scholarly journals Morphology of cerebral cortex vessels in experimental epilepsy

1997 ◽  
Vol 78 (1) ◽  
pp. 45-49
Author(s):  
F. A. Yakhin ◽  
E. N. Popova ◽  
F. F. Yakhina

The reversible changes of cerebral cortex vessels prevail in cerebrovascular ischemia caused by unilateral ligation of the common carotid artery in rats. In bilateral ligation of the common carotid arteries, vertebral arteries, stenosis of ascending aorta the dystrophic vascular changes are manifested significantly. In postepileptic period in the presence of cerebrovascular disorders the dystrophic changes of cerebral cortex vessels prevail. In audiogenic epilepsies in the presence of renal hypertension and alimentary atherosclerosis the dystrophic changes of the vessels increase.

2020 ◽  
Vol 50 (6) ◽  
pp. 804-809
Author(s):  
D. B. Avdeev ◽  
S. S. Stepanov ◽  
A. V. Gorbunova ◽  
V. A. Akulinin ◽  
A. Yu. Shoronova

1962 ◽  
Vol 202 (5) ◽  
pp. 1024-1028 ◽  
Author(s):  
Frederick F. Kao ◽  
Remedios G. Suntay ◽  
William K. Li

The effect of CO2 on ventilation was studied in cross-circulated dogs. In these experiments the recipient dog's head was perfused exclusively by arterial blood from the donor dog through anastomoses of the common carotid arteries of the donor to the vertebral arteries of the recipient. The carotid arteries of the recipient dog, as well as its muscles in the neck, were tied. The injection of lipiodol and latex did not reveal leakage from the recipient's head to its body or vice versa. Ventilation and arterial Pco2 of both dogs were determined before, during, and after the inhalation of carbon dioxide of 3, 5, and 7% with 20% oxygen and balance nitrogen by the donor for 20 min or more. The sensitivity of the respiratory centers of both dogs to Pco2 was similar, as indicated by the regression lines relating ventilation in both dogs as a function of arterial Pco2 of the donor dog only. The blood of the recipient's body was hypocapnic when its head was receiving hypercapnic blood. The sensitivity coefficient in both dogs was similar to that of decerebrate dogs during CO2 inhalation. It is inferred that the central CO2 chemoreceptors can account for all the ventilatory response to CO2 inhalation.


2011 ◽  
Vol 68 (9) ◽  
pp. 733-738 ◽  
Author(s):  
Olivera Jovanikic ◽  
Toplica Lepic ◽  
Ranko Raicevic ◽  
Dragana Veljancic ◽  
Andjelka Ristic ◽  
...  

Bacground/Aim. An integral part of Doppler ultrasound examination of cervical blood vessels is determination of intimomedial thicknes (IMT) of the common carotid. The aim of the study was to estimate the relations between IMT of the common carotid and vertebral arteries in order to determine if the value of IMT obtained on the vertebral artery could be applied in clinical practice. Methods. We measured IMT in a randomized, prospective and crosssectional study, performed on 50 persons both sexes (29 men and 21 women), at the age from 18 to 79 years (mean age 52.4 ? 17.63 years). All the persons were healthy, what was confirmed with clinical examination and laboratory analyses. Measurements were perfomed from January 2006 until September 2008. Intimomedial thickness was recorded by twodimensional ultrasonography in B-mode on both common carotid arteries: one value was obtained as average of three successeful measurements (measurements were perform on different places). We measured IMT on the first segment of both vertebral arteries, 1.5 cm proximal from the connection of the first and second segments (we got results of the measurement of IMT on the vertebral arteries in the same way: mean value from the three records). Results. (IMT = 0.782 ? 0.248 mm), obtained from 50 healthy persons, was higher than that measured on the vertabral artery on the first segment (IMT = 0.585 ? 0.134 mm). The values of IMT after measurement on two different places were statistically highly different (t = 7.03, SD = 0.028, p < 0.01). Coefficient of variability of IMT values in carotid circulation (CV = 34.4%) was higher than that in vertebral circulation (22.9%). Values of IMT on vertebral arteries were in statistically significant correlation with those in carotid circulation (r = 0.24 and t- = 2.48; p < 0.02). There were no statistically significant difference between IMT measurement on the right and the left side so they were analysed as the same set Conclusion. Values of IMT on the vertebral arteries are one more undependent parameter of doplersonographic examination of cervical vessels, which significantly correlates with IMT values on common carotid artery. Variability of this parameter is lower, and absolute values lower than the same in the common carotid artery. Therefore, this parameter is probably not so sensitive. On the other hand, lower variability of IMT values on the vertebral artery might be of higher specificity for prediction of atherosclerotic progress by the increased values of this parameter than based on IMT values obtained on the common carotid arteries.


Cureus ◽  
2018 ◽  
Author(s):  
Lexian J McBain ◽  
Joe Iwanaga ◽  
Rod J Oskouian ◽  
Marios Loukas ◽  
R. Shane Tubbs

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Steven C Masley ◽  
Richard Roetzheim ◽  
Timothy P McNamara ◽  
Lucas V Masley ◽  
Douglas D Schocken

Introduction: Cardiovascular disease (CVD) remains the number one cause of mortality in the western world. Carotid intimal media thickness (carotid IMT) is a safe and reliable predictor of future CVD risk. Hypothesis: The study aims to assess the hypothesis that lifestyle factors impact carotid IMT, and determine which nutrition and fitness risk factors best predict mean carotid IMT scores. Methods: A prospective cross-sectional analysis of 592 men and women undergoing health and cardiovascular risk screening. This study reflects the first visit of these subjects, age 23 to 65 (mean = 48.2), who are followed longitudinally and who were participants at a “wellness” oriented program for patients who are generally well-educated and mostly in good health. Measurements were made of fitness using VO2max stress testing and push-up and sit-up scores following the American College of Sports Medicine testing protocols, diet intake using a 3-day dietary intake survey and computerized analyses. Mean carotid IMT scores were obtained using high resolution B-mode ultrasonography of the common carotid arteries. Each subject had ≥10 images collected from the far wall of the right and left distal 1 cm of the common carotid arteries at end diastole. The carotid intimal thickness was measured as a continuous variable, using both multivariate linear and bivariate linear regression. Multivariate analyses adjusted for potential confounders using multiple linear regression and included measures of body composition, blood pressure, fasting lipid and glucose levels, and statin use. Results: Multivariate analyses show that higher mean carotid IMT values are associated with increasing age (p<0.0001), male gender (p<.0.0001), lower aerobic capacity (p=0.0045), lower intake of fish (p=0.05), and lower intake of zinc (p=0.0002). Bivariate analyses controlling for age and gender, with and without statin use, showed higher mean carotid IMT scores were statistically associated with lower levels of aerobic fitness, (p = 0.0007), lower intake of fiber (p=0.02) and lower intake of magnesium (p=0.019). Intake of protein, carbohydrate, and fat as percent of calories; as well as intake of saturated fat, sodium, calcium, potassium, and vitamin K; measures of strength (assessed with push-up and sit-up testing); and self-reported exercise minutes per week were not associated with mean carotid IMT scores. Conclusions: In this database, aerobic fitness and dietary intake of fiber, fish, magnesium, and zinc are associated with lower carotid IMT scores. Further studies are warranted to explore the impact of emerging lifestyle factors on cardiovascular risk and clinical outcomes.


2017 ◽  
Vol 17 (2) ◽  
pp. 95-101 ◽  
Author(s):  
Mohamed Ibrahim ◽  
Bushra Hussein A. Malik ◽  
Moawia Gameraddin

1992 ◽  
Vol 114 (1) ◽  
pp. 147-149 ◽  
Author(s):  
C. G. Caro ◽  
C. L. Dumoulin ◽  
J. M. R. Graham ◽  
K. H. Parker ◽  
S. P. Souza

The blood flow in arteries affects both the biology of the vessels and the development of atherosclerosis. The flow is three dimensional, unsteady, and difficult to measure or to model computationally. We have used phase-shift-based magnetic resonance angiography to image and measure the flow in the common carotid arteries of a healthy human subject. There was curvature of the vessels and thin-slice dynamic flow imaging showed evidence of the presence of secondary motions. Flexing the cervical spine straightened the vessels and reduced the asymmetry of the flow.


2015 ◽  
Vol 120 (10) ◽  
pp. 982-988
Author(s):  
Abolhassan Shakeri ◽  
Mojtaba Varshochi ◽  
Naser Atapour ◽  
Masoud Nemati ◽  
Manoochehr Khoshbaten ◽  
...  

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