An in vitro Evaluation of Antimicrobial Efficacy of Primary Root Canal Filling Materials

2012 ◽  
Vol 37 (1) ◽  
pp. 59-64 ◽  
Author(s):  
Hegde Sapna ◽  
Lala Priti Kamlesh ◽  
B Dinesh Rao ◽  
AB Shubha
Keyword(s):  
Zinc Oxide ◽  
Calcium Hydroxide ◽  
Sodium Fluoride ◽  
Root Canal ◽  
Antimicrobial Efficacy ◽  
Root Canal Filling ◽  
Root Canals ◽  
Filling Materials ◽  
Zinc Oxide Eugenol

Objective: The present study aimed to evaluate and compare six different materials commonly used for filling the root canals of primary teeth for antimicrobial efficacy against some of the microorganisms commonly found in infected root canals. Study design: In this experimental in vitro study six root canal filling materials were tested for antimicrobial efficacy against eight microbial strains using the agar diffusion method. Results: Zinc oxide eugenol paste exhibited the strongest antimicrobial potential followed by Endoflas™, zinc oxide-calcium hydroxide-sodium fluoride mixture, zinc oxide-calcium hydroxide mixture and calcium hydroxide paste (Apexcal™). The addition of sodium fluoride to the zinc oxide-calcium hydroxide mixture enhanced the antimicrobial efficacy. Metapex™ demonstrated minimal inhibition and Vaseline™ was non-inhibitory. Conclusions: All the test filling materials demonstrated varying antimicrobial activity against the microorganisms tested. Zinc oxide eugenol paste and materials containing zinc oxide were found to be more effective against the microorganisms compared to materials without zinc oxide.

scholarly journals Antimicrobial activity of root canal filling materials

2021 ◽  
Vol 7 (1) ◽  
pp. 01-05
Author(s):  
Jikia Maia
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Zinc Oxide ◽  
Antimicrobial Properties ◽  
Root Canal Filling ◽  
Root Canals ◽  
Filling Materials ◽  
Zinc Oxide Eugenol ◽  
Test Culture

The antimicrobial activity of filling materials was studied to improve the quality of treatment of complicated caries in vitro. Resorcin-formalin cement Resodont (“Latus”, Ukraine) - № 1; Endocort zinc oxide-eugenol cement (“Latus”, Ukraine) - No. 2; materials based on zinc oxide eugenol cement with dexamethasone: Endomethasone ivory (Septodont, France) - No. 3 and Endofil ("Produit Dentaires SA", Switzerland) - No. 4. To assess the antimicrobial activity of the studied materials, test microorganism strains were used: Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 6783, Candida albicans ATCC 885-653. As a result of the study, it was established that filling materials have different antimicrobial activity. Resodont has the greatest antimicrobial activity on the test culture. Endomethason is active in relation to the test cultures studied, inferior to Resodont in its antimicrobial properties. Endocort and Endofil have less antimicrobial activity than Resodont and Endomethason, but have approximately equal growth retardation rates. It should be noted that with respect to Staphylococcus aureus, Endocort was found to be almost 1.5 times more active than Endofil. The conducted studies confirm that the materials for filling of root canals by Resodont and Endocort (Latus, Ukraine) have a pronounced antibacterial effect. They are competitive with foreign sealers and are the materials of choice, having a significantly lower cost.

Endoflas, Zinc Oxide Eugenol and Metapex as Root Canal Filling Materials in Primary Molars—A Comparative Clinical Study

2011 ◽  
Vol 35 (4) ◽  
pp. 365-370 ◽  
Author(s):  
Priya Subramaniam ◽  
Kanupriya Gilhotra
Keyword(s):  
Zinc Oxide ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
Primary Molars ◽  
Filling Material ◽  
Root Canal Filling ◽  
Filling Materials ◽  
Zinc Oxide Eugenol ◽  
Root Canal Filling Materials ◽  
Significant Difference

Several materials have been used to fill root canals of primary teeth. Traditionally, zinc oxide eugenol was used for the purpose, until the introduction of calcium hydroxide and iodoform based materials. Another root canal filling material that contains zinc oxide eugenol, calcium hydroxide and iodoform is commercially available as Endoflas. The aim of the study was to evaluate and compare the efficacy of Endoflas, zinc oxide eugenol and Metapex as root canal filling materials. Method: A total of forty-five primary molars from children aged 5-9 years were selected for a one stage pulpectomy procedure. Teeth were randomly divided into three groups of fifteen teeth each based on the type of root canal filling material used. All the molars were evaluated clinically and radiographically at regular intervals of 3, 6, 12 and 18 months. The observations were tabulated and statistically analyzed. Results: Endoflas and zinc oxide eugenol showed 93.3% success, whereas a higher percentage of success was observed with Metapex (100%). Overfilling and voids were more commonly seen in teeth filled with Metapex. Conclusion: There was no significant difference between the three root canal filling materials.

scholarly journals Sealability of Different Root Canal Nanosealers: Nano Calcium Hydroxide and Nano Bioactive Glass

2019 ◽  
Vol 13 (1) ◽  
pp. 308-315
Author(s):  
Asmaa A. Desouky ◽  
Maged M. Negm ◽  
Magdy M. Ali
Keyword(s):  
Zinc Oxide ◽  
Bioactive Glass ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
Blue Dye ◽  
Nano Powder ◽  
Zinc Oxide Eugenol ◽  
Nail Polish ◽  
Stereo Microscope

Background: The success of the endodontic treatment is largely dependent on the sealing achieved by root canal obturation. The application of sealer fills imperfections and increases adaptation of the root filling to the canal walls. Aim: To evaluate the sealability of experimental nanosealers (nano calcium hydroxide and nano bioactive glass) and to compare it with the commercial zinc oxide eugenol sealer using a dye penetration method. Materials and Methods: Sixty single-rooted mandibular premolars were selected. The tooth crowns were removed so as to obtain standardized 15-mm-long root specimens. The root canal was instrumented with Protaper Ni-Ti rotary file and the final file size was up to # F4/.06 (in vitro study). They were then randomly allocated into 3 groups of 20 specimens each (n=20) according to the sealer used for obturation, and all samples were filled with single cone gutta-percha (#40/06) and one of the tested sealers. All teeth were coated with nail polish and then suspended in 2% methylene blue dye for 7 days. Stereo-microscope (x10) was used to evaluate the sealability of newly introduced nanosealers. The data were statistically analyzed by ANOVA test followed by post hoc analysis (P < 0.05). Results: Significant improvement shown by the presented study suggests that nano calcium hydroxide sealer showed significantly less dye leakage than nano bioactive glass sealer and zinc oxide eugenol sealer. Conclusion: The results of this study showed that the synthesized nano-powder sealers are suitable for use in root canal therapy to prevent leakage. The root canal can be sealed better by using smaller nano-powder particle sizes. In addition, the two groups exhibited significant differences in leakage in comparison with commonly used ZOE sealer.

scholarly journals Antibacterial activity of root canal filling materials for primary teeth: zinc oxide and eugenol cement, Calen paste thickened with zinc oxide, Sealapex and EndoREZ

2009 ◽  
Vol 20 (4) ◽  
pp. 290-296 ◽  
Author(s):  
Alexandra Mussolino de Queiroz ◽  
Paulo Nelson Filho ◽  
Léa Assed Bezerra da Silva ◽  
Sada Assed ◽  
Raquel Assed Bezerra da Silva ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Root Canal ◽  
Primary Teeth ◽  
Bacterial Strains ◽  
Root Canal Filling ◽  
Filling Materials ◽  
Root Canal Filling Materials ◽  
Bacterial Growth Inhibition

This study evaluated in vitro the antibacterial activity of 4 root canal filling materials for primary teeth - zinc oxide and eugenol cement (ZOE), Calen paste thickened with zinc oxide (Calen/ZO), Sealapex sealer and EndoREZ sealer - against 5 bacterial strains commonly found in endodontic infections (Kocuria rhizophila, Enterococcus faecalis, Streptococcus mutans, Escherichia coli and Staphylococcus aureus) using the agar diffusion test (agar-well technique). Calen paste, 1% chlorhexidine digluconate (CHX) and distilled water served as controls. Seven wells per dish were made at equidistant points and immediately filled with the test and control materials. After incubation of the plates at 37oC for 24 h, the diameter of the zones of bacterial growth inhibition produced around the wells was measured (in mm) with a digital caliper under reflected light. Data were analyzed statistically by analysis of variance and Tukey's post-hoc test (?=0.05). There were statistically significant differences (p<0.0001) among the zones of bacterial growth inhibition produced by the different materials against all target microorganisms. K. rhizophila was inhibited more effectively (p<0.05) by ZOE, while Calen/ZO had its highest antibacterial activity against E. faecalis (p<0.05). S. mutans was inhibited by Calen/ZO, Sealapex and ZOE in the same intensity (p>0.05). E. coli was inhibited more effectively (p<0.05) by ZOE, followed by Calen/ZO and Sealapex. Calen/ZO and ZOE were equally effective (p>0.05) against S. aureus, while Sealapex had the lowest antibacterial efficacy (p<0.05) against this microorganism. EndoREZ presented antibacterial activity only against K. rhizophila and S. aureus. The Calen paste and Calen/ZO produced larger zones of inhibition than 1% CHX when the marker microorganism was E faecalis. In conclusion, the in vitro antibacterial activity of the 4 root canal filling materials for primary teeth against bacterial strains commonly found in endodontic infections can be presented in a decreasing order of efficacy as follows: ZOE>Calen/ZO>Sealapex>EndoREZ.

scholarly journals Volumetric Assessment of Root Canal Obturation Using 3% Nano-Chitosan Versus Zinc Oxide Eugenol (ZOE) and Iodoform-Calcium Hydroxide (Metapex), in Primary Root Canals Shaped with Rotary Versus Manual Methods: A Preliminary In-Vitro Spiral CT Study

2019 ◽  
Author(s):  
Elahe Babashahi ◽  
Maryam Mohmadi Kartalaie ◽  
Leila Basir ◽  
Vahid Rakhshan4
Keyword(s):  
Zinc Oxide ◽  
Calcium Hydroxide ◽  
Primary Root ◽  
In Vitro Study ◽  
The Other ◽  
Root Canals ◽  
Zinc Oxide Eugenol ◽  
Volumetric Assessment ◽  
The Difference

Objectives: In this study, chitosan was introduced and used as a substitute for pulpectomy obturation against conventional materials: zinc oxide eugenol (ZOE) and iodoform-calcium hydroxide (Ca(OH)2) compounds. Also, efficacies of rotary versus manual instrumentations were compared. Materials and Methods: This preliminary in-vitro study was performed on 152 intact non-resorbed root canals of primary molars divided into rotary (n=78) versus hand-instrumentation (n=74) and also into ZOE (n=53), iodoform-Ca(OH)2 (n=50), and 3% nano-chitosan (n=49). Canals were cleaned/shaped using hand or rotary files. Canal spaces were measured using spiral computed tomography (CT). Canals were then obturated using the three materials. The percentages of obturation volume (POV) were estimated. Rotary and manual instrumentations were compared in terms of canal spaces before and after obturation. Three obturation materials were compared in terms of canal spaces after obturation (α=0.05). Results: Average POVs of materials were 96.54% (ZOE), 97.87% (Metapex), and 74.74% (nano-chitosan; P=0.000). POV of chitosan differed from the other two (P=0.000) but the other two were similar (P=0.896). Average POVs were 91.46% (manual) and 88.51% (rotary); the difference was not significant (P=0.322). Pre-obturation spaces of canals for different methods were 3.89 mm3 (manual) and 3.26 mm3 (rotary); the difference was significant (P=0.013). Two-way ANCOVA showed a significant effect of materials (P=0.000) but not root length (P=0.585) or shaping methods (P=0.362) on POVs. Conclusions: Nano-chitosan showed a considerable success rate but it still needs reformulation as it was weaker than the extremely successful commercial competitors. Rotary instrumentation can provide results similar to hand-filing in terms of POV although it might yield smaller canals.

Evaluation of Antimicrobial Efficacy of Various Root Canal Filling Materials Used in Primary Teeth: A Microbiological Study

2007 ◽  
Vol 31 (3) ◽  
pp. 193-198 ◽  
Author(s):  
S Reddy ◽  
Y Ramakrishna
Keyword(s):  
Zinc Oxide ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
Primary Teeth ◽  
Endodontic Treatment ◽  
Root Canal Filling ◽  
Primary Molar ◽  
Filling Materials ◽  
Root Canal Filling Materials ◽  
Antimicrobial Effectiveness

The primary goal of endodontic treatment in primary teeth is to eliminate infection, and to retain the tooth in a functional state until their normal exfoliation time without endangering the permanent dentition or the general health of the child. The complexity of the pulp canal system in primary teeth presents a discerning problem for chemo-mechanical preparation. One of the factors determining the success of endodontic treatment in infected primary teeth is the sealing material that should encompass among other factors a potent bactericidal effect and the capacity to resorb along with the roots of primary teeth. This study evaluated the antimicrobial effectiveness of 5 root canal filling materials and a negative control agent against 23 strains of bacteria isolated from infected root canals of primary molar teeth and 3 non standard bacterial strains using agar diffusion assay. The materials were Zinc oxide and Eugenol (ZOE), Zinc oxide-Eugenol and Formocresol (ZOE+FC), Calcium hydroxide and sterile water (CAOH+H2O), Zinc oxide and Camphorated phenol (ZO+CP), Calcium hydroxide and Iodoform (Metapex) and Vaseline (Control). All the materials except Vaseline showed varied antimicrobial activity against the test bacteria. The zones of inhibition were ranked into 4 inhibition categories based on the proportional distribution of the data. All the 26 bacterial isolates were classified under 4 groups based on Aerobic/Anaerobic and Gram positive/Gram negative. Statistical analysis was carried out to compare the antimicrobial effectiveness between materials tested with each of the bacterial groupings. ZOE+FC produced strong inhibition against most bacteria when compared to ZOE, ZO+CP and CAOH+H2O. Metapex and Vaseline were found to be non inhibitory

Comparative Evaluation of Antimicrobial Efficacy of Various Root Canal Filling Materials Along with Aloevera Used in Primary Teeth: A Microbiological Study

2013 ◽  
Vol 37 (3) ◽  
pp. 257-262 ◽  
Author(s):  
R Kriplani ◽  
N Thosar ◽  
M S Baliga ◽  
P Kulkarni ◽  
N Shah ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Zinc Oxide ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
Sterile Water ◽  
Root Canal Filling ◽  
Primary Molar ◽  
Filling Materials ◽  
Root Canal Filling Materials ◽  
Antimicrobial Effectiveness

Aim: this study was conducted to evaluate the antimicrobial effectiveness of 6 root canal filling materials and a negative control agent against 18 strains of bacteria isolated from infected root canals of primary molar teeth using agar diffusion assay. Materials: Aloevera with sterile water, Zinc oxide and Eugenol, Zinc oxide-Eugenol with aloevera, Calcium hydroxide and sterile water, Calcium hydroxide with sterile water and aloevera, Calcium hydroxide and Iodoform (Metapex) and Vaseline (Control). MIC and MBC of aloevera was calculated. Results: All materials except Vaseline showed varied antimicrobial activity against the test bacterias. The zones of inhibition were ranked into 4 inhibition categories based on the proportional distribution of the data. All the 18 bacterial isolates were classified under 2 groups based on Gram positive and Gram negative aerobes. Statistical analysis was carried out to compare the antimicrobial effectiveness between materials tested with each of the bacterial groupings. Conclusion: Aloevera + Sterile Water was found to have superior antimicrobial activity against most of the microorganisms followed by ZOE + Aloevera, calcium hydroxide + Aloevera, ZOE, calcium hydroxide, Metapex in the descending order and Vaseline showed no inhibition.

scholarly journals Comparative Evaluation of Calcium Hydroxide and Zinc Oxide Eugenol as Root Canal Filling Materials for Primary Molars: A Clinical and Radiographic Study

2011 ◽  
Vol 2 (3) ◽  
pp. 231-236 ◽  
Author(s):  
Shikha Dogra
Keyword(s):  
Zinc Oxide ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
Primary Teeth ◽  
Radiographic Examination ◽  
Filling Material ◽  
Root Canal Filling ◽  
Zinc Oxide Eugenol ◽  
Group I ◽  
Group Ii

ABSTRACT Aim The purpose of this study is to compare the efficacy of calcium hydroxide and zinc oxide eugenol as a root canal filling material in primary teeth using endodontic pressure syringe system. Materials and methods A total of 40 primary mandibular molars were selected and divided into two groups-group I (calcium hydroxide was used as root canal filling material) and group II (zinc oxide eugenol used as canal filling material). Clinical review was undertaken at 1, 3, 6 and 9 months interval for evaluating pain, tenderness, mobility and any other sign of pathology. Radiographic examination was done at interval of 3, 6 and 9 months for the evaluation of any change in the radiolucency around the apices and inter-radicular space. Resorption of root and filling material was also assessed. Results Reduction in the clinical symptoms were noted in both groups (p < 0.01). All the 20 cases in group I demonstrated a decrease in size of radiolucency. However in group II, an increase in radiolucency was observed in 2 teeth at 3 months radiographic examination. Further no decrease in the size of radiolucency was noticed at subsequent follow-up visits. Complete resorption of overfilled material was observed at the 3 months radiographic examination for group I whereas partial resorption of overfilled material was seen at 6 months radiographic examination for group II. Conclusion The findings of the present study indicate that calcium hydroxide could be used exclusively or as an alternative to zinc oxide eugenol as a root canal filling material for the primary teeth.

scholarly journals A Systematic Review of Root Canal Filling Materials for Deciduous Teeth: Is There an Alternative for Zinc Oxide-Eugenol?

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Fernanda Barja-Fidalgo ◽  
Michele Moutinho-Ribeiro ◽  
Maria Angelina Amorim Oliveira ◽  
Branca Heloísa de Oliveira
Keyword(s):  
Systematic Review ◽  
Zinc Oxide ◽  
Calcium Hydroxide ◽  
Root Canal ◽  
Convincing Evidence ◽  
The Other ◽  
Deciduous Teeth ◽  
Success Rates ◽  
Root Canal Filling ◽  
Zinc Oxide Eugenol

The aim of this systematic review was to determine whether there is a root canal filling for deciduous teeth equally or more effective than zinc oxide-eugenol cement (ZOE). Six clinical trials selected for inclusion were independently reviewed by two researchers. Only two showed statistically significant different success rates between the test and the control groups. One found that an iodoform paste with calcium hydroxide () performed better than ZOE, and the other found that ZOE performed similarly to . The other four studies compared ZOE with an iodoform paste (IP), a calcium hydroxide cement , or . In these trials, the success rates in the ZOE groups were slightly lower than in the other groups. There seems to be no convincing evidence to support the superiority of any material over ZOE, and both ZOE and appear to be suitable as root canal fillings for deciduous teeth.

Sign in / Sign up

Export Citation Format

Share Document