKITO ◽  
SANRO TACHIBANA

Prihantini AI, Sukito A, Tachibana S. 2018. Production of antioxidant compound from tissue culture of Artemisia annua. Nusantara Bioscience 10: 251-255. Phenolic compounds have attracted much attention because of their role in some oxidative diseases. Therefore, the study aimed to investigate the production of antioxidant compound from tissue culture of A. annua. The callus were developed on solid MS medium treated with four combination of plant growth regulators: NAA 0.5 mg/L + BA 0.5 mg/L; NAA 0.5 mg/L + kinetin 0.5 mg/L; 2,4-D 0.5 mg/L + BA 0.5 mg/L; and 2,4-D 0.5 mg/L+ kinetin 0.5 mg/L. The callus extracts were evaluated their antioxidant activity and were analyzed the content of phenolic content. Furthermore, detection and quantification of phenolic compound were investigated. Combination of NAA 0.5 mg/L + BA 0.5 mg/L showed the highest DPPH radical scavenging activity and total phenolic content. GCMS analysis also revealed that the combination also showed the highest content of caffeic acid, a phenolic compound known as an antioxidant agent. Furthermore, the callus extract treated with NAA 0.5 mg/L + BA 0.5 mg/L increased both the antioxidant activity and caffeic acid content compared with A. annua leaf extract. In conclusion, plant tissue culture enhanced pharmaceutical properties of A. annua. Moreover, the study suggested that the treated callus extract of A. annua is potential to be further developed for production of antioxidant compound.


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