scholarly journals About the development of bone tissue in goiter

2021 ◽  
Vol 18 (2) ◽  
pp. 45-48
Author(s):  
L. A. Kulesh

In May 1921, a patient with a significant goiter came to the Faculty Surgical Clinic of Kazan University for an outpatient appointment with a request for an operation. The patient was admitted to the clinic, and in view of the rare and extremely interesting features that the goiter presented in her during its objective study, this case was kindly provided to me by the then temporarily in charge of the clinic, prof. VN Larin for research and description.

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
W Kuroczynski ◽  
C Kampmann ◽  
R Huth ◽  
M Hartert ◽  
M Heinemann ◽  
...  
Keyword(s):  

Author(s):  
D. A. Petrochenkov

Fossils of marine reptiles are a new jewelry and ornamental material and collected in the Ulyanovsk region from the Upper Jurassic deposits. They consist of (wt. %): calcite — 52, apatite — 24 and pyrite — 23, and also gypsum presents. The contents of radioactive and carcinogenic elements are close to background. The original bone structure of reptiles is preserved. Apatite replaces the bone tissue of marine reptiles, forming a cellular framework. According to the chemical composition, apatite refers to fluorohydroxyapatite with an increased Sr content. The size of the crystals is finely-dispersed. Calcite and pyrite fill the central parts of the cells. Calcite crystals of isometric and elongated shape, 0,01—0,05 mm in size, form blocks up to 0,3 mm during intergrowth. Calcite fills thin, discontinuous veins along the contour of cells with a width of up to 0,03 mm. In calcite, among the impurity elements, there are (wt. %, on the average): Mg — 0,30, Mn — 0,39 and Fe — 0,96. Pyrite forms a dispersed impregnation in calcite and apatite, content of impurities is, wt. %: Ni — up to 0,96 and Cu — up to 0,24. On technological and decorative characteristics of fossils of sea reptiles of Ulyanovsk region are qualitative jewelry and ornamental materials of biomineral group, allowing to make a wide assortment of jewelry and souvenir products.


2016 ◽  
Vol 19 (2) ◽  
pp. 93-100
Author(s):  
Lalita El Milla

Scaffolds is three dimensional structure that serves as a framework for bone growth. Natural materials are often used in synthesis of bone tissue engineering scaffolds with respect to compliance with the content of the human body. Among the materials used to make scafffold was hydroxyapatite, alginate and chitosan. Hydroxyapatite powder obtained by mixing phosphoric acid and calcium hydroxide, alginate powders extracted from brown algae and chitosan powder acetylated from crab. The purpose of this study was to examine the functional groups of hydroxyapatite, alginate and chitosan. The method used in this study was laboratory experimental using Fourier Transform Infrared (FTIR) spectroscopy for hydroxyapatite, alginate and chitosan powders. The results indicated the presence of functional groups PO43-, O-H and CO32- in hydroxyapatite. In alginate there were O-H, C=O, COOH and C-O-C functional groups, whereas in chitosan there were O-H, N-H, C=O, C-N, and C-O-C. It was concluded that the third material containing functional groups as found in humans that correspond to the scaffolds material in bone tissue engineering.


2019 ◽  
Vol 608 ◽  
pp. 247-262 ◽  
Author(s):  
MD Ramirez ◽  
JA Miller ◽  
E Parks ◽  
L Avens ◽  
LR Goshe ◽  
...  

2002 ◽  
Vol 8 (5-6) ◽  
pp. 71-76
Author(s):  
N.V. Rodionova ◽  
◽  
V.S. Oganov ◽  
Keyword(s):  

Author(s):  
Mariane Beatriz Sordi ◽  
Ariadne Cristiane Cabral da Cruz ◽  
Águedo Aragones ◽  
Mabel Mariela Rodríguez Cordeiro ◽  
Ricardo de Souza Magini

The aim of this study was to synthesize, characterize, and evaluate degradation and biocompatibility of poly(lactic-co-glycolic acid) + hydroxyapatite / β-tricalcium phosphate (PLGA+HA/βTCP) scaffolds incorporating simvastatin (SIM) to verify if this biomaterial might be promising for bone tissue engineering. Samples were obtained by the solvent evaporation technique. Biphasic ceramic particles (70% HA, 30% βTCP) were added to PLGA in a ratio of 1:1. Samples with SIM received 1% (m:m) of this medication. Scaffolds were synthesized in a cylindric-shape and sterilized by ethylene oxide. For degradation analysis, samples were immersed in PBS at 37 °C under constant stirring for 7, 14, 21, and 28 days. Non-degraded samples were taken as reference. Mass variation, scanning electron microscopy, porosity analysis, Fourier transform infrared spectroscopy, differential scanning calorimetry, and thermogravimetry were performed to evaluate physico-chemical properties. Wettability and cytotoxicity tests were conducted to evaluate the biocompatibility. Microscopic images revealed the presence of macro, meso, and micropores in the polymer structure with HA/βTCP particles homogeneously dispersed. Chemical and thermal analyses presented very similar results for both PLGA+HA/βTCP and PLGA+HA/βTCP+SIM. The incorporation of simvastatin improved the hydrophilicity of scaffolds. Additionally, PLGA+HA/βTCP and PLGA+HA/βTCP+SIM scaffolds were biocompatible for osteoblasts and mesenchymal stem cells. In summary, PLGA+HA/βTCP scaffolds incorporating simvastatin presented adequate structural, chemical, thermal, and biological properties for bone tissue engineering.


2014 ◽  
Vol 0 (3) ◽  
pp. 24 ◽  
Author(s):  
Volodymyr Filipenko ◽  
Inna Batura ◽  
Anatoliy Andreyev ◽  
Оleksey Marushchak

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