Retrobulbar optic neuritis due to diseases of the posterior sinuses

1927 ◽  
Vol 23 (9) ◽  
pp. 973-973
Author(s):  
N. A. Khristianov

Close anatomical connection between the optic nerve and the posterior nasal appendages and the commonality of their circulatory system explain optic nerve lesions in purulent and catarrhal processes in the posterior sinuses. N.A. Khristianov describes a case of left-sided retrobulbar optic neuritis cured by opening the middle and posterior lattices of the same side, affected by chronic catarrh.

The Lancet ◽  
1986 ◽  
Vol 327 (8496) ◽  
pp. 1490-1491 ◽  
Author(s):  
D.H Miller ◽  
G Johnson ◽  
W.I Mcdonald ◽  
D Macmanus ◽  
E.P.G.H Duboulay ◽  
...  

2010 ◽  
Vol 67 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Ivan Stefanovic ◽  
Milos Jovanovic ◽  
Bojana Dacic-Krnjaja ◽  
Dragan Veselinovic ◽  
Predrag Jovanovic

Background/Aim. Retrobulbar (optic) neuritis is inflammation of the optic nerve that may cause a complete or partial loss of vision. This inflammation can affect a part of the nerve within the eyeball (neuropapillitis) or a part of the nerve behind the eyeball (retrobulbar neuritis). The aim of this study was to establish whether there is a correlation between the diameter of a retrobulbar part of the optic nerve and either visual acuity, prominence of the optic disk (papillitis), or nature of the neuritis (papillitis or retrobulbar). Methods. We tested 23 patients with retrobulbar neuritis and papillitis. In addition to a complete ophthalmologic examination, the diameter of retrobulbar region of the optic nerve was measured by the B-scan method. Following this, the 30-degree test was carried out. Results. We found an increased thickness of the retrobulbar region in 22 patients and different responses to the 30-degree test, as well as a statistically significant negative correlation between the thickness of retrobulbar part of the optic nerve and visual acuity. Conclusion. The retrobulbar part of the optic nerve is thicker in 94% of the patients with retrobulbar neuritis and in all the patients with papillitis. There is a correlation between the reduction of visual acuity and thickening of a retrobulbar part.


2020 ◽  
Vol 46 ◽  
pp. 102558
Author(s):  
Edgar Carnero Contentti ◽  
Guillermo Delgado-García ◽  
Pablo A. López ◽  
Juan Criniti ◽  
Juan Pablo Pettinicchi ◽  
...  

2011 ◽  
Vol 21 (4) ◽  
pp. 513-515 ◽  
Author(s):  
Hyun Kyung Cho ◽  
Shin Hae Park ◽  
Sun Young Shin

1993 ◽  
Vol 35 (2) ◽  
pp. 156-158 ◽  
Author(s):  
D. H. Miller ◽  
D. G. Mac Manus ◽  
P. A. Bartlett ◽  
R. Kapoor ◽  
S. P. Morrissey ◽  
...  

Neurology ◽  
2020 ◽  
Vol 94 (23) ◽  
pp. e2468-e2478 ◽  
Author(s):  
Jean-Baptiste Davion ◽  
Renaud Lopes ◽  
Élodie Drumez ◽  
Julien Labreuche ◽  
Nawal Hadhoum ◽  
...  

ObjectiveTo evaluate the frequency of asymptomatic optic nerve lesions and their role in the asymptomatic retinal neuroaxonal loss observed in multiple sclerosis (MS).MethodsWe included patients with remitting-relapsing MS in the VWIMS study (Analysis of Neurodegenerative Process Within Visual Ways In Multiple Sclerosis) (ClinicalTrials.gov Identifier: 03656055). Included patients underwent optical coherence tomography (OCT), optic nerve and brain MRI, and low-contrast visual acuity measurement. In eyes of patients with MS without optic neuritis (MS-NON), an optic nerve lesion on MRI (3D double inversion recovery [DIR] sequence) was considered as an asymptomatic lesion. We considered the following OCT/MRI measures: peripapillary retinal nerve fiber layer thickness, macular ganglion cell + inner plexiform layer (mGCIPL) volumes, optic nerve lesion length, T2 lesion burden, and fractional anisotropy within optic radiations.ResultsAn optic nerve lesion was detected in half of MS-NON eyes. Compared to optic nerves without any lesion and independently of the optic radiation lesions, the asymptomatic lesions were associated with thinner inner retinal layers (p < 0.0001) and a lower contrast visual acuity (p ≤ 0.003). Within eyes with asymptomatic optic nerve lesions, optic nerve lesion length was the only MRI measure significantly associated with retinal neuroaxonal loss (p < 0.03). Intereye mGCIPL thickness difference (IETD) was lower in patients with bilateral optic nerve DIR hypersignal compared to patients with unilateral hypersignal (p = 0.0317). For the diagnosis of history of optic neuritis, sensitivity of 3D DIR and of mGCIPL IETD were 84.9% and 63.5%, respectively.ConclusionsAsymptomatic optic nerve lesions are an underestimated and preponderant cause of retinal neuroaxonal loss in MS. 3D DIR sequence may be more sensitive than IETD measured by OCT for the detection of optic nerve lesions.


2010 ◽  
Vol 16 (7) ◽  
pp. 786-795 ◽  
Author(s):  
Alexandr Klistorner ◽  
Hemamalini Arvind ◽  
Raymond Garrick ◽  
Con Yiannikas ◽  
Mark Paine ◽  
...  

Optic neuritis provides an in vivo model to study demyelination. The effects of myelin loss and recovery can be measured by the latency of the multifocal visual evoked potentials. We investigated whether the extent of initial inflammatory demyelination in optic neuritis correlates with the remyelinating capacity of the optic nerve. Forty subjects with acute unilateral optic neuritis and good visual recovery underwent multifocal visual evoked potentials testing at 1, 3, 6 and 12 months. Average latency changes were analyzed. Extensive latency delay at baseline significantly improved over time with rate of recovery slowed down after 6 months. Magnitude of latency recovery was independent of initial latency delay. Latency recovery ranged from 7 to 17 ms across the whole patient cohort (average = 11.3 (3.1) ms) despite the fact that in a number of cases the baseline latency delay was more than 35—40 ms. Optic nerve lesions tend to remyelinate at a particular rate irrespective of the size of the initial demyelinated zone with smaller lesions accomplishing recovery more completely. The extent of the initial inflammatory demyelination is probably the single most important factor determining completeness of remyelination. The time period favorable to remyelination is likely to be within the first 6 months after the attack.


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