scholarly journals Features of a craniocerebral injury received against the background of craniostenosis

1982 ◽  
Vol 63 (6) ◽  
pp. 9-11
Author(s):  
A. L. Kirillov
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Cerebral Edema ◽  
Craniocerebral Injury ◽  
Brain Contusion ◽  
Injury Causes ◽  
Dehydration Therapy

Examined 87 patients with craniostenosis at the age from 3 to 14 years, who had suffered a moderate craniocerebral injury. It was found that in the stage of compensation, a relatively mild traumatic brain injury leads to mild brain contusion. Treatment of patients in this category should be conservative, but longer than in patients without concomitant craniostenosis. In the decompensated stage of craniostenosis, a similar injury causes the development of moderate brain contusion. With severe cerebral edema, flap craniotomy is indicated, since conventional dehydration therapy is ineffective.

scholarly journals Repeated mild traumatic brain injury causes focal response in lateral septum and hippocampus

Concussion ◽  
2016 ◽  
Vol 1 (3) ◽  
pp. CNC13 ◽  
Author(s):  
Rebecca Acabchuk ◽  
Denise I Briggs ◽  
Mariana Angoa-Pérez ◽  
Meghan Powers ◽  
Richard Wolferz ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Lateral Septum ◽  
Injury Causes

scholarly journals Repetitive Mild Traumatic Brain Injury Causes Optic Nerve and Retinal Damage in a Mouse Model

2014 ◽  
Vol 73 (4) ◽  
pp. 345-361 ◽  
Author(s):  
Radouil Tzekov ◽  
Alexandra Quezada ◽  
Megan Gautier ◽  
Davida Biggins ◽  
Candice Frances ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Optic Nerve ◽  
Mouse Model ◽  
Mild Traumatic Brain Injury ◽  
Retinal Damage ◽  
Injury Causes

scholarly journals Repetitive mild traumatic brain injury causes synergistic effects on mortality

2020 ◽  
Author(s):  
Ashley M Willes ◽  
Tori R Krcmarik ◽  
Alexander E Daughtry ◽  
Douglas J Brusich
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Synergistic Effect ◽  
Mild Traumatic Brain Injury ◽  
Synergistic Effects ◽  
High Impact ◽  
Critical Number ◽  
Poor Understanding ◽  
Injury Causes ◽  
The U.S

AbstractRepetitive mild TBI (rmTBI) events are common in the U.S. However, rmTBI is challenging to study and this contributes to a poor understanding of mechanistic bases for disease following these injuries. We used fruit flies (D. melanogaster) and a modified version of the high-impact trauma (HIT) method of TBI to assess the pattern of mortality observed after rmTBI. We found that the pattern of mortality was synergistic after a critical number of injuries, similar to that observed previously at more moderate levels of TBI severity. The identity of cellular and molecular factors which contribute to the synergistic effect on mortality remain unknown, but this model offers a platform for investigation into such factors.

scholarly journals Shape effect of cerium oxide nanoparticles on mild traumatic brain injury

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dong Hyuk Youn ◽  
Ngoc Minh Tran ◽  
Bong Jun Kim ◽  
Youngmi Kim ◽  
Jin Pyeong Jeon ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Cerebral Edema ◽  
High Energy ◽  
Control Group ◽  
Mrna Levels ◽  
Ceria Nanoparticles ◽  
Fluoro Jade B

AbstractThe catalytic performance and therapeutic effect of nanoparticles varies with shape. Here, we investigated and compared the therapeutic outcomes of ceria nanospheres (Ceria NSs) and ceria nanorods (Ceria NRs) in an in vivo study of mild traumatic brain injury (mTBI). In vivo TBI was induced in a mouse model of open head injury using a stereotaxic impactor. Outcomes including cytoprotective effects, cognitive function, and cerebral edema were investigated after retro-orbital injection of 11.6 mM of ceria nanoparticles. Ceria nanoparticles significantly reduced fluoro-jade B (FJB)-positive cells and terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL)-positive cells, and restored mRNA levels of superoxide dismutase 1 (SOD1) and SOD2. They also decreased the cyclooxygenase-2 (COX-2) expression compared with the untreated control group. Comparing the two nanomaterials, Ceria NRs showed less stable and high-energy (100) and (110) planes, which increased the number of active sites. The Ce3+/Ce4+ molar ratio of Ceria NRs (0.40) was greater than that of Ceria NSs (0.27). Ceria NRs (0.059 ± 0.021) appeared to exhibit better anti-inflammatory effect than Ceria NSs (0.133 ± 0.024), but the effect was statistically insignificant (p = 0.190). Ceria nanoparticles also improved cognitive impairment following mTBI compared with the control group, but the effect did not differ significantly according to the nanoshape. However, Ceria NRs (70.1 ± 0.5%) significantly decreased brain water content compared with Ceria NSs (73.7 ± 0.4%; p = 0.0015), indicating a more effective reduction in brain edema (p = 0.0015). Compared with Ceria NSs, the Ceria NRs are more effective in alleviating cerebral edema following in vivo mTBI.

scholarly journals Repetitive Diffuse Mild Traumatic Brain Injury Causes an Atypical Astrocyte Response and Spontaneous Recurrent Seizures

2019 ◽  
Vol 39 (10) ◽  
pp. 1944-1963 ◽  
Author(s):  
Oleksii Shandra ◽  
Alexander R. Winemiller ◽  
Benjamin P. Heithoff ◽  
Carmen Munoz-Ballester ◽  
Kijana K. George ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Spontaneous Recurrent Seizures ◽  
Injury Causes

FEATURES OF CEREBRAL CIRCULATORY DYNAMICS AND CEREBRAL BIOELECTRIC ACTIVITY IN CHILDREN WITH CRANIOCEREBRAL INJURY

2020 ◽  
pp. 55-59
Author(s):  
Viktoriia Mykolaivna Petrenko
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Transcranial Doppler Sonography ◽  
Cerebral Hemodynamics ◽  
Bioelectrical Activity ◽  
Craniocerebral Injury ◽  
Paroxysmal Activity ◽  
Brain Contusion ◽  
Epidural Hemorrhage ◽  
Circulatory Dynamics

In order to study the state of cerebral hemodynamics and to investigate the electroencephalographic characteristics in children with closed traumatic brain injury, 114 patients were examined. The children were examined in 6.1±0.8 months after a traumatic brain injury. To determine cerebral hemodynamics, transcranial dopplerography was performed, the functional state of brain was evaluated according to electroencephalography. In the course of the study, it was noted that a disordered cerebral hemodynamics in children with moderate and severe brain contusion and its foci presence was accompanied by a rise in a linear velocity of blood flow, while its decrease was found at the same contusion, but that was severe and with the presence of subdural, subarachnoid and epidural hemorrhage. Signs of diffuse changes in bioelectrical activity of the brain were represented by a significant increase in an amplitude of the alpha rhythm in children with closed traumatic brain injury of moderate and serious severities compared to mild one. Key words: children, craniocerebral injury, electroencephalography, transcranial Doppler sonography, paroxysmal activity.

Brain contusion as the main risk factor of memory or emotional complaints in chronic complicated mild traumatic brain injury

Brain Injury ◽  
2017 ◽  
Vol 31 (5) ◽  
pp. 601-606 ◽  
Author(s):  
Bei-Yi Su ◽  
Nai-Wen Guo ◽  
Nan-Chun Chen ◽  
Sheng-Sian Lin ◽  
Ming-Tsung Chuang ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Risk Factor ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Main Risk Factor ◽  
Brain Contusion

The Speech-Language Pathologists' Role in Mild Traumatic Brain Injury for Middle and High School–Age Children: Viewpoints on Guidelines From the Centers for Disease Control and Prevention

2019 ◽  
Vol 28 (3) ◽  
pp. 1363-1370 ◽  
Author(s):  
Jessica Brown ◽  
Katy O'Brien ◽  
Kelly Knollman-Porter ◽  
Tracey Wallace
Keyword(s):  
High School ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Disease Control ◽  
Mild Traumatic Brain Injury ◽  
School Age Children ◽  
School Age ◽  
Speech Language Pathologists ◽  
Control And Prevention ◽  
Centers For Disease Control

Purpose The Centers for Disease Control and Prevention (CDC) recently released guidelines for rehabilitation professionals regarding the care of children with mild traumatic brain injury (mTBI). Given that mTBI impacts millions of children each year and can be particularly detrimental to children in middle and high school age groups, access to universal recommendations for management of postinjury symptoms is ideal. Method This viewpoint article examines the CDC guidelines and applies these recommendations directly to speech-language pathology practices. In particular, education, assessment, treatment, team management, and ongoing monitoring are discussed. In addition, suggested timelines regarding implementation of services by speech-language pathologists (SLPs) are provided. Specific focus is placed on adolescents (i.e., middle and high school–age children). Results SLPs are critical members of the rehabilitation team working with children with mTBI and should be involved in education, symptom monitoring, and assessment early in the recovery process. SLPs can also provide unique insight into the cognitive and linguistic challenges of these students and can serve to bridge the gap among rehabilitation and school-based professionals, the adolescent with brain injury, and their parents. Conclusion The guidelines provided by the CDC, along with evidence from the field of speech pathology, can guide SLPs to advocate for involvement in the care of adolescents with mTBI. More research is needed to enhance the evidence base for direct assessment and treatment with this population; however, SLPs can use their extensive knowledge and experience working with individuals with traumatic brain injury as a starting point for post-mTBI care.

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