scholarly journals Influence of pulse magnitotepapy on capillary blood flow indicators in complex treatment of patients with gonarthrosis

2021 ◽  
Vol 19 (3) ◽  
pp. 160-170
Author(s):  
Yu. Yu. Byalovsky ◽  
A. V. Ivanov ◽  
T. N. Zaytseva ◽  
I. S. Evstigneeva
Keyword(s):  
Blood Flow ◽  
Magnetic Fields ◽  
High Efficiency ◽  
Main Group ◽  
Capillary Blood ◽  
Capillary Blood Flow ◽  
Osteoarthritis Of The Knee ◽  
Outer Corner ◽  
Capillary Bed ◽  
Flow Through

Background.Today, osteoarthritis, in particular its clinical form of gonarthrosis, is the most common degenerative-dystrophic diseases of the joints in practice in all countries. The objective:of the present study was to estimate the efficacy of local pulsed magnetotherapy on capillary blood flow in patients with osteoarthritis of the knee joint. Methods.A total of 50 patients aged from 36 to 65 years with IIII stage gonarthrosis. All patients of the main group (n=25) received treatment with a pulsed magnetic field and NSAID therapy (diclofenac 25 mg 3 times a day, course 15 days). Patients in the comparison group (n=25) received only NSAIDs. The functional state of the capillary bed was assessed by biomicroscopy of the vessels of the outer corner of the eye using a fiber optic ophthalmoscope with a Riester Ri-ScopeL diode lamp (Germany). The state of the vessels of the angle of the eye was assessed by capillary (KI1) intravascular (KI2), extravascular (KI3) and general (KIgen) indices. Results.After a course of local pulsed magnetotherapy, normalization of the ateriol-venular ratio, restoration of blood flow through the capillaries and the disappearance of a cloudy background were noted in all patients of the main group. After 6 months, the found changes were preserved in the patients of the main group, while in patients receiving NSAID mototherapy, all positive changes from the capillary blood flow disappeared. Conclusions.In recent years, magnetotherapy, both general and local, has been successfully used to treat patients with gonarthrosis. One of the mechanisms of action of magnetic fields is to improve microcirculation in tissues. The therapeutic effect of magnetic fields in gonarthrosis has been studied, and its high efficiency has been proven.

scholarly journals THE RELATION OF ANGIOTONIN AND L-NOREPINEPHRINE TO ESSENTIAL HYPERTENSION AS DETERMINED BY THE REACTION OF THE NAILFOLD CAPILLARY BED

1956 ◽  
Vol 103 (4) ◽  
pp. 477-486 ◽  
Author(s):  
Sheldon E. Greisman
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Essential Hypertension ◽  
Arterial Blood Pressure ◽  
Reactive Hyperemia ◽  
Capillary Blood ◽  
Capillary Blood Flow ◽  
Arterial Blood ◽  
Capillary Bed ◽  
Diastolic Arterial Blood Pressure

Further evidence has been obtained that L-norepinephrine infusions markedly decreases cutaneous capillary blood flow in the nailfold. Sustained ischemia of the capillary bed occurred prior to the attainment of hypertensive diastolic arterial blood pressure levels. Corroborative evidence of this nailfold capillary ischemia was obtained from the capillary reactive hyperemia that followed the abrupt discontinuance of the L-norepinephrine infusions. The infusion of angiotonin into persons with normal blood pressure did not induce sustained ischemia of the nailfold capillary vessels, even after definite hypertensive diastolic arterial blood pressure levels were attained. Corroboration of the adequacy of nailfold capillary blood flow was obtained by noting the absence of capillary reactive hyperemia following the abrupt cessation of the angiotonin infusions. The nailfold capillary bed in persons with angiotonin-induced hypertension could not be distinguished from that of persons with essential hypertension by direct microscopic examination. During the infusion of angiotonin into subjects with normal cardiovascular systems, the reactivity of the nailfold capillary bed to circulating L-norepinephrine was significantly increased, approaching the levels found in persons with essential hypertension. From the standpoint of its effects upon the nailfold capillary bed, angiotonin, unlike L-norepinephrine, is one substance which possesses the properties required of the hypothetical humoral pressor substance of essential hypertension.

Lutein Complex Supplementation Increases Ocular Blood Flow Biomarkers in Healthy Subjects

2019 ◽  
Vol 89 (1-2) ◽  
pp. 5-12
Author(s):  
Alon Harris ◽  
Brent Siesky ◽  
Amelia Huang ◽  
Thai Do ◽  
Sunu Mathew ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Diastolic Blood Pressure ◽  
Healthy Subjects ◽  
Ocular Blood Flow ◽  
Capillary Blood ◽  
Post Treatment ◽  
Capillary Blood Flow ◽  
Doppler Imaging ◽  
Retinal Capillary

Abstract. Introduction: To investigate the effects of a lutein complex supplementation on ocular blood flow in healthy subjects. Materials and Methods: Sixteen healthy female patients (mean age 36.8 ± 12.1 years) were enrolled in this randomized, placebo-controlled, double-blinded, two-period crossover study. Subjects received daily an oral dose of the lutein with synergistic phytochemicals complex (lutein (10 mg), ascorbic acid (500 mg), tocopherols (364 mg), carnosic acid (2.5 mg), zeaxanthin (2 mg), copper (2 mg), with synergistic effects in reducing pro-inflammatory mediators and cytokines when administered together in combination) and placebo during administration periods. Measurements were taken before and after three-week supplementation periods, with crossover visits separated by a three-week washout period. Data analysis included blood pressure, heart rate, intraocular pressure, visual acuity, contrast sensitivity detection, ocular perfusion pressure, confocal scanning laser Doppler imaging of retinal capillary blood flow, and Doppler imaging of the retrobulbar blood vessels. Results: Lutein complex supplementation produced a statistically significant increase in mean superior retinal capillary blood flow, measured in arbitrary units (60, p = 0.0466) and a decrease in the percentage of avascular area in the superior (−0.029, p = 0.0491) and inferior (−0.023, p = 0.0477) retina, as well as reduced systolic (−4.06, p = 0.0295) and diastolic (−3.69, p = 0.0441) blood pressure measured in mmHg from baseline. Data comparison between the two supplement groups revealed a significant decrease in systemic diastolic blood pressure (change from pre- to post-treatment with lutein supplement (mean (SE)): −3.69 (1.68); change from pre- to post-treatment with placebo: 0.31 (2.57); p = 0.0357) and a significant increase in the peak systolic velocity (measured in cm/sec) in the central retinal artery (change from pre- to post-treatment with lutein supplement: 0.36 (0.19); change from pre- to post-treatment with placebo: −0.33 (0.21); p = 0.0384) with lutein complex supplement; data analyses from the placebo group were all non-significant. Discussion: In healthy participants, oral administration of a lutein phytochemicals complex for three weeks produced increased ocular blood flow biomarkers within retinal vascular beds and reduced diastolic blood pressure compared to placebo.

FEATURES OF CAPILLARY BLOOD FLOW IN PATIENTS WITH PATHOLOGY OF INTRANASAL STRUCTURES AND NASAL BREATHING DISORDERS

2020 ◽  
pp. 53-59
Author(s):  
N. O. Shushliapina ◽  
O. Ye. Cherniakova
Keyword(s):  
Blood Flow ◽  
Vascular Tissue ◽  
Circulatory System ◽  
Capillary Blood ◽  
The State ◽  
Capillary Blood Flow ◽  
Nasal Breathing ◽  
Breathing Disorders ◽  
Special Software ◽  
Capillary Circulation

The investigation of the vascular microcirculation system is important for diagnosis, assessment of the severity and nature of pathological processes in human body, monitoring the effectiveness of treatment. Monitoring the state of microcirculation in impaired respiratory function of the nose helps to study the subtle mechanisms of regulation of vascular−tissue relations. To do this, there were used the biomicroscopic methods to study capillary blood flow, one of the most relevant and promising is optical capillaroscopy of the nail bed. This method makes it possible to identify at the evidence level the peculiarities of the functioning of the peripheral circulatory system by the state of the capillary system and to evaluate the effectiveness of treatment by the rheological properties of blood in hematological practice. There were examined 145 patients by means of computer capillaroscopy to study the rate of capillary circulation in the patients with pathology of intranasal structures and nasal breathing disorders. All patients underwent a complete clinical examination, routine instrumental examinations, and computer capillaroscopy using a video capillaroscope with a visual magnification of up to 550 times. The obtained images were stored and processed according to a special software. During the characterization of the capillaroscopic picture there were evaluated: pathological tortuosity, change in the caliber of arterioles and venules, disorganization of the capillary network, the number of functioning capillaries. Changes in the speed and nature of capillary blood flow (accelerated, slow, stasis) were observed. The optical capillaroscopy method allows not only to visually assess the condition of microvessels, but also to determine such an important parameter as blood circulation, actually, it can replace the study of laser Doppler. Such data will be important in the diagnosis of respiratory and olfactory disorders and the formation of adequate tactics for their treatment. Key words: microcirculation, microcirculatory tract, capillary circulation, nasal obstruction, nasal breathing disorders, pathology of intranasal structures, computer capillaroscopy.

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